Black Technology Library

Chapter 85 M1 Live Experiment
This part of the experiment needs to be carried out at the animal level.The results of cell experiments and the results of live animal experiments can sometimes be very different.The purpose of this step is to determine the effectiveness and safety of the drug.

"Are you sure that the results of your new drug in live animal experiments are exactly the same as the results of cell experiments?"

"It must be the same. How could I make such a mistake? Come on, Lao Zhao, we have to report as soon as possible. The Shangshengyuan is also working on the universality of the m1 virus. If it is one minute late, the cooked duck will be gone." Fly!"

"I said Pan Yan, this is not a trivial matter, a scientific experiment..." Zhao Changming was still a little hesitant, the conquering of cancer was so easily handled by this female doctoral student who relied on her superior body?It's just that he can only persuade, not reprimand, because of sympathy.

"Relax! Isn't it just a virus? Let's start the acceptance. Don't worry, the animal experiment report will be handed over to you during the acceptance."

Pan Yan looked a little impatient, took out a few reports and wrote them in a hurry. The headline was the report on animal living experiments. She didn't do it at all. The difference from the cell experiment will not be great.The price of another rhesus monkey is about 1 yuan. Recently, a mobile phone without a headphone plug was released, and the remaining research funds can just buy one.

"The acceptance inspectors are from the general hospital, you can't make any mistakes!" Zhao Changming issued an ultimatum.

When the acceptance work was carried out in an orderly manner, Zhu Cheng naturally got the news that the cancer had been overcome.

Did this woman really do something serious?He looked at the paper with doubts. Relying on the intuition and questioning nature of a scientific researcher, he always felt that there was a big problem with this paper.

He is naturally aware of the M1 virus. If the treatment direction of the winger is to normalize the cancer cells, then the M1 virus is to eliminate it. These two directions are also the current mainstream debate.

In human history, there is only one virus that humans have truly defeated and eliminated, which is called smallpox.And what killed smallpox was the smallpox vaccine discovered by Edward Jenner from cowpox.After many improvements, smallpox was finally eradicated.

How can it be eradicated without immunity?He is more optimistic about the winger's plan. This time it is a once-and-for-all method. For the general-purpose M320 virus of the 1 Biochemical Institute, in Zhu Cheng's view, it is more of an auxiliary method.The cure still depends on winger's research on protease inhibition.

Not only Zhu Cheng was impatient, but the winger was also impatient.Inhibitors of proteases capable of degrading cell viscosity have not been found for a long time.

"Mentor, I have a question. We have a big project called the International Human Proteome Project."

A student walked up to the winger with a gloomy face. When the winger was in a bad mood, there were few people around him. This student was very bold.

"I have something to say!"

The student continued to say timidly: "Then why do we inhibit proteases? Can we solve this problem from another way of thinking? Looking for proteins that can increase the viscosity of cell membranes..."

He stopped in the middle of speaking, because he saw the winger's face became more gloomy, and he thought to himself whether he should continue talking.

"Very good! What's your name?!" The winger nodded and asked.

"Suo Yunfeng." Could it be that he is about to be fired?This is really shooting yourself in the foot, and the gain outweighs the gain.His mood was instantly as gloomy as the winger's face.

"Well, very good, Suo Yunfeng, you will be my experimental assistant in the future." Wing Feng ordered coldly, but the joy on his face could not be concealed.He offers a pretty good suggestion!
Pan Yan is now submitting papers to Nature, and hopes that her papers on the general M1 virus can be published in a special issue of Nature Life Sciences.

During the domestic inspection and acceptance work, Zhao Changming naturally discovered that Pan Yan did not conduct live animal experiments, and forged the report!It's just that the acceptance procedure has already started, just like poured water, if it is forced to stop, it is a major scientific research accident, and this responsibility is likely to stop him from being the deputy director in the future, and there is no possibility of moving forward.

Even after publication, acceptance is complete.The follow-up new drug development process is also a rather long process, just make up for the animal experiments!
This was Zhao Changming's plan, and he ordered Pan Yan to carry it out, but he didn't expect that the scientific research funds had been embezzled by her, and a rhesus monkey that didn't exist was added to the laboratory list. Under the glory, no one has ever mentioned it.

Zhu Cheng called Zhang Youlin and asked for some samples of the universal M1 virus. There are quite a few of these samples, but without Zhang Youlin's relationship, he couldn't get them at all. He always felt that the universal M1 virus was a bit strange. The performance of the virus far exceeds the valuation of the data.

He walked into the biological laboratory with the universal M1 virus sent by Zhang Youlin.

