The Godfather of Surgery

Yang Ping sent his wife to the gate of Sanbo Hospital, and then drove to Fuyi District of Nandu.

He was already familiar with Fuyi, so he parked his car in Fuyi and called Professor Yao, who immediately went downstairs to greet Yang Ping.

The Organ Transplantation Center of the First Affiliated to Southern Metropolis, enjoys a high reputation in China because of Professor Yao's ischemia-free transplantation technology.

Professor Yao brought Yang Ping to the doctor's office. The doctors here are not very familiar with Yang Ping. Unlike orthopedics, almost everyone knows this Professor Yang.

This is Professor Yang from Sanbo Hospital! Professor Yao introduced Yang Ping to several chief physicians in the department.

Several chief physicians just nodded symbolically. I have never seen such a young professor before, and he must not be a character.

Professor Yao asked the doctor in charge of the bed to bring the medical records, and Yang Ping read the medical records in detail, not missing a word.

Xu Jiujiang, male, 45 years old, diagnosed with dilated cardiomyopathy.

Since 3 years ago, Mr. Xu would feel palpitations, shortness of breath, and hypoxia as long as he did a little activity. He was diagnosed with dilated cardiomyopathy by a local university hospital. After 3 years of treatment, his condition has not improved. 4 months ago, Mr. Xu's condition began to deteriorate, with frequent episodes of chest tightness, palpitations, shortness of breath, and dizziness, unable to lie down or eat.

This made Mr. Xu deeply despair, knowing that his time was short, but the child was still in high school, and Mr. Xu was not reconciled.

In order to seek a chance of life, Mr. Xu went to Nandu No. 1 to find Professor Yao after inquiring from various sources. Professor Yao conducted a series of inspections on him.

Among them, echocardiography showed that the diameter of the left ventricle has expanded to 76 mm, while the left ventricle of a normal person is about 45 mm, and the volume of the heart is more than 2 times larger than that of a normal person, the cardiac function is very poor, and the left ventricular ejection fraction has dropped to 28. %, and at least 50% of normal people, this kind of heart is already in jeopardy.

After being hospitalized in Nandu No. 1, Professor Yao actively treated him with anti-heart failure treatment. However, due to fluctuations in the systemic circulation and disturbances in the internal environment, Mr. Xu needs to use dopamine and norepinephrine to maintain blood pressure.

In order to relieve the condition and get a chance to wait for the heart, Professor Yao installed an intra-aortic balloon counterpulsation device for Mr. Xu to assist the left ventricle.

Yang Ping already knew about Mr. Xu's basic condition, and now he revisited it and became more familiar with it.

There is only one chance for a heart transplant, so please come over and discuss it together. I once performed a heart transplant of a different blood type, which was a transplant from a donor with type O blood to a patient with type A blood, because type O blood can be compatible with type A. Blood, plus the use of new drugs, the risk of rejection is relatively controllable, so we dared to try it at that time, now this patient has blood type B, and the possible donor is blood type A, a completely incompatible blood type, in a heart transplant Come on, we dare not try.

If it is a young child, the immune mechanism in the body is not yet complete, and you can try a cross-blood type transplant, which may deceive the immune system, but an adult, with a complete immune system, can't try it.

Professor Yao was very polite and shared his difficulties and worries.

At present, if the cross-blood transplantation of kidney transplantation is applied to heart transplantation, it is still a bit rough and inappropriate.

Yang Ping admires Professor Yao quite a lot. His ischemia-free transplantation technology is world-class, but it will take some time to perfect it. Put yourself in a learning position.

Professor Yao really has the demeanor of everyone, and Yang Ping decided to transfer some of his experience to Professor Yao without reservation.

ABO blood type is the basic principle of organ transplant matching. If the blood type is incompatible, the transplant recipient will have a strong immune rejection after surgery.

If a cross-blood type transplant is to be carried out, either the antibodies should be washed thoroughly, or the immune system should be strongly suppressed, so as to ensure that no strong immune rejection occurs, and the transplanted organ can be in harmony with the human body and integrate into the human family.

Several chief physicians around did not understand why Professor Yao respected this young man so much.

Yang Ping thought for a moment and said:

Professor Yao, in fact, this case still needs to use the method of blood washing, but a more advanced method of washing blood is needed. Currently, there is a new method. The research team from the University of Toronto, Canada, uses two enzymes, FpGalNAcdeacetylase and FpGalactosaminidase, and supporting technologies to wash blood types. Antibodies, which can thoroughly wash AB blood group antibodies, turning the organ into a universal donor, are recommended for this technique.

Ordinary blood washing technology has been unable to complete such a difficult blood washing, and can only use new technology.

I have also read this paper, but it is still an experimental technology. I don't know whether the technology is mature, and it is impossible to obtain this set of enzymes and related technologies. Professor Yao is quite embarrassed.

It is not realistic to use this cutting-edge technology. If nothing else, getting this set of enzymes is a problem.

There are only two ways for this patient to be rescued. One way is to obtain a blood type-matched heart donor, and the other way is to obtain the method of the University of Toronto. Which one do you think is more likely? The former depends entirely on luck. The luck of winning the 5 million lottery, and the latter can be achieved. If Professor Yao is willing to give it a try, I can help contact the University of Toronto team and invite you to Professor Li Zehui from the Cleveland Medical Center and his senior brother Dodge, who are all North American hearts. A giant in surgery can help contact the University of Toronto. Yang Ping suggested that Professor Yao give it a go.

Yang Ping has calculated that if this patient does not undergo a heart transplant, there is no chance.

Of course, there is another way to do an artificial heart transplant, get a buffer time, and then wait for the heart transplant, but the cost of an artificial heart suitable for this patient is not affordable for ordinary people, and even if you wait, there is still no chance to obtain a heart of the same blood type.

Professor Yao pondered for a moment, and decided to follow Yang Ping's words and give it a shot.

Then I have to trouble Professor Yang again and help me contact the team at the University of Toronto?

Since borrowing a machine to operate on Yang Ping and getting to know Yang Ping, Professor Yao found that he seemed to be leaning against a big tree.

Well, I'll send an email later, and take the time to prepare to fly over and learn their technology. In fact, I'm familiar with their technology, but you need to get their two blood-washing enzymes. If It takes a long time to prepare these kinds of blood washing enzymes.

Yang Ping reassured Professor Yao that he was not recommending new technologies to him based on a paper.

Yang Ping is indeed very familiar with this new technology.

Because in the system space, when Yang Ping reads the paper, whenever he sees interesting new results, he will find a way to do experiments and play in the system laboratory.

The chief physicians who stood by and listened to Yang Ping and Professor Yao discussing their illness were like listening to a book from heaven.

As for the team from the University of Toronto, if they want to contact them, they will contact them. Also, Li Zehui and Dodge in Cleveland seem to be his brothers. It seems that when he sends an email, others will definitely help him.

And when he said that, he seemed very arrogant.

Professor Yao is very excited to learn the recent washing AB antibody technology of the University of Toronto and get two most advanced enzymes.

With this alone, he can take several steps in the field of organ transplantation.