Rebirth of the God-level Xueba

　　 Su Xiankai became more and more proficient, and soon became an expert in bovine rhodopsin protein.

　　 Life in the laboratory is actually like this. When the laboratory just started deciding what to do, most of the participants actually had a black eye and could only learn by doing in the following research.

　　 This is probably not the same as ordinary people imagine, or it is completely different from industrial and political life.

　　 The most accustomed way of working in industry and politics, and repetition is about one of them. For example, in a private company, the employees he wants most are experienced employees. What kind of experience? Have done so-and-so projects, or familiar with so-and-so work, so as to facilitate repeated experience.

　　 But in academia, this is not the case.

　　 Except for some small laboratories or individuals who have been doing certain projects for many years, the requirements for the expansion of academia, or in other words, the requirements for opening up new fields, are much higher.

　　 Therefore, most academic researchers are actually in a state of lifelong learning and constantly trying new projects and new jobs.

　　 More advanced laboratories are even more so. Not to mention that they will always be cutting-edge science. They are always new things. Among these things, there are unavoidable familiar things, but inevitably there are also uncommon ones.

　　 Learn to do it when you are unfamiliar, read books or experiment and train yourself, and finally get familiar with it, a project may end, and then the cycle repeats.

Su Xiankai has never made bovine rhodopsin protein before, and there are not many in the world. If you talk about learning, there is no place to learn. It is good to teach two or three kinds of protein in the school. If you teach each kind, not to mention the textbook. Can it be compiled? Without a life span of 800 years, this kind of thing doesn't need to be considered.

　　 However, it is the most common situation that you have to do it if you have not learned it.

　　 One of the effects of repeated experiments is also a high learning efficiency. If it is a late follower laboratory, training soldiers through various repeated experiments is the most cost-effective.

　　 Of course, pondering and learning are also directional.

　　 If there is no restriction from Yang Rui, Su Xiankai's learning direction is more in-depth study of bovine rhodopsin protein itself to understand its working mechanism and effect.

　　 However, Yang Rui's order is simply tiresome.

　　 is always a simple increase in production.

　　 Increase production when it doubles.

　　 Increase production when five times.

When 　　 was ten times, the order was actually to increase production.

　　 Su Xiankai's research direction can only increase production continuously.

　　 For biologists, increasing production has never been a mysterious topic, the smaller the unit, the more so. For example, penicillin, which is often used as an example, in the early 1950s, China’s output was tens of kilograms, so that 20,000 units of penicillin sold for one or two gold. By the 1980s, China’s penicillin output How much is it? Hundreds... The unit is tons, and the patient-oriented pricing has dropped to one or two cents per bottle.

　　Without him, the production of penicillin was rolling upwards.

　　 Bovine rhodopsin protein is essentially the same as penicillin.

　　 is even very similar to the coenzyme q1o that Yang Rui had originally made.

　　 Once, when Yang Rui was in the Xibao Meat Factory, the production method of coenzyme q1o was tissue extraction method, that is, a little bit of pig heart and beef heart were stirred and broken, and then the desired coenzyme q1o was extracted by various means.

　　 Later, including the Xibao Meat Union Factory, improved their plans and adopted plant extraction methods, which greatly reduced production costs. Later semi-microbial extraction plans, and even fully synthetic extraction plans, are also options that can be made with technological progress.

　　 Bovine rhodopsin protein is currently the only option for tissue extraction.

　　 However, compared to products such as coenzyme q1o, research materials such as bovine rhodopsin protein do not need to be too costly.

Su Xiankai asked for an increase in the supply of fresh bull's eyes, and at the same time began to slowly change the solution used for extraction, and even adopted re-extraction measures... Speaking of specific details, it is naturally very complicated, but in essence it is quite simple. The oil is almost the same, one is to increase the total amount of extract, and the other is to reduce the loss.

　　 Moreover, just like the refining process of oil extraction, bovine rhodopsin protein also needs a purification process.

　　 It took almost a month for Su Xiankai to finally enter the fast lane.

　　The increase in output has also increased from ten times to 5o times.

　　In this way, the ion channel laboratory of Peking University has officially entered a node-the output of raw materials has finally passed the consumption.

　　 Gu Qiang, Fan Zhenlong and Wang Sisheng, plus two scientific research dogs, although they were busy, but after all, the five of them could not consume so much bovine rhodopsin protein.

Regarding this, Yang Rui would naturally not let it go, and forcedly ordered: "This week I will give you a buffer time. Everyone will work overtime to use up the bovine rhodopsin protein made by Lao Su's group. Starting next week, I hope you think of a better way to speed up the experiment process."

　　The faster the experiment progresses, the greater the consumption of raw materials. Of course, there are some crooked ways, but this is not done in such a small laboratory.

　　 Fan Zhenlong bitterly said that the baby could not do it, or he would add someone to the baby.

　　Yang Rui said with no sympathy: "It is only the better-performing group that increases manpower. The progress on your side is obviously slowing down. This cannot be solved by increasing manpower. On the contrary, you have to find ways to improve efficiency."

　　 Gu Qiang, Fan Zhenlong, and Wang Sisheng, together with two scientific research dogs, had to work overtime in a proper way.

　　 However, they work overtime

In any case, the time is not as good as Su Xiankai.

　　 In order to achieve 1oo times the production capacity, Su Xiankai has long been freed from the 11o-hour work system. He works more than 13o hours a week, and occasionally if he only works 15 hours a day, he will be excited and unable to sleep.

　　 The output of raw materials has come up, and the follow-up experimental group had to follow through desperately.

The conformation of the transmembrane region of the 　　 g protein-coupled receptor has finally been raised step by step.

　　To obtain a high-resolution three-dimensional structure, it means three steps like this.

　　 The first step is to have a conformation.

The 　　 conformation is an exclusive term in organic chemistry. It is a high-end version of hydrogen dioxide. In space, it indicates where the hydrogen is and where the oxygen is, and it is best to have an angle between each other.

　　 The second step is to obtain the crystal structure.

　　 The third step is to obtain a high-resolution three-dimensional structure.

　　 Any one of these three steps is an S-level result that can cause a sensation.

　　 In fact, apart from Yang Rui, the goals of other international laboratories are only one step.

　　 No one wants to complete three steps at once, or even further study the signal problem.

Because of these three steps, except for the first step which is slightly reluctant, each step is the result of a possible Nobel Prize~www.readwn.com~Who would give up such a huge temptation to study the next step in secret What?

　　 However, the temptation to come to three conclusions is beyond doubt.

Assuming that the Nobel Prize is awarded to the three-dimensional structure of the g protein-coupled receptor, those who are eligible to accept the award should include the person who completed the second step of the crystal structure, the person who completed the third part of the three-dimensional structure, and the subsequent signal transmission If one of the three completed the first step at the same time, then there is no doubt that he will be the number one scholar. If Sany completes it together, it is possible to win the prize alone.

　　 Of course, since the 1970s, there have been fewer and fewer Nobel prizes awarded individually. They even tried to combine two unrelated achievements together in order to satisfy the number of three people.

　　 is really the number of people eligible to win the Nobel Prize, which has greatly increased in these years.

　　 However, g protein-coupled receptors are still a strong field. If anyone can win the Nobel Prize alone, it can only be such a project.

　　 Although Yang Rui knew that it was impossible, he still didn't want to give up at the beginning.

　　 After all, foreign laboratories are not yet strong. The ion channel laboratory of Peking University still has some opportunities. Even if they are very small, they can still be called opportunities.

　　 Besides, if it's trivial, the idea of ​​g-protein coupled receptor is trivial in itself, let alone the subsequent steps.

　　……