Feng Feng divided the biological laboratory into several major groups, namely the microbiology laboratory, cell biology laboratory, molecular biology laboratory, tissue culture laboratory, and in vivo laboratory.

The experimental animals in the living laboratory are all kept on the third floor and specially supervised. Zhu Cheng put on a chemical protective suit and entered the living laboratory through a long disinfection channel.

Open the scanning tunneling microscope, the two inventors of this microscope won the 1986 Nobel Prize in Physics.Scanning tunneling microscopy is often used to observe the internal structure of NDA at the base pair level, using the tunneling effect in quantum effects to detect the surface structure of substances.

Although people have not yet understood quantum mechanics and quantum effects, it does not prevent people from using these phenomena.He needs to pry open the protective shell of the universal M1 virus and observe the DNA of the virus.

Turn off the ultraviolet disinfection lamp on the ultra-clean workbench, turn on the blower, and open the safety box of the universal M1 virus. Rows of blue injections are used to remove a little sample with a micro-bright pipette.

But this observation yielded nothing.He still can't see the genetic code, just like seeing assembly language as his mother tongue.He shook his head, turned on the communication of Zhiyan, and ordered the breeder on the third floor to bring down a tree shrew.

He wants to do his own experiments to verify the virus.It is different from the experimental animals of 320 Biochemical Institute.The experimental animals he used were tree shrews.

Rhesus monkeys, India is no longer ready to sell!The price has soared, and it takes one to do a virology, immunology, and pathology experiment. The cost has soared from one thousand yuan to ten thousand yuan.

Although mice are genetically similar to humans, they are generally not used for research because their physiological structure is too different from that of humans. With the increasing use of non-human primates represented by monkeys, the domestication and The number in the wild is getting smaller and smaller, making it difficult to buy.

Therefore, tree shrews have come into people's eyes. As an animal that is closest to humans in terms of anatomy and physiology besides primates, it has officially become the new favorite of human biochemical laboratories. Some people analyze different species of tree shrews. A large number of features of the skull, teeth, muscle groups, gastrointestinal tract, nervous system and reproductive system reveal that tree shrews and lemurs have many common features, so tree shrews are classified into the prosimian suborder.

Regardless of the source of the hero, the tree shrew is a non-rodent omnivorous experimental animal with the characteristics of high mobility and extreme sensitivity to social and environmental pressure. Ideal experimental animals for research such as stimulation.

Turn on the constant temperature air bath shaker and start the cultivation of the universal M1 virus. The sample is just a little. As a biology doctoral student, he naturally memorizes the cultivation of the virus by heart.

The experimental tree shrews were gently injected with the general M1 virus.

The tree shrew was carried quietly. This tree shrew is a specially bred cancer tree shrew. Some blood, to see the amount of cancer cells in the blood.

Reduce quickly!As a tree shrew suffering from advanced cancer, the reduction of blood cancer cells in the body naturally means that M1 is a success!

What he verified was lymphoma.

Is it really all right?Zhu Cheng was still a bit skeptical. Although there seemed to be some discrepancies between the current experimental data and the experimental data provided by Pan Yan, this slight discrepancy could not be used as an argument that the general-purpose M1 virus was invalid.

"When did you come here? The big boss did the experiment himself. What happened?" Qi Shuli hadn't received the news of the common M1 virus yet.Of course I don't know what experiment he is doing.

Zhu Cheng told Qi Shuli about Pan Yan's recent breakthrough of cancer.

Even through the thick protective clothing, he could feel the change in Qi Shuli's mood. This feeling of being only one step away from others is really driving people crazy!
They are about to succeed!A new way has been found!But someone got there first!How could Qi Shuli not be troubled by this?She was not for the Nobel Prize, but for the winger. He managed to achieve some results, and it was unknown whether the winger could withstand such a blow.

"Pan Yan's data is obviously abnormal! I don't think she has really completed it, but I can't find any loopholes. All the values ​​​​of the in vivo experiment are in line with her experiment report."

Zhu Cheng is ready to accept the achievement of this woman - overcoming cancer.

"You can keep an eye on this tree shrew. I just injected him with M1. If the experiment is successful, the tree shrew will probably recover." He was about to leave. too much.

People only remember that the father of the atomic bomb was Oppenheimer. Who still remembers the famous German physicist Heisenberg who deliberately miscalculated a decimal point and delayed the process of the German nuclear bomb explosion?
ps: Routinely ask for a recommendation ticket.

Recommend a book, the system sword fairy, the sword fairy is the fairy, I always think so.

(End of this chapter)