Hello 1983

  Chapter 752 Success, we succeeded!

  Liu Qingshan really has this idea to poach the wall. As Jiapigou and Liu Qingshan's own industries become more and more, the talent gap is getting bigger and bigger.

  However, Professor Zhong did not mean to criticize Liu Qingshan. If their students chose to stay, he and Professor Zhang would not stop them.

   Even they also have the idea of ​​joining Jiapigou Pharmaceutical Factory, especially Professor Zhong, who has retired now and was hired back to continue to exert his residual heat.

   After the dividend meeting ended and the guests were sent away, Liu Qingshan had time to go to his eldest brother-in-law.

  When I entered the room, I saw three writers sitting there drinking tea and chatting. It seemed that the conversation was very speculative.

  Among the three, Writer Lu is the head, followed by Gao Wenxue, and Writer Yu is currently the most junior.

  Writer Yu was also very envious when he heard that the works of those two had been published abroad, and they had also received a lot of remuneration.

  When Liu Qingshan came in, the three of them were discussing this topic.

  Liu Qingshan smiled and said: "Brother Yu, if there is a chance in the future, you can also translate your works."

   Later, he was alive and won the French Order of Knights, of course he has this qualification.

  Yu Hua waved his hand a little awkwardly: "I am still a little far away from Brother Wang and Brother Gao."

  Liu Qingshan also sat down next to him: "Brother Yu, you have just entered the golden period of creation, and you are short of a masterpiece. Do you have any ideas recently?"

   "I do have an idea. I discussed it with Brother Wang and the others just now."

  Writer Yu didn't hide anything, so he just talked about one of his thoughts.

  He wants to write about a person who has lived tenaciously through the great era. All the relatives in his life have left him, and in the end only an old cow is left to accompany him.

   Liu Qingshan couldn't help but his eyes lit up: Isn't this the one that is alive?

   It is about living, but it is farewell to death again and again. It is about the ability of human beings to face suffering and the meaning of life.

   So Liu Qingshan couldn't help asking: "Several writers, I want to hear your opinions on why people live?"

  This question is about to rise to the level of philosophy, so the three writers are all in deep thought.

  Writer Lu lit a cigarette, smoked it quietly, and said in an unhurried tone:

"Thinking about it, everyone's life is also a world. Even the most ordinary person has to fight for the existence of his world. In this sense, in these ordinary worlds, no one is ordinary of."

  “I am alive, so I have to work like a cow and dedicate like the land.”

  In the curling smoke, Writer Lu expounded his understanding of life, and the other three people in the room couldn't help awe.

  Even the most ordinary person has to fight for the existence of his world, this is the meaning of life.

Gao Wenxue also rolled a cigarette: "I think people should live for the beliefs in their hearts. Your beliefs can be to make your family and yourself live better, or to make society and the country better." it is good."

  "If you have faith, you will not live in vain."

  The other three people also nodded.

  Finally, everyone looked at Writer Yu, but he shyly shook his head:

   "I haven't figured it out yet, maybe when I figure it out, I can start writing this novel."

  Writers Lu and Gao were not disappointed, because they are all experienced, and they know the importance of this point to creation, it is a soul-like existence.

   "Qingshan, what do you think?" Writer Lu suddenly threw back the question.

he?

  Writer Yu was a little surprised. In his opinion, this is something writers should think about. As far as he knows, Liu Qingshan is just a businessman.

  Businessmen value profits. Although Liu Qingshan doesn't have the smell of copper, Writer Yu doesn't think that the other party has this qualification.

   Perhaps seeing Writer Yu's expression, Writer Lu smiled slightly:

   "Actually, the sum of the manuscript fees of the few of us can't keep up with the fraction of Qingshan's manuscript fee."

  Writer Yu couldn't help blinking hard: "Mr. Liu, are you also a writer?"

  If it were an ordinary person, I'm afraid they wouldn't ask so directly, but most writers have their own personalities.

   Of course Liu Qingshan doesn't care: "I mainly cooperate with others, and most of them are published abroad."

Now, Writer Yu was even more shocked: "I also came into contact with a large number of works by foreign writers in the Faculty of Arts, such as Walden Pond, One Hundred Years of Solitude, etc. By the way, there is also a recent book The Shepherd Boy's Fantastic Journey that is also worth reading. "

  The corners of Liu Qingshan's mouth twitched slightly: "When I published books abroad, I used the name Mountain."

