Xueba’s medical black technology system

Chapter 148 Super Large Experiment

After coming out of the library, Lu Liang did not go back to the dormitory directly, but went outside the school to pick up the express delivery.

Just now, the courier point sent me a text message to inform me that the courier has arrived at the site.

Lu Liang hadn't purchased anything online recently, so as expected, this express delivery was a monoclonal antibody drug sample sent by Tian Li.

It is already summer, and the weather is gradually getting hotter. Although Tian Li may put ice packs to cool down, Lu Liang does not dare to let the drug samples stay at the express station for too long.

Lu Liang crossed the street and arrived at a community next to the school.

Several nearby express delivery stations are in this community, but when he saw the long queue at the door of the express delivery station, Lu Liang couldn't help but grin.

The queue to receive express delivery was winding and winding like a long queue, which made Lu Liang have to admire the consumption power of contemporary college students.

But no matter how long the line is, you still have to wait.

Lu Liang stood at the back of the team and slowly followed the team forward.

The comments from the students in front were heard.

"What did you buy on June 6.8th?"

"I bought an electric toothbrush. It only costs more than 30 yuan. Isn't it awesome?"

"Then what do you think? I bought a whole box of tissue paper for only 9.9!"

"Hold the grass, awesome!"

Amidst the loud noises around him, the student gradually lost himself.

Lu Liang, who was in the back, looked slightly weird as he listened to these discussions.

Finally, after waiting in line for more than 20 minutes, it was Lu Liang's turn. After reporting the pickup code, the service staff at the express delivery point brought over a large box.

This made Lu Liang once again certain that this thing was the drug sample sent by Tian Li.

Lu Liang picked up the box, and the heavy weight came from his hands.

This is at least 40 kilograms, right?

How many ice bags must be stuffed into the foam box to make it so heavy?

In desperation, Lu Liang could only pick up a shared electric donkey on the side of the street. After putting the foam box on the small electric donkey, Lu Liang rode on the small electric donkey and drove quickly towards the teaching building.

After finding a parking spot under the teaching building and parking the e-mule, Lu Liang picked up the foam box and was about to go upstairs when he met Wang Wentao coming down from the stairs.

"What a coincidence, senior brother, what are you holding?" Wang Wentao asked curiously.

"Drug samples." Lu Liang replied.

After hearing what Lu Liang said, Wang Wentao's eyes suddenly lit up: "Brother, are we going to start an experiment soon?"

Lu Liang thought for a moment and then nodded: "It's time to get ready. Just prepare yourself. When the time comes, you'll probably be so busy that you get dizzy."

But Wang Wentao had no intention of retreating. On the contrary, his eyes were filled with fighting spirit: "Don't worry, senior brother, I've been waiting for this day for a long time."

As he said that, Wang Wentao looked at the box in Lu Liang's hand, and he reached out to pick it up: "Brother, let me help you get the things."

Lu Liang was a little worried: "Be careful, it's very heavy."

"Hey, senior brother, I come from the countryside. I don't have any special skills. I'm just strong. And it's just some drug samples. How heavy can it be? Senior brother, let go. I'm holding the grass!"

Wang Wentao was full of confidence just now, but when Lu Liang pulled out his hand and the weight of the foam box fell entirely on Wang Wentao's hand, Wang Wentao's expression suddenly changed.

If Lu Liang hadn't pulled Wang Wentao, Wang Wentao would have almost rolled down the stairs holding the box.

After standing firm, Wang Wentao looked at the box in his hand with a somewhat horrified look: "Brother, is it really only drug samples that are contained in this?"

"And a little ice pack." Lu Liang coughed dryly.

"A little bit?" Wang Wentao's tone has begun to doubt life: "This is at least as heavy as a bag of pig feed!"

"Okay, you take the box to the laboratory, then take out the medicines inside and put them in the refrigerator. I'll go up and sort out the test plan."

Lu Liang told Wang Wentao how to deal with it. Then he remembered something, looked at Wang Wentao and asked, "Is your computer here?"

"On my desk."

"Lend it to me." Lu Liang asked Wang Wentao for his opinion. His computer was placed in the library, but he didn't bring it over because he thought it would be troublesome.

It seems that I have to buy myself another computer and put it in the study room, otherwise it will be troublesome to carry the computer back and forth all day long, Lu Liangliang thought.

After obtaining Wang Wentao's consent, Lu Liang walked towards Wang Wentao's study room.

He came to Wang Wentao's desk. On the desk was an ASUS Crash Fortress. After Lu Liang turned on the computer, he noticed a folder on the desktop in the upper left corner - the Minotaur series.

Lu Liang's expression became strange. He didn't realize it. It turned out that Wang Wentao liked this.

However, this is other people's privacy after all, and Lu Liang is too embarrassed to delve into it.

Lu Liang focused his attention on business. He created a new word document and began to organize the entire experiment process.

The first is the consumables used in the experiment.

When he brought Wang Wentao into the laboratory before, he had already prepared the required consumables, but Lu Liang still listed them on the document to avoid any omissions.

Site, cycle, operating steps, sampling time, sample processing
Lu Liang simulated the entire process in his mind and recorded each step in detail to avoid problems during the experiment.

Most of the process has been determined, and all that remains is the test subjects.

Needless to say, the test subjects were naturally mice.

However, the selection of mouse strains is also very particular. Some common mouse strains include C57BL/6N, CH3, DBA/1, etc.
But cancer model mice are different. Currently, the most widely used animal model of lung cancer in the world is the Kras-LSL-G12D mouse model.

This is a mouse model in which Kras mutants are activated by crossing with Cre transgenic mice specific for lung epithelial cells, leading to the development of lung cancer.

I don’t know if any of those biological companies have it, Lu Liangliang thought, but in any case, the mouse strain was first designated as Kras-LSL-G12D mouse.

Finally, there is the number of mice.

According to international standards, if the test subjects are mice, at least 12 mice are needed in each