Rebirth of the God-level Xueba

"Professor Yu, can the University of Science and Technology of China not use solanesol to chemically synthesize coenzyme Q10?" Director Hai was sweating while holding the phone.

The voice of the phone is a bit distorted, but it clearly said: "Our institute has no special research in this area, but as far as I know, there is no precedent for this technology in China. The Beijing Institute of Biological Products seems to have done similar projects. , You can inquire about it."

"I've called, and they have abandoned the project." Director Hai squeezed the phone, feeling strange.

Even the project that the Beijing Institute of Biological Products did not make was made by Yang Rui. Had it not been for the precedent of the WestJet factory, he would have encountered a liar.

But if it’s not a liar, this technology is too powerful, no wonder that Zelecom easily agreed to downgrade shares, and it’s not like the last time it required technology transfer.

It seems that they knew that the value of technology was too high, so they simply did not discuss the issue of technology transfer.

Perhaps, I hope that after the factory is put into production, it will steal lessons from it.

Chief Hai was amused by his own thoughts, and when he changed his mind, he felt proud that foreigners stole a teacher from China. Domestic magazines and newspapers like to write such stories, but only those in the professional field know that now China and Foreign countries, how big is the gap

A full 10 years of wastefulness has brought about more than 10 years of backwardness. It should be 20 or 30 years. It is also in the field of biotechnology. China’s technology is still stuck, or the highest peak of Chinese technology is staying. Synthetic insulin is one item

However, synthetic insulin in the 1960s was not a rare thing in the 1980s. However, there are not many people who can replicate this experiment in China.

Professor Yu gave a natural "Oh" on the other side of the phone, and laughed: "It's a pity to give up, and it's not surprising. In the past two years, too many items have been cut down. Coenzyme Q10 is not an important drug related to the national economy and the people's livelihood.

"Then you said, if the University of Science and Technology of China or the Beijing Institute of Biological Products restarts the project, how long will it take to see the results?

"Our school will not do this project." Professor Yu came in a hearty voice and said with a smile: "Our school's current goal is to track the latest international basic research, such as biological macromolecules, stem cells, gene functional groups, etc. Etc., the production of coenzyme Q10 is of an application nature, even if there is national funding, it may not be able to allocate manpower.

"Then the Beijing Institute of Biological Products restarts the project, how long do you think it will be done?"

"This is hard to say."

"Professor Yu, we are so familiar, so you can analyze it, so I know how to make a decision." Director Hai said a little. Although he is in charge of the sales of raw materials and refined chemicals throughout the country, he has Four departments, more than twenty people, none of them can do research. Whenever he encounters such a thing, he always asks a professor who is familiar with it.

Professor Yu is also willing to maintain a mutually beneficial relationship with Director Hai. He pondered for a moment and said: "I can't do analysis for others. I'll just guess. If this technology is restarted, whether the research can produce results is actually a bit of luck.

"How to say?

"Laboratory technology for 20 to 30 years, why can't we do factory conversion? There are many reasons inside. The main point is that the nature of Coenzyme Q10 is relatively special, and its intermediates are not stable enough. Therefore, laboratory technology cannot Directly used in the factory, factory production, is equivalent to a new way to produce substance A through solanesol, and then convert it into substances B, C, D, and finally to coenzyme Q10, all of which must be stable Matter, you say it’s easy or not?" Professor Yu has a tone of teaching students.

Director Hai listened very seriously, and asked, "I don't know much about technology, so I just want to ask, isn't it also true of other factory-based production technologies?

"Not all, some laboratory technology can be used directly in the factory, because the route it takes in the laboratory and the intermediate products it passes through are suitable for the factory. Let me make an analogy. Chemical synthesis is like From one place to another, the intermediate product is the bridge to be passed. There are four intermediate products, that is, there are four bridges. Laboratory technology is like a human walking. Any bridge can be used, pontoon bridges, wooden bridges, and stone bridges. Bridges are also good, and researchers don’t force them. Wooden bridges are used, stone bridges are stone bridges, and pontoon bridges are used. Factory production is like a truck pulling goods, and its conditions are harsh. Well, at least it must be a stone bridge. If the scale of the factory is large, it must be a railway bridge. Do you understand?"

"That is to say, some laboratory technologies happen to be above the stone bridge. Coenzyme Q10 technologies are all wooden bridges and floating bridges?"

"That's what it means, but it's more than that. Think about it. Even if the first three bridges are stone bridges, and the fourth bridge is not a stone bridge, you still can’t pass, you have to go back to the third, or second. The first bridge, and even the first bridge, start again. If you can’t find the way to the whole stone bridge, this synthesis scheme will never be used. The semi-chemical synthesis of coenzyme Q10 has been around for a long time, indicating that many people have explored I’ve passed, but it’s not working now. It means that it’s very difficult. You want to know how long it will take to make it. I don’t think no one dares to make a guarantee."

Director Hai had thoughts in his heart, and at the same time he was amazed at Yang Rui's level again.

He doesn't know much about technology, but he is a man who knows how to do it. If one time technical success is luck, it will be difficult to say that the second time.

However, Director Hai did not see anything after all, so he tentatively asked: "Professor Yu, if I say that a student has developed this technique, what do you think?

"A student did it? Which school?

