I can extract side effects

Department of Urology, Kunming First People's Hospital.

"What? You Sanqing made an artificial bladder again?"

"The clinical trial has been approved? This, this, is really great."

"Don't worry, I'll find you a few patients for clinical trials right away."

Director Wu put down the phone and walked up and down the office excitedly, unable to calm down for a long time.

As the director of the urology department, he has seen too many patients with urine bags hanging on them every day, and their lives are worse than death.

Many of these patients are still very young, and they had a good time, but because of the disease, their entire lives were completely destroyed.

It's embarrassing!

They must be notified as soon as possible, come over to modify the bladder, and remove the urine bag.

Thinking of this, he immediately went back to his desk and flipped through the case records in the computer.

"Female, 16 years old, her bladder ruptured due to a car accident, her intestines were in poor condition, she couldn't retrieve her intestines to rebuild her bladder, and she underwent cystostomy. It's too pitiful. I did this operation myself."

Director Wu recalled that lovely and pitiful young girl with a urine bag hanging on her face, and couldn't help but feel a sore nose: "That's her."

"And this, a 10-year-old boy, suffers from severe congenital urinary incontinence, and his bladder is only one-fifth of the size of a normal person. This situation is not easy to undergo surgery, and can only be treated conservatively. According to the family members, the patient has already developed autistic symptoms. If an artificial bladder can be implanted in him, it will certainly greatly improve the quality of life."

"Male, 50 years old, has suffered from uremia for 30 years. His left kidney and bladder have been removed. For the past 30 years, he has to come to the hospital for dialysis every week, and the urinary catheter needs to be changed once a month. The burden on the family is heavy. If you can change him An artificial bladder would definitely improve."

"..."

In just ten minutes, Director Wu picked out five impressive patients. They were either seriously ill, young, or had heavy family burdens. After artificial bladder transplantation, all of them could greatly improve their own conditions and save five suffering patients. Desperate families sinking in the middle of nowhere.

Afterwards, he called the patients and their families one by one to inform them of the good news in person.

As a doctor, he likes to hear the voice of joy from the heart of his patients, and he feels extremely satisfied every time.

*****

50-year-old Lao Li is a person that even doctors find incredible. He undergoes hemodialysis three times a week. He has a loud voice and quick movements. He likes to ride a bicycle when he has nothing to do.

As a kidney fighter, he has struggled with uremia for 30 years and lost a left kidney and a bladder.

He is not like ordinary uremia patients who are dying every day, weak like a candle in the wind, but has a strong vitality.

Except for a yellow urinal bag hanging around his waist, he looks like an ordinary person.

The root cause of Lao Li's illness was an accident when he was 8 years old. He climbed up a tree because of naughtiness, and slipped down suddenly without thinking about being frightened.

At that time, the medical conditions were not good. Lao Li just took some traditional Chinese medicine casually and took it to heart, but he did not expect that the damage to the urethra would cause the bladder and kidneys to be infected.

Since he was 12 years old, he couldn't control his urination. In class, he repeatedly raised his hand to ask for leave to go to the toilet. The teacher only thought he was naughty and often refused to allow him, but he didn't know that the child was so full of suffocation that he was about to cry.

In desperation, Lao Li had no choice but to drop out of school. At that time, he only felt relieved, and never thought that frequent urination was due to his bladder shrinking.

Later, the frequency of urination became more and more serious, and the family went to the local hospital to see a doctor, but they couldn't see why.

When he was 20 years old, Lao Li suddenly bled heavily when he urinated, and he collapsed.

The local doctors were helpless and sent him to a higher-level hospital. The doctor said that his left kidney and bladder had been necrotic.

In order to save his life, he lost two of the most important urinary organs, and he had an extra stoma and a urine bag on his right waist for urinating.

Later, he got uremia again and needed hemodialysis three times a week.

At the age of 40, uremia caused heart failure, which is the most dangerous complication. Lao Li felt that he had only one breath left, but was miraculously rescued by the doctor again.

Passing by the ghost gate many times, but Lao Li still lives well, optimistic and happy.

For 30 years, he has been living with a urine bag. Although he is just an ordinary security guard, he has lived a cautious life, but he has never given up on life.

In his spare time, he bought books from bookstores and taught himself the erhu and pipa. His good piano skills made him a celebrity in the community, and he even had a female fan, forming a harmonious family.

Being able to have such a state stems from his free and easy mentality of treating himself as a normal person.

