Xueba’s medical black technology system

Chapter 158 An unprecedented clinical trial

When Lu Liang got up from the bed, it was already past eight o'clock.

After briefly washing up, Lu Liang turned on his computer and opened a folder on the desktop.

There is an Excel file stored in the folder.

Last night, he sorted out the raw data that Manager Nie sent him and made a simple analysis.

Later, Lu Liang opened his mailbox and sent the file to Ji Hong through the mailbox.

After doing all this, Lu Liang closed his computer and walked towards the school cafeteria.

Just when Lu Liang was standing in line at the window to buy breakfast, he felt someone tap him on the shoulder.

Lu Liang looked back and found Wang Wentao standing behind him, covered in sweat.

"Good morning, Senior Brother Lu."

Wang Wentao greeted Lu Liang with a simple and honest smile.

When Lu Liang saw Wang Wentao, he remembered what happened last night again, which made Lu Liang feel depressed.

But Lu Liang had no choice. After all, it was he who gave Wang Wentao the bad idea.

"Are you going for a morning jog?" Lu Liang asked, looking at Wang Wentao who was covered in sweat.

"Yes, I'll have breakfast after my morning run and then get ready to go to the study room."

Wang Wentao said: "By the way, I met Teacher Ji on the way here just now."

"Teacher Ji is back from a business trip?"

Lu Liang raised his eyebrows. After finishing breakfast, he could go to Ji Hong to talk about the follow-up experiments.

Wang Wentao nodded, then said thoughtfully: "However, I see that Teacher Ji has heavy dark circles under his eyes. He must have rushed back overnight. There must be something urgent."

Lu Liang nodded suddenly.

After breakfast, Lu Liang walked out of the cafeteria. He casually picked up a bottle of instant coffee from the small shop next to the cafeteria, and then walked towards the teaching building.

When he came to the door of Ji Hong's office, Lu Liang saw that the door of the office was open.

Lu Liang stood in the corridor and looked into the office. He saw Ji Hong with two big dark circles under his eyes, a thermos cup in his hand, drinking hot water, his eyes fixed on the screen, as if he was thinking about something.

Lu Liang knocked on the office door, and Ji Hong looked up at the door.

After seeing Lu Liang, Ji Hong nodded and said with a smile: "Xiao Lu, you came quite quickly."

Lu Liang put the bottle of coffee he bought on the table and said, "I heard from Wen Tao that teacher, you came back overnight, so I brought you a bottle of coffee to refresh yourself."

Ji Hong glanced at the coffee on the table, then smiled and shook his head: "Forget it, I don't drink coffee, I'm not used to drinking that stuff."

Lu Liang was a little surprised: "Teacher, what did you drink when you were studying abroad?"

"Hot water."

Ji Hong shook the thermos cup in his hand.

"Uh" This is what Lu Liang didn't expect.

"Okay, Xiao Lu, stop talking nonsense and let's talk about the business first." Ji Hong brought the topic back on track.

He came back all night not just to say that he had these things.

Ji Hong glanced at the data Lu Liang sent him on the screen and said, "I have already read the test data you sent."

When he said this, Ji Hong paused, and he spoke again: "Judging from the current results, the method of inhibiting the PD-1+TIGIT immune checkpoint is indeed feasible." Lu Liang asked: "So, teacher, this We should be able to prepare for clinical trials, right?”

Ji Hong nodded: "However, I think the subjects of clinical trials may need to make some adjustments."

"How to adjust?" Lu Liang was a little confused. Aren't PD-1/TIGIT inhibitors drugs for treating lung cancer? They must be targeted at lung cancer patients. Is there anything that can be adjusted?

Ji Hong explained Lu Liang's doubts: "My positioning of Xiao Lu's drug is a second-line treatment drug."

Cancer cells, just like bacteria, can also develop resistance to drugs, so drugs are administered in the same way.

Generally speaking, for the treatment of lung cancer patients, first-line drugs are used first.

When cancer cells become resistant to first-line anticancer drugs, higher-level second-line drugs will be used for treatment.

Ji Hong continued: "Furthermore, Xiaolu, your drug has been designed to cover all types of genetic mutations since the beginning of research and development."

"Therefore, this time's clinical samples include not only lung cancer patients with various gene mutations, but also lung cancer patients who have developed drug resistance."

“In some ways, this is an unheard-of clinical trial for a lung cancer drug!”

When Ji Hong said this, his heartbeat couldn't help but speed up, and he licked his slightly dry lips.

You know, other drugs basically target individual types of genetic mutations and target a certain group of lung cancer patients.

Even sugemalimab can only cure several types of mutations such as EGFR and AKL at the same time.

"That's a huge challenge for your drug."

"But if we can succeed, lung cancer will no longer be scary, it will even become a chronic disease that can be cured!"

Ji Hong's voice was trembling, and his eyes became particularly hot.

He has spent most of his life on the research path of lung cancer treatment. He is like a pioneer holding a torch and constantly groping forward on the dark road.

And now he finally sees the end of this road, the end he has been chasing so hard. How could he not be excited?

Lu Liang thought for a moment and replied: "Then I'm quite confident."

After hearing what Lu Liang said, Ji Hong couldn't help but smile: "In that case, let's go, I've already contacted a good person."

Lu Liang was stunned for a moment: "Teacher, where are we going?"

"cancer Hospital."

Cancer Hospital, Ward 702.

"Doctor, is there really no other way?" The woman looked at the director of the department pleadingly, tears welling up in her eyes.

The director looked in front of him and sighed heavily. In the past month or so, they had tried every means.

The experts invited changed one after another, but after learning about the condition of the woman's husband, they all shook their heads.

The director said: "Sorry, we have tried our best."

The woman plopped down and knelt down in front of the director, which shocked the director. He quickly reached out to help her: "What are you doing?"

But the woman's voice was hoarse and she grabbed the director and refused to get up: "Doctor, I beg you, please do a good job and help us again. My two children are still young, and I don't even dare to tell them about this!"

Then, the woman seemed to remember something: "Doctor, don't you have some other experiments? Try that one, please, even if it's just a try."

The director does not know about clinical trials, but at present, there are no clinical trials for second-line drugs. If there were, they would have tried them long ago.

Just when the director was about to speak, there was a sudden knock on the door in the ward.

A doctor opened the door and walked in. He walked quickly to the director's side, and then whispered a few words in the director's ear. The director's expression suddenly changed!
(End of this chapter)