I Kidnapped An Alien Civilization

2021-07-07

Chapter 129 Begins the test

Small Conference Hall, Li Mo sat at the conference table with two whiteboards behind him.

“The biological samples have been delivered this morning and are now being stored in the incubator.”

“There are 10 groups of samples, and I need you to detect the neuronal tissue samples of the gradually frozen patients. Does it contain biological toxins?” Li Mo said and stood up, writing the words “biological toxins” on the whiteboard behind him.

“Bacterial toxins, mycotoxins, animal toxins or marine biological toxins?” Zhou Fang frowned asked, “What type of biological toxins, toxins that can cause photosensitivity reactions, or toxins that cause neurological disease ?”

“Is there a specific target site?”

Good question, Li Mo nods, it seems that Zhou Fang has done some research in this area.

He took out the printed materials and distributed them to 5 people. Said: “According to my analysis, the cause of ALS is likely to be a biological toxin produced by the human body itself.”

“Does the human body produce toxins?” Wang Qian raised her hand and asked.

Before Li Mo could answer, Zhang Xueming next to him touched his thinning hair and said, “Aren’t free radicals and uric acid just toxins produced by the human body?” Li Mo watched him skillfully when touching his hair. At this time, Zhou Fang, who has researched on toxins, said, “Strictly speaking, free radicals and uric acid are not biological toxins, they are only human body. The harmful substances produced in the normal metabolism process, I think the biological toxins mentioned by the boss are not referring to this.”

Li Mo’s nod said: “This time to find biological toxins is a It is an active substance that is produced by the human body itself and can cause harm to human motor cells.”

“At present, the production principle of this biological toxin is unknown, the structure of the compound is unknown, and the specific target site is unknown. We need you to find out by comparing the neuron organization of normal people through biological dissection experiments.” Li Mo threw out the unknown triple.

This task can be described as more difficult, and there is no clear goal, only a general scope. It’s equivalent to finding a needle in a haystack.

He thought that the 5 people present would complain a lot, didn’t expect Wang Qian, who was lively and lively, to say first: “The boss is the boss, so he set up such a difficult experimental task as soon as he came up.”

Zhou Fang also said with bright eyes: “Boss, no matter what the results of the experiment are, I will give you the idea that the human body will also produce biological toxins. I have to give you a thumbs up.”

Every scientist has a desire to challenge the future. When the five researchers heard the task assigned by Li Mo, they not only did not lose confidence because of the difficulty, but also actively discussed the experimental plan.

“I propose to use the mass spectrometry detection method for detection first. The detection range of the mass spectrometry method is wide.” Zhou Fang lifted his eyes and said.

“Second, mass spectrometry is the most stable.”

“Second.”

Soon, everyone reached a consensus that mass spectrometry was used for the first detection.

“Then everyone will start the experiment now, first remember to wear protective clothing. If this toxin really exists, we currently don’t know its specific attribute, so you must pay attention to safety when dissection. “Li Mo said.

Wang Qian pouted Li Mo and gave a salute: “Don’t worry Boss, we are veterans of battle.”

The mass spectrometer used in the biological laboratory It is a matrix-assisted laser desorption time-of-flight mass spectrometer that needs to record the exact mass of the sample. Zhou Fang, wearing a biochemical protective suit, carefully took out the biological sample and placed it on the laboratory bench. Zhang Xueming took the LITTLE test tube, took a little sample, put it into the high-speed centrifuge, and started the centrifuge.

Wang Qian put the 0.1g biological sample into the mass spectrometer, set the detection program, and the mass spectrometer issued a beeping sound of “di di di di”.

Li Mo knows that in the mass spectrometer, there is a co-crystal film formed by a laser irradiating the sample and the matrix, the matrix absorbs energy from the laser, and the charge transfer occurs between the matrix and the sample to ionize the sample molecules, and the ionized sample Under the action of the electric field, it is accelerated to fly through the flight pipe, and it is detected according to the different flight time to the detector, that is, the ratio of the mass to the charge of the measured ion is proportional to the flight time of the ion to detect the ion.

MALDI-TOF-MS is currently the most effective method for detecting protein macromolecules. It can detect peptide mass fingerprint (PMF), post-source fragmentation (PSD) fragment ion spectrum, and Combined with mass spectrometry network database search, the sequences of peptides and proteins can be obtained.

Zhang Feng next to the test bench input the data during the experiment into the computer.

The mass spectrometer takes 2 hours for each detection, and everyone started to make samples of the control group in their spare time.

Li Mo stood in front of the glass window of the office and looked at the researchers working meticulously in front of him, and his heart was full of relief. The technical strength of New Generation’s researchers is still very strong, but it lacks a suitable platform.

The experimental data of the first group was released soon, and Zhang Feng passed the data to Li Mo through the computer. Li Mo opened the data and started the analysis. The data showed that both groups of biological samples contained casein, keratin, albumin, globulin, hard protein, protamine, histone, structural protein and acetylcholine, while the data in the control group contained more aldehyde dehydrogenase.

Useless, useless! Li Mo looked at the data of the first group and looked at the head helplessly. The only difference in acetaldehyde dehydrogenase can only indicate that the provider of this biological sample is very good at drinking. The main function of acetaldehyde dehydrogenase is acetaldehyde, the oxidation product of ethanol.

However, a set of data has only been carried out now, and he does not expect to find unknown biological toxins soon.

“BOSS, it’s noon, do you want the researchers to get off work first?” Xia Qing saw that Li Mo was focusing on analyzing the data in the computer. Knowing that he had forgotten the time again, Xia Qing reminded her.

Li Mo realized that a morning had passed. He asked: “Have the experimental data of the second group come out?”

Xia Qing replied: “Not yet, it is estimated that it will take another hour, and I can’t understand the biological experiment.”

It will take another hour for the second group biological experiment data to come out, but there are still 8 groups of samples waiting to be tested. Biological experiments are like looking for a needle in a haystack. Through enough comparison samples, the biological toxin is finally captured.

Thinking of this, Li Mo shook the head, “Help everyone order takeout, and ask for the best. Inform everyone that you can take a 30-minute break at noon.”

When Xia Qing told the news When the researchers were outside, Wang Qian was the first to say, “I want boiled pork slices, it’s spicy.”

Eating meat in front of biological samples, no wonder some people say that biological girls can’t afford to offend. Li Mo shook the head and continued to sit back in front of the computer.

“Boss, what do you want to eat?” Xia Qing asked as she pushed open the door.

Li Mo didn’t need to eat after taking the energy coffee, but he still ordered a lotus seed egg porridge.

(End of this chapter)