  Whoosh, Writer Yu stood up all of a sudden, he stood a little dazed, touched the table, and the tea in the teacup dangled out:

   "You, you are Mountain?!"

  Writer Yu's eyes shone with a strange light.

  He finally understands now: Among the four people present, he is indeed the weakest one.

  A sense of powerlessness surged into Writer Yu's heart, but it was quickly replaced by a strong unwillingness, and the energy of not admitting defeat in his bones was completely aroused.

  Liu Qingshan fetched a rag, wiped the table, and said while wiping: "I think that life is an instinct."

   "Just like a small grass, a big tree, a butterfly, or a tiger, survival is an instinct."

   With a snap, Writer Yu slammed his fist hard. He found inspiration in an instant, and shouted excitedly:

  “That’s right, people live for living itself, not for anything other than living.”

   Tossing and turning, muttering several times in his mouth, and then suddenly grabbed Liu Qingshan's hand:

   "Thank you, thank you, let me grasp the soul of this work at once!"

  Gao Wenxue next to him looked at this familiar scene with a smile, because he had a personal feeling: Qingshan is such a person who can get into the soul at once.

  After the excitement, Writer Yu sat down again, the excitement and excitement on his face were still hard to calm down:

   "Maybe I am not eligible to receive the Jiapigou Literature Award, but please believe me, when my new work comes out, I will definitely be eligible."

  Liu Qingshan also nodded with a smile, of course he believed it.

  The next day is Xiaonianer, and of course I eat dumplings in the morning.

   Liu Qingshan rushed to the pharmaceutical factory early after eating, because trial production will be carried out today.

  Everyone is also very concerned about this research, and as a result, a lot of people went to it.

  When we arrived at Jiapigou Pharmaceutical Factory, we were eating dumplings there.

  The main reason is that there are many people who eat dumplings and few people who make dumplings. This is because Professor Zhong and the others are all hands-on.

  Those foreigners also like dumplings very much.

   "Liu, have you eaten?"

  Foreigners also went to do as the Romans did, and greeted Liu Qingshan in such a language full of Chinese characteristics.

   "Liu, try one. It's stuffed with vegetables. It's very refreshing."

  Mason's ears were wrapped with white gauze, and he skillfully picked up a sauerkraut dumpling with chopsticks.

   Wait for everyone to finish eating and change into work clothes before going to the workshop.

  The raw materials have been shipped, twenty kilograms of dried yew seeds, quietly packed in a large glass jar.

  At such a critical moment, everyone's heart can't help but become nervous, Kevin said:

   "Paclitaxel is the most abundant in the bark of the yew. If the bark of the yew is used, it takes about 13.6 kilograms of bark to extract 1 gram of paclitaxel."

   "I don't know how much paclitaxel can be contained in the yew seeds here?"

   This is also the issue that everyone is most concerned about, and no one knows what to do.

  The reason why the drug paclitaxel is so precious is that the yield is too low, and the bark of the yew is relatively thin. How much bark can a tree produce?

  Treating a patient requires the bark of several yew trees, which are scarce and grow slowly.

   Cutting down trees and peeling the bark to extract yew trees will be criticized by environmentalists.

  The superimposition of various reasons has caused the preciousness of paclitaxel.

   "Let's get started, I hope we can make a miracle."

  Liu Qingshan waved his hand, he is very confident in the local yew, because it has been proved later.

  These technicians began to perform their duties, and as the equipment was turned on, there was a humming sound in the workshop.

  The laymen who came to visit all looked solemn, because they also knew the significance of this experiment.

   Extracting paclitaxel is a very complicated process, because the structure of paclitaxel belongs to a tricyclic diterpene compound, and its structure is extremely complex.

   There are also scientists who want to synthesize it artificially, and they did succeed in living a few years later.

  The reagents and materials needed are expensive, and it is impossible to achieve large-scale mass production.

  Later, a semi-synthetic method was developed, using a fir tree similar to the yew tree to synthesize paclitaxel. The process is also relatively complicated, so the price of paclitaxel has not dropped much.

   The waiting process was a bit boring, so the fourth brother proposed to lead those singers to visit Daji in the countryside.

  This idea was immediately welcomed, so everyone covered up tightly, and happily followed the fourth and fifth.

   "Little stool, don't go, I have something to do with you." Liu Qingshan yelled.