Regardless of work and life, he demands himself by the standards of normal people. Even in the summer before, he took a urine bag to go swimming in public places, and he didn't feel anything unusual.

He didn't care about those strange eyes, so he just didn't see them.

Over time, this has also won him the respect of many people.

Due to his illness for many years, he also met many doctors in the department of urology and nephrology, and he was an old acquaintance with Director Wu.

On this day, as usual, he played the erhu in the community and communicated with a group of piano friends.

Suddenly, the phone rang.

Lao Li picked up the phone: "Hey, Director Wu, what's the matter?"

With a thud, the phone slipped from the hand of the head and fell straight to the ground.

But Lao Li didn't realize it, and he froze on the spot.

It wasn't until his wife pushed him aside that he exclaimed as if he had just woken up from a dream.

"I, am I going to have a new bladder?"

He glanced at his feet and quickly picked up the phone. Fortunately, the thick phone case saved the screen from breaking.

When the wife heard this, she was also taken aback: "New onlooker? What do you mean?"

Lao Li hugged his wife and refused to let go for a long time. He murmured in a low voice, "Director Wu said he would give me a brand new bladder."

Before he knew it, tears of joy filled his face.

The wife was stunned for a moment: "Didn't your bladder be cut early? Can it grow back?"

The Qin friends next to each other also opened their eyes wide, as if they heard something from the Arabian Nights.

Lao Li wiped away the tears on his face like wiping sweat, and explained to everyone.

"It's not a regrowth, it's a transplant of an artificial bladder. Oh, I can't explain how complicated it is, but this is a new research and development achievement of the Sanqing Group, so it shouldn't be fake."

"Oh, Sanqing's new achievements, it should be true."

Everyone suddenly realized, believed him immediately, and congratulated him one by one.

"Old Li, it's time for you to catch up with the good time. It's really lucky to have a new one transplanted after the bladder is gone."

"Do you want to conduct some kind of clinical trial? It's very popular now. Last time, my old man also got some kind of disease. He also participated in a clinical trial in his seventies and eighties, which is very foreign."

"After 30 years, Lao Li's bladder has finally returned, which is really gratifying."

"After the surgery, we will set up a table for you to celebrate."

The wife is also very happy. She doesn't understand how this is done. It can only be attributed to the power of technology.

"Then you have a new bladder, so you don't need to hang a urine bag in the future?"

Lao Li patted the urine bag under his coat. It was bulging inside, and he felt mixed feelings. Thinking about how this urine bag had been with him for 30 years, he might not be used to it if it disappeared in the future.

But he didn't miss it, but felt a burst of joy in his chest, nodded and said: "That's right, this thing will never be needed again in the future."

The next day, Lao Li came to Kunming People's Hospital as scheduled and met Director Wu.

After greeting with a big smile, he saw the other four patients in the office.

In addition to the two middle-aged people, there were also two young patients, so he couldn't help but look at them a few more times.

A girl in school uniform was carrying a shoulder bag with an unsealed zipper, and a yellow urine bag was just placed inside.

Her eyes are calm, she will smile at everyone, she is as calm as an ordinary middle school student passing by on the street.

The two looked at each other and nodded to each other.

Lao Li praised secretly in his heart, he saw his own shadow in this girl, that kind of carefree attitude, so familiar.

It can be predicted that no serious illness can knock her down, and she is destined to grow up happily.

He turned his gaze to the corner.

There stood a silent little boy with his head down, hiding behind his parents and hiding in the shadows, as if this would keep all the unhappiness out and not affect his own small world.

Lao Li glanced up and down, and soon saw the yellow urine bag on the little boy's body. His heart sank and he looked away, not daring to look again.

How old is this child? He should have been innocent, carefree, and growing up healthily, but he was burdened with unbearable pain and an unforeseeable future.

He lamented in his heart, the joy on his face disappeared in an instant, and he couldn't smile anymore.

At this time, Director Wu coughed lightly and began to distribute the documents in his hand.

"This is a consent form for a clinical trial. Take a look. If you have no objections, please sign it. For minors, their family members will sign it."

After everyone signed, five thin documents were stacked neatly on the desk.

Then, five people, with five urine bags hanging, all looked at Director Wu with anticipation in their eyes.

Director Wu chuckled and said, "The clinical trial of the artificial bladder is different from the clinical trial of ordinary drugs. After a while, the five of you will go to the physical examination first, and then get ready for the bladder puncture to collect cells."

"After I get the cells, I will send them to Sanqing's stem cell laboratory, where researchers will cultivate bladder cells based on your detailed body data to create an artificial bladder."

