I can extract side effects

"What kind of rare blood type alliance sent Sanqing a "RH Negative Artificial Blood Research and Development Proposal"?"

As soon as Wei Kang arrived at the office, he learned a piece of news that made him dumbfounded.

"The Rare Blood Type Alliance has branches in various provinces and cities, with many members. There are more than 80,000 members nationwide. They are very active in participating in various blood donation activities, so they have a great influence in society."

The director of the administration department respectfully handed over a document in his hand, and said, "The directors of Haishi, Suzhou Province, Zhejiang Province, Kunming City and other regions came to the door together to submit proposals to Sanqing. This public opinion The power cannot be underestimated.”

Wei Kang took it, put it on the table casually, frowned and said: "They have a good idea, but our artificial blood project is very tight in time, and I am afraid it will be difficult to meet their needs."

"Of course, they are also willing to pay for this. If Sanqing is willing, tens of thousands of members of rare blood types across the country will voluntarily participate in clinical trials for free, and provide all conveniences for research and development, such as extracting hematopoietic stem cells." The executive director added.

"Well, since they are so sincere, they can think about it." Hearing this, Wei Kang's heart suddenly moved, and he quickly changed his words.

He thought of the thousands of volunteers needed for clinical trials of human blood.

Generally speaking, when pharmaceutical companies conduct drug clinical trials, only terminally ill patients are most willing to participate, and they do not need any monetary incentives.

For other diseases, more or less money is required to recruit drug testers.

Some impoverished people even regard drug testers as a profession to make ends meet.

Projects such as artificial blood do not treat diseases in the first place, but only to test the safety of the human body. Therefore, Sanqing has to pay each drug tester 5,000 yuan to recruit enough people.

In this way, the compliance of many experimenters is not very good. After receiving the money for the first blood transfusion, the follow-up reexamination is not very active, and they often push back and forth.

As for getting them to cooperate with other inspections, it is even more difficult.

Therefore, if it is replaced by a rare blood type volunteer with a positive attitude and free participation, it will naturally be easier to use than ordinary people.

Not only can tens of millions of expenses be saved, but also there is no need to worry about the patient not coming back after the blood transfusion.

"In addition, this research and development proposal has also received the attention of the Provincial Blood Center."

"Director Huang also called to express his support for the research and development of RH-negative blood, and was willing to provide all conveniences for clinical trials."

"That's it." Wei Kang fell silent for a moment. It seems that this rare blood type alliance must meet to see what their specific needs are.

The next day, he met a group of people from the Rare Blood Type Alliance in the meeting room, along with Director Huang.

"Director Huang, it's a pleasure to meet you!"

"Haha, seeing Mr. Wei today, he is indeed young and promising, and his reputation is well-deserved!"

"Mr. Wei, hello, I'm Xie Tianyin, the director of Haishi Branch."

"I'm Chang Hao from Suzhou Branch."

"I'm Lin Xi from the Zhejiang branch."

"Hi everyone, please sit down."

The three parties greeted each other for a while, and then sat down.

Wei Kang looked across and asked curiously: "Can you tell me about the donation? Only then can I learn more about RH negative blood."

"Hehe, it's what it should be." Xie Tianyin laughed. He looked at the other two, exchanged glances with each other, and was the first to speak.

"Actually, we all found out that we have panda blood by accident, and when we first found out, we were still in a state of 'confused'."

"However, many of us are lucky because we knew our own situation before the danger happened and found the organization in advance, but luck does not favor everyone."

"Actually, I have seen many tragedies in the past ten years I participated in the rescue." Xie Tianyin said with some emotion: "In fact, panda blood is the same as normal people. The only predicament is the lack of blood source. As long as there is enough blood, you There will be no tragedy."

"Donating blood twice a year has become a habit I have persisted in for twelve years. The blood that flows in my body every day is nothing ordinary, but for those who need it, it is hard to find, and it is better than countless miracle medicines. "

Xie Tianyin recalled: "Many years ago, I saw a child who had just undergone chemotherapy for leukemia and was waiting for a blood transfusion. He was so weak that he didn't have the strength to move his arms. But as long as the blood transfusion was finished, he could be alive and kicking that night, just like ordinary people."

He smiled a little embarrassedly: "I don't have much professional knowledge. At that moment, I felt very miraculous. I felt that blood is the most sacred thing in the human body. If I can devote myself to such a career, I will die without regret."

"There is no story behind it. At the first time or two, my heart was full of excitement, and I felt that I was very amazing in saving people. After a long time, I felt like eating and sleeping. I really didn't feel anything."

