The Godfather of Surgery

Yang Ping was quite worried about little Andrew's surgery.

Although he has drawn detailed surgical drawings, I am afraid that Robert still cannot achieve satisfactory results.

With Robert's rigor as a doctor, he would definitely not rashly perform this operation, either ask Yang Ping to do it, or wait a few years before Robert masters the operation before doing it.

Robert should choose the former because he is a doctor, a brilliant doctor, who thinks from the patient's point of view, not his own interests.

In Yang Ping's current difficult cases, in addition to little Andrew, there is also Boss Cheng's side. There is a patient with brittle knee joints. He has smashed the operation in Yunjian and plans to go to Liquan Hospital for revision.

Wei Danian, who is admitted to the ICU once a year, has not been diagnosed yet. What is the cause of lactic acidosis?

There was no news in the WeChat group specifically to discuss Wei Danian's condition. It seems that Dr. Wen from Nandu Medical University has not yet returned the results of the genetic test.

Yang Ping was the most devoted, and the most difficult thing was Sisi. Sisi's femur has been extended by more than ten centimeters. Once the target value is reached, the two ends will meet, and the next operation will be to rebuild her thigh muscles.

After many excision operations for the primary tumor, not only the entire femur was removed, but also the surrounding muscles were removed. If the muscles were to be reconstructed, the muscle flaps had to be taken from other places for transplantation.

The muscles of the thigh, whether it is the quadriceps femoris or the biceps femoris, are the strongest muscles in the human body, and it is impossible to find a suitable donor site.

This is a thorny problem, but these can be dealt with slowly. In the last review of Sisi, the tumor treated with Haifu Knife did not find any recurrence for the time being.

But recurrence is a matter of time, and it is almost impossible to remove the spread of tumor cells by surgical means alone.

What if it relapses?

Continue to use the Haifu Knife. This fire-fighting operation cannot touch the source of the fire, and can only be exhausted.

However, for osteosarcoma, there is no specific targeted drug in the world. Except for surgery, radiotherapy and chemotherapy, there is no good way. Relatively speaking, the focused ultrasound of Haifudao is already the best way.

For Sisi, Yang Ping had to think a little longer. Subconsciously, he had made up his mind to go all out, no matter what the outcome was, he would not hesitate.

Therefore, a laboratory for system space rewards is imminent for Yang Ping. He needs a laboratory for research, just like massive surgical training. With this laboratory, he can set up research projects and spend infinite time on research. .

Yang Ping looked at the time on his phone, Song Zimo's surgery should have been done, he got up from the bench and went to the operating room to have a look.

For the first operation, there was no pressure on Song Zimo, and the operation was performed strictly according to the standard procedure.

The steps of the standard process actually correspond to each scoring point, and the two are not contradictory.

Immediately afterwards, Director Han and Professor Zhang also came in, and the two of them were discussing something.

Song Zimo's surgery was impeccable, every step was not redundant or omitted, meticulous but not rigid, and there was no trace of deliberate regulation for the competition.

The judges who watched the live broadcast and scored the scores step by step, full marks, full marks, full marks————

Director Han and Professor Zhang looked very relaxed. Seeing Yang Ping, Director Han waved: Xiao Yang, the stem cell research license of the Institute of Orthopedics has come down. You can see what scientific research projects are there. You can set up a project.

Yang Ping really wants to set up a project for scientific research. For the time being, he wants to focus on the repair of defective tissue, such as the repair of muscle tissue defects. This is the next problem to be solved by Sisi.

Too big a topic, we will talk about it later when we get the System Space Lab.

I want to set up a topic in tissue engineering, which requires stem cells and 3D printing. Yang Ping expressed his thoughts.

The orthopaedic laboratory is for you, and all the equipment can be used casually. Director Han's purpose of building this platform is for young people.

Yang Ping is already familiar with the equipment inside. The 3D printer can print at the macrovision level, but not at the microvision level, and even worse at the nano-level.

This device originally had nano-level micro-vision printing, but when it was introduced, it was a restricted technology, and people were unwilling to sell it, so the corresponding hardware and software modules were castrated.

It is not surprising that once these cutting-edge devices are introduced to China, these foreigners will castrate their functions, intentionally reduce hardware and software modules, and discount their functions, which is called technical limitations.

After Song Zimo's surgery was completed, the video was closed, and the scores already scored were full marks.

This kind of operation is not difficult for any orthopedic surgeon to complete the operation, but it is very difficult to achieve full marks.

Mr. Guo, from the Department of Traumatology, went to the operating room one by one to inform him to invite guests to dinner in the evening, unknowingly thinking that Mr. Guo was married or that the child was full moon.

Mr. Guo is single and has not been promoted recently. What makes him so happy, broadcasts everywhere to invite people to dinner.

It turned out that Mr. Guo ended his one-year hospital life and ended his life of being on call 24 hours a day for 365 days. Of course, it is worth celebrating.

He is going to set up a few tables near the hospital to celebrate, and at the same time, he may wish to inform everyone: those who have sisters, cousins, cousins, and other unmarried female relatives and friends can now officially introduce them to him.

This meal is not eaten for nothing. Anyone who hears the news from the orthopedics department shouts to get together at night.