  Xiao Stool likes to join in the fun, and immediately started pouting, and then heard Liu Qingshan continue to say: "I found a suitable song for you."

  Wow, the little stool screamed strangely, and rushed towards Liu Qingshan.

  Who doesn't know in Dashuxia Company, the songs created by Mr. Liu are basically classics, who doesn't want it?

  Others also stopped, looking enviously at the small stool.

  The fourth child was a little dissatisfied: "Brother, are you robbing me?"

  Liu Qingshan waved his hand: "Everyone go for a walk first, I just find a small stool to try it out first, if possible, everyone can participate."

  Everyone couldn't help but be overjoyed: Is this the rhythm of holding a concert of 100 singers?

  So they all followed the little brother, happily running away without a trace.

  But there were also those who didn’t go, Amao didn’t like to join in the fun, so he also stayed.

  It happened that Liu Qingshan also needed her, so he led the two girls, one older and one younger, into the activity room of the pharmaceutical factory.

   It wasn't until the market ended at noon that Xiao Lao Si led the large team back with a full load.

  These singers held candied haws in their hands, and some held large candies, all of them were very happy.

   And even more gratifying news came from the workshop: Paclitaxel has been extracted!

  As soon as everyone heard this, they all rushed into the workshop. When Liu Qingshan rushed in, they saw the technician named Karl holding a small test tube with half a white crystal in it.

   After weighing, Carl's face also turned red: "Oh, it's 30.5 grams in total!"

   "We used 20 kilograms of yew seeds to extract 30.5 grams of paclitaxel, and the content reached 0.15%, which is unbelievable!"

   Laymen don’t understand, but these experts know that even the bark of Taxus brevifolia, which is recognized as having the highest content, contains only 0.069% of paclitaxel.

   And don't underestimate the 30 grams of paclitaxel. Judging from the current market price, it is worth nearly 10,000 US dollars.

   "Is there something wrong?"

  Kevin did not follow the excitement, but suspected that there was a problem in some link, and the extracted product was not paclitaxel.

   "It has been tested, and it is indeed paclitaxel crystals." Carl was very dissatisfied with Kevin's suspicion.

  Although he was also shocked, what shocked him was that the yew seeds here had such a high paclitaxel content.

   But you can't question his professionalism.

   "Success, we have succeeded!" In the workshop, cheers rang out.

  The members of this temporary team hugged each other, with smiles blooming on everyone's faces.

  Kevin was also elated: There are a total of tens of thousands of catties of yew seeds. According to this ratio, dozens of kilograms of paclitaxel can be extracted, which is also worth several million dollars!

"I'm coming!"

  Lv Xiaolong just picked up the bearded principal in a jeep, and this guy was still bluffing: "It's better to come early than to come. It's just made, and it's still hot. Give it to our Principal Xu while it's hot!"

   You thought it was a bun just out of the drawer, paclitaxel is very toxic, and the dosage must be carefully calculated.

   Moreover, this substance is insoluble in water, and it is troublesome to inject, and it is easy to cause allergic reactions. First, inject dexamethasone or the like to adapt.

  In fact, until this year, the clinical trial of paclitaxel has only entered the second phase, and it will not be gradually perfected until the 1990s.

  Principal Xu was a little puzzled when he saw the situation, just like Liu Qingshan asked:

   "I'm afraid this thing is quite expensive, I'd better not use it, I feel pretty good now."

  Liu Qingshan was about to lie and say it was the price of cabbage, but the little boy next to him spoke quickly:

   "Uncle Xu, of course it's expensive, just a little bit, it's worth ten thousand dollars."

  The bearded principal waved his hands again and again: "No, no, no, it's not worth the price if you sell me."

   It made Liu Qingshan a little headache, he knew Principal Xu's temper, and he had the stubbornness of a scholar in his bones.

   So Liu Qingshan could only say: "Principal, this thing is not in vain, you have to cooperate with clinical trials."

  Principal Xu was also overjoyed: "You're using me as a guinea pig, right? Then it won't work."

  Of course he understood Liu Qingshan's kindness in his heart, but he really couldn't use such a valuable thing.

   There is no way, Liu Qingshan can only wave to Amao, it is time for her to come out and persuade the bearded principal.

   Of course, Amao played to her strengths and began to sing the song Liu Qingshan taught her just now.

  (end of this chapter)