The other two immediately laughed heartily, nodded in agreement, and joined the discussion.

"In fact, the rescue has been very successful for so many years. Every year, new people join in. They come from all walks of life, and many of them have received rescue and joined the team after recovery."

"We know very well that individual and collective abilities are limited. We will age and get sick. The only way to keep the blood source alive is to let young 'panda blood' join in."

"Love can be passed on, influenced, and diffused. When enough people have this awareness of donating blood, panda blood will no longer be in trouble."

"Humans are animals that are born in sorrow and die in peace. It is the scarcity of panda blood that awakens us to help each other."

"Many of us are aware of the possible suffering in the future, choose to organize, join groups, donate, and spontaneously form a mutual aid group to solve part of the problem. This is the power of human wisdom."

Wei Kang couldn't help but nodded and said: "So now you see artificial blood coming to your door, it is also based on this sense of urgency."

"That's right." The three said in unison: "In fact, when I saw the news of artificial blood, I knew that the road of free donation may never go on, because human beings have found a better way." Method."

"As I said just now, new volunteers join every year, but there is another point, old volunteers leave every year."

"It's good that they didn't join this circle. Once they join, they will inevitably encounter information about paid donations. Many people can't resist this temptation."

"'Panda blood' is scarce in success and failure. Because it is too precious, the price in the market is much higher than that of ordinary blood. It is beyond the imagination of ordinary people. It is difficult for ordinary people to refuse this temptation."

"When some volunteers have donated blood for a fee, it is difficult to accept unpaid blood donation, and they often choose to leave."

"Maybe it's not obvious now, but over time, there will be fewer and fewer donors. So we have to find a new way out."

Wei Kang asked: "How much is the price of illegal channels for panda blood?"

Xie Tianyin said with a wry smile: "General RH-negative blood is about 20,000 yuan for 400ml. If it is the rarest blood like RH-AB, 400ml can be sold for 50,000 yuan. No one can ignore such a price, and resist the temptation purely by conscience." , because there will always be times when you need money.”

"You know, 200 milliliters of ordinary ABO blood is only a thousand dollars at most."

"It can be said that a person with panda blood is a walking ATM machine."

"When our members travel abroad, I always tell them to be careful, don't reveal that they are Rh-negative blood, otherwise they may be in danger."

Wei Kang frowned. This phenomenon of buying and selling blood as a resource made him feel deeply uncomfortable.

A wave of anger surged into my heart in an instant: "These traffickers are going too far to treat human blood as a resource."

He has never had a strong desire to end this chaos like he did at this moment.

For human beings, whether it is blood or organs, under no circumstances should be regarded as a resource.

The fact that the panda's blood was trafficked completely triggered his rebellion.

At this moment, he has already made a decision that even if artificial blood is to be mass-produced, the priority of rare blood types must be given top priority.

"Blood is being traded as a resource. This is unacceptable to me. I am willing to pay any price to eliminate this chaos."

Wei Kang said in a deep voice: "So no matter what the purpose of your coming, I will agree. This is not difficult for Sanqing."

"In fact, if you are willing to provide hematopoietic stem cells directly, the manufacturing process will be simpler and faster than ordinary artificial blood."

"Before the official launch, Sanqing will provide a batch of fresh RH-negative blood every month at the market price of ordinary blood, and reserve it in the blood center. What do you think?"

"In this case, plus your donation, it should be able to achieve double the protection effect."

"I hope that after the artificial blood is officially launched, the underground blood black market can be completely wiped out."

The three of Xie Tianyin were overjoyed and said: "Thank you very much. If there is no demand, there will naturally be no business. Mr. Wei, your goal will be achieved as soon as possible."

"The three of us can draw a tube of hematopoietic stem cells each, and leave after we finish." Lin Xi rolled up his sleeves, looking impatient.

Director Huang finally spoke out: "I would like to thank Mr. Wei on behalf of the blood center. As long as artificial blood is popularized and there will be no more blood shortages in blood banks, I can guarantee that illegal blood trading incidents will completely disappear."

He represents the attitude of the above, and his words are very convincing.

Wei Kang couldn't help laughing: "Let's do this, it's not too late. It's better to hit the sun than to choose the day. The three of you go to the laboratory to draw blood first."

"Okay!" The three of them stood up without asking any further questions.

Director Huang saw that the matter was going very smoothly, so he waved goodbye immediately.

The three of Xie Tianyin were left in the conference room, continuing to discuss with excitement on their faces.