"The whole process will take about one to two months depending on each person's situation. When the bladder is cultured, I will notify you and come over for the transplant."

"Okay, if you have any questions, you can ask them clearly."

The two middle-aged men shook their heads blankly. They were dark-skinned and plainly dressed. They looked like farmers or workers. They didn't even understand Director Wu's words, let alone ask any questions.

The little boy's family members had a lot of questions. They asked a lot, mainly about the precautions before and after the operation.

Director Wu explained patiently: "Your child's bladder is relatively small, the damage is not serious, and the urethra is relatively healthy, so only a part of it needs to be transplanted."

"Researchers will grow a bladder that is about the size of a normal person, and then sew it together with the original bladder, so that the new bladder will continue to grow, reorganize with the old bladder, and replace the non-functional part of the old bladder."

"One month after the operation, the artificial bladder can work like a normal bladder. After three months, the blood vessels around the artificial bladder can grow rapidly, and the nerves will also be connected. The elasticity of the artificial bladder is 3-4 times higher. There is better control over urination and the bag can then be removed."

Hearing this sentence, the little boy suddenly raised his head, his eyes sparkled, and asked the first sentence since he came in.

"Uncle, really?"

Director Wu patted his head lovingly, took out a toffee from his pocket and handed it over, and said with a smile: "Of course it's true, you will be a normal person from now on."

A smile bloomed on the little boy's face, and he laughed happily: "Great, my classmates will never laugh at me again."

He shook his mother's arm, the haze in his eyes was swept away, and he shouted happily: "Dad, Mom, after the operation, I will go to school. I really want to go to school."

The smile on the parent's face was bright, but his voice was trembling. The two bowed to Director Wu, bending their waists deeply.

"Director Wu, thank you."

Director Wu hurriedly helped the two of them up, and said repeatedly: "It should be, it should be."

"Actually, if you want to thank Sanqing, you have to thank Sanqing. It's all the technology they developed. I'm just an operator, hahaha."

"Director Wu, you are being polite. We will send pennants to both sides later on."

Looking at the scene in front of him, Lao Li felt as if something surged up from his chest, and his eyes instantly became moist.

At this moment, Director Wu looked over at him and his face became serious.

"Old Li, your situation is a bit special. It is different from them. Their bladders are partially removed, but yours is completely removed. We are not sure how much tissue is left, whether it has shrunk, and whether it can grow in the bladder. Together."

"And you have a full bladder transplant, and everyone else only needs to transplant a part, so your artificial bladder culture will be a lot of trouble."

"After all, this operation is the first case in China. We cannot guarantee the prognosis of the operation and whether it can achieve the ideal state."

"This point, as a doctor, I have to tell you clearly in advance."

Lao Li grinned: "Director Wu, I haven't had a bladder for 30 years, and I've accepted the reality a long time ago. You see, I'm living a good life with a urine bag on every day."

Director Wu nodded approvingly: "I admire your mentality, you are very optimistic. I am mainly afraid that if you have hope now, the situation will not be ideal and your mentality will not be good."

Lao Li waved his hand, with a look of indifference: "Director Wu, others don't know me, don't you know? I can go swimming with a urine bag in summer, so I'll ask you, this positive attitude, Who can compare."

Director Wu smiled: "Yes."

He didn't say any more, and turned to look at the girl in school uniform: "What about you, you and your mother understand it, right?"

The girl responded crisply: "Understood. But I have a question."

"what is the problem?"

"I just want to ask, will this operation delay my college entrance examination this year?" the girl asked calmly.

"Hiss~" Director Wu gasped, looked the girl up and down, and couldn't believe it: "What? Aren't you only 16 years old? You're not a freshman in high school?"

"I skipped two levels, and it happened to be the college entrance examination this year." The girl said calmly, "But I understand that transplant surgery is a major surgery, and it will indeed have a certain impact on the body. If I don't perform well, I can repeat it next year. It's fine. I’ll just figure it out, so I’ll be mentally prepared.”

Director Wu plucked at the stubble on his chin, and suddenly felt a faint pain in the balls.

It never occurred to him that this child could skip a grade and study while enduring the unbearable pain of ordinary people.

This is a top student, so he can't delay his future.

In case he didn't do a good job in the operation, which affects the child's performance, from 985 to a junior college, or even failed to enter the university.

This... I will definitely feel sorry for myself.

Director Wu was thinking silently, his shoulders were heavy, and he felt a great pressure.