"I haven't verified it yet." Director Hai lied and said, "You think that a person, a student, has solved this factory chemical synthesis route. Do you think it is possible?

There was a full ten seconds of silence on the other end of the phone before Professor Yu’s voice continued: “If you have the right equipment, equipment, systematic training, knowledge reserves, plus luck, you can do it alone. No. Students are also strong and weak. It’s not that you can’t do it, but it’s not easy... Let me say that if someone can complete this technology independently, whether it’s a student or a farmer, the domestic research institute should be open. The door is arranged.

Director Hai had thoughts and said, "I understand, if the technology is proved to be true, are you interested in taking a look?"

Zeneca reduced its shares from 50% to 45%, not simply reducing it by 5%, but giving up the controlling stake. If Yang Rui and Sinopharm’s foreign trade unite, they can determine the direction of the new joint venture factory.

Director Hai feels that if Yang Rui is pulled into the system and enters a certain research institute, TCM’s control over foreign trade will be greatly enhanced.

This idea was considered as early as in the WestJet factory, but now it has only strengthened this idea.

He felt that with Professor Yu’s help, whether it was from the research institute or Yang Rui, he would speak better.

Professor Yu was also curious about what he said, and said: "You have confirmed the technology. I must take a look. If possible, you can come to the University of Science and Technology of China and show it to our students and teachers. If it is not convenient, I will Take time out.

"We'll show you how to let you run over." Chief Hai laughed and spoke nicely.

Just like Shen Pinghui, the director of the Pingjiang Institute of Biotechnology, when necessary, he will appear in front of provincial leaders as an authority on biology in the province. The University of Science and Technology of China, currently known as China’s number one university, is in contact with political circles in the academic world. He is not behind on the road, and Professor Yu’s reputation in the circle is also quite high.

This kind of big cow-level figure, and ordinary little professor, are of two levels, and Chief Hai has to be careful.

After finishing the phone call with Professor Yu, Director Hai waited for two days with peace of mind, and finally met Trapp, the chief representative of Zelecom, who had flown from the UK.

He brought four of his men this time, as well as more than a dozen instruments that can fit a jeep. Trapp has learned how difficult it is to borrow instruments in China. I don't want to experience it again this time.

Domestic research institutes, in many cases, do not give people direct use of the instrument, but ask you to list the requirements, and then send someone to operate it, for fear that any mistake will damage the instrument.

Trapp is not accustomed to this approach. When he came this time, he simply installed a car of instruments from Hong Kong, and prepared to donate to several universities in China when it was used up. This is also one of the various agreements that Zelecom has invested in China. .

Trapp sent the instrument to Xibao Middle School, and then worked with Yang Rui to conduct experiments on refined solanesol.

Regarding some key steps, Yang Rui still refuses to disclose, but the number is less than the previous time. After all, he is also a person who has the money to register patents.

The experiment of refined solanesol went very well, and Trapp gave a full score evaluation, which gave Zelecom and TCM Foreign Trade great confidence.

Director Hai and Frankie can't wait to sign the agreement with Yang Rui on the new joint venture plant.

Since Huarui Pharmaceutical Company is a Hong Kong company, the new joint venture factory has become a Sino-British-Hong Kong tripartite joint venture, and the big names are flying.

However, in order to minimize the trouble when choosing a crude solanesol factory, the three parties did not publicize the agreement to the outside world, but let the Director of the Sea negotiate with various companies first.

Although TCM Foreign Trade also has its own technical department, what they do is mainly foreign trade. If you understand the technology, it is impossible to be proficient in technology. So the director of the sea pulled Yang Rui and contacted each company separately.

Plant extraction method to produce solanesol, even if it is crude solanesol, it also needs thousands of tons of raw materials, and to supply a refined solanesol factory ~ www.readwn.com ~ at least three or more crude For the solanesol factory, more than five are naturally better.

All these investments need to be invested by TCM foreign trade. Of course, the profits generated by crude solanesol will also be shared by TCM foreign trade and related companies.

Since it was the money made by TCM's foreign trade, Director Hai took extra care and took the trouble to conduct in-depth exchanges with various companies. Not only that, he also sent people to Yunnan and other major tobacco provinces to learn about the local tobacco production and sales.

Regarding Yang Rui, Director Hai's attitude was extremely kind.

First of all, Yang Rui has won a certain political and economic status. It is a Huarui pharmaceutical company. Although the shell is like a leather bag company, it has multiple patents in it, and it will not be affected by anyone in any place in the country. Ignore. This year, it’s not that you can’t imagine that you can register a company in Hong Kong to be a Hong Kong-funded enterprise, but you can’t use foreign exchange to do this kind of thing.

Secondly, Director Hai has become more and more aware of the difficulty of producing coenzyme Q10 by semi-synthetic method. This is something that even the Beijing Institute of Biological Products cannot guarantee to make. Yang Rui has made it. Chief Hai feels great.

Third, it is because Director Hai really needs someone to help him judge the conditions for the construction of a crude solanesol factory. In this regard, foreigners are not credible, and his subordinates are very average, and Yang Rui has become the best choice.

Although he could not give Yang Rui a high reward, Director Hai did his best to serve Yang Rui comfortably, and the first thing he did was to move Yang Rui from the front building to the back building of the Pingjiang Hotel.

At the same time, smart local companies seem to have noticed something.