Wei Kang called the stem cell laboratory and arranged for the blood to be drawn, and explained with a smile.

"You don't need to be afraid. Donating hematopoietic stem cells now only needs to draw blood, which is very convenient and doesn't need to be as painful as drawing bone marrow before."

"It is mainly carried out by drawing venous blood. First, inject granulocyte colony stimulating factor to concentrate hematopoietic stem cells into peripheral blood, and then perform venipuncture to extract venous blood for processing and isolate hematopoietic stem cells."

"Of course the separation step will take a little longer, about 3-5 hours, but don't worry, the whole process feels similar to donating blood, but it takes a little longer. Remember to pay more attention to rest and strengthen nutrition when you go back."

Xie Tianyin nodded and said, "It's okay, I'm already familiar with donating blood. Fortunately, it was 6 months ago that I donated blood last time, so collecting hematopoietic stem cells this time will not affect it."

Chang Hao hesitated for a moment, and said, "It hasn't been more than 6 months since I donated blood last time, why don't I contact my group of friends and ask someone else to come over?"

Lin Xi also said worriedly: "Should we make up four people, and make up A, B, O, and AB four RH negatives, so that we won't be afraid of lacking any blood type."

Wei Kang chuckled: "ABO blood type is not important. Our technology can remove this restriction, as long as it is RH negative. Sanqing's employees are only RH positive, so the previous artificial blood cannot produce RH negative. , If genetic modification is to be performed to remove the D antigen on red blood cells, unnecessary steps will be added and the success rate will be reduced.”

"So it's better to use your hematopoietic stem cells, complete the predetermined genetic modification, and then proliferate in vitro to produce artificial blood."

In fact, there are more than 30 antigen-related depressions on the red blood cell membrane, and hundreds of antigens related to blood type are inserted in it. It is impossible to remove all of them. Only the most influential antigens, namely A and B, can be removed. and H antigen.

Even if the D antigen needs to be genetically modified and removed, it is not as convenient and quick as using RH negative blood directly from the source.

"No problem." The three of them breathed a sigh of relief. If the Rh-negative artificial blood can not be limited to the ABO blood type, it will definitely be a great joy for them.

About ten minutes later, a young man wearing glasses hurried in.

"Ding Mian," Wei Kang beckoned: "This is the client I told you about. You take it to the laboratory to extract some hematopoietic stem cells, and then do as I said."

"Mr. Wei, okay, I'll take them there right away, the granulocyte colony stimulating factor is ready." Ding Mian walked over, showing a bright smile on his face.

"This is Ding Mian, he is in charge of the artificial blood project." Wei Kang introduced Ding Mian to the three visitors.

"Wow, so young and promising? It looks like he's only in his early 20s." Xie Tianyin and the others were stunned.

It never occurred to them that the so-called head of the laboratory turned out to be a young man. According to their assumptions, he should be a kind-hearted old expert in his fifties.

Immediately, he had a new understanding of the age of Sanqing Group from top to bottom.

"Three, please come with me." Ding Mian smiled and stretched out his hand in the direction of the gate.

Soon, he brought the three of Xie Tianyin to the laboratory, extracted two tubes of hematopoietic stem cells according to the procedure, and put them into the freezer.

"Within three days, the genetic modification can be completed, and then a large amount of self-proliferation in vitro will take about a week, and finally it will be officially transformed into blood, which will take another week."

"At most 18 days, you can provide RH negative blood." Ding Mian explained: "I will contact you at that time and provide the blood to the blood bank."

The three were stunned again: "Is it so fast? Don't we need to do anything else?"

"I don't need anything else, but the clinical trials for RH-negative blood require more active participation of your members."

The three of them nodded again and again: "That's what it should be, thank you so much, brother, you are so young, do you have a girlfriend? There are many beauties in our group, I can introduce you. You are so young and handsome, you must be very popular with girls welcome."

Ding Mian's face turned black immediately: "I made blood for you, but you are greedy for my body."

He quickly shook his head and said, "I'm only 20 years old, still too young, a man, I must start a career before starting a family, besides, I'm usually too busy with work, so I don't have time to fall in love."

"Oh, that's right, it's true, it can't affect your work."

When the three of them heard this, they didn't insist anymore, and asked some questions related to artificial blood, and then they all left.

Recently, I have been coughing every day, and my lung tubes are almost coming out, and then my chest hurts badly, and I am still weak, so the update is not effective, forgive me!

It is said that it takes two or three weeks for the cough to subside. I hope it will get better after New Year's Day.