Seeing that Song Zimo completed the first operation of the Golden Knife Award, Director Han and Professor Zhang had nothing to do and planned to leave. Director Han instructed Yang Ping to take out the project as soon as possible, and he helped apply for funds.

Taking advantage of Yang Ping's free time, Takahashi came over and said, Can we play tennis together after get off work in the afternoon?

Yang Ping finds it strange that he plays tennis, and baking soda, and the mandarin duck ball, what are you involved in?

Takahashi smiled and said, That's not what I meant—

Then he pointed to Fujiwara Miyuki who was chatting with Xiao Su and asking about equipment.

It's her, Dr. Fujiwara, in the hospital gym. She saw you and Nurse Su playing ball several times. She asked me to tell you and play tennis together. in spite of.

She's a great tennis player! Takahashi added.

Yang Ping saw that they were so interested, so it was okay to play ball together: Okay, Mr. Guo of the Trauma Orthopedics Department treats guests in the afternoon. Let's have dinner together, and then go to play ball after dinner.

After the operation for the Golden Knife Award, there are still a few more operations, all of which are performed by Song Zimo and Xu Zhiliang, and Yang Ping is also very free in the operating room.

He just wanted to communicate with Takahashi about tissue engineering, what new research trends are there at the University of Tokyo.

After chatting for so long, Gao Qiao was still standing, Yang Ping asked him to move a stool and sit down, and he moved a round stool to sit beside Yang Ping.

In terms of tissue engineering, especially the application of stem cells in tissue engineering, what progress have you made? Yang Ping asked Gaoqiao.

Takahashi is very familiar with these, and he speaks endlessly: Duke University in the United States successfully used stem cells to grow muscles for the first time, and the stem cell laboratory at the University of Tokyo followed, and soon after, muscles were also grown, and these muscles had normal muscles. function, can receive stimulation and contract.

They used pluripotent stem cells, injected a large amount of Pax7 protein into them, used these proteins to signal the stem cells, and then directed the stem cells to differentiate into muscle cells. Once differentiation was complete, they stopped the injection of Pax7 protein and instead provided the muscle cell development. These muscle cells can maintain stable division and development under the nutrient supply. On the prefabricated nano-3D template, after three to four weeks of culture, muscle cells will aggregate to form muscle fibers, which are similar to normal human muscle fibers. When stimulated, they can contract, but the strength and strength are not as good as natural muscles. They transplanted the cultivated muscles into mice and obtained three weeks of survival time. During the survival period, they had normal muscle function.

The Stem Cell Laboratory of the University of Tokyo. I am one of the main leaders of this project. The key to the technology lies in the differentiation and guidance of stem cells and the printing of nano-scale 3D scaffolds. At present, our common obstacle is that the survival time of cultured muscle cells in experimental animals is longer than that of experimental animals. Short, our time can be extended to six weeks, twice that of the United States, but in the end, muscle cells still disintegrate. If the mystery of disintegration can be solved, infinite muscles can be cultivated in the laboratory in the future. Looking for the differentiation-inducing substances of various tissues, so that the differentiation of any tissue is not a problem, but unfortunately, at present, whether it is the United States or us, only one differentiation substance-Pax7 protein has been mastered.

Takahashi has no doubts about Yang Ping's ability, and he is very eager to establish cooperation with Yang Ping to carry out this project together, because he encountered resistance in this project and could no longer continue to break through.

I just learned from Director Han about the equipment of the orthopaedic laboratory. The 3D printer does not have the capability of micro-vision printing. This function has been castrated by German manufacturers.

Because of these cutting-edge technologies, they need to be kept secret. At present, only the macro-vision printing function is open. As for micro-vision printing, no matter how much money is paid, no one will sell it. Therefore, this machine cannot perform nano-level micro-vision printing. It lacks physical and software module.

To carry out this experiment, the 3D modular scaffold for growing muscles is indispensable to guide the arrangement of muscle cells.

I want to set up this topic at the Institute of Orthopedics, which is also to use stem cells to cultivate muscle tissue. Regarding the problem of disintegration, the problem lies in mitochondria, which is equivalent to the mechanism of cell aging and death, but it is an accelerated version of this mechanism. I set up this topic , is to fix this, you and the Americans are stuck in a dead end—

In the system space, the knowledge gained by Yang Ping using massive data is not comparable to Takahashi in terms of breadth and depth.

It's just that Yang Ping has not conducted such experiments so far. If he can cooperate with Takahashi, he can use chickens to lay eggs, which will save a lot of time than starting from scratch.

Yang Ping pointed out the method of breaking the subject in one sentence, but he stopped talking halfway through.

It is equivalent to patting the pocket, there is the sound of the key inside, but just don't take out the key: The key is here!

Takahashi has a deep understanding of Yang Ping's high IQ, and he is convinced that working with Yang Ping can find a way to break through.

But Yang Ping did not propose cooperation, but simply stated that Takahashi and the Americans had strayed into the puzzle.

Dr. Yang, if you are interested, can we work together? Takahashi probed.

Yang Ping doesn't seem to be interested: My starting point is relatively high. If I cooperate, I don't want to do those basic things. I'm only responsible for prolonging the lifespan of the cultured muscle cells.

Yes! Takahashi is very happy, this is what they want, and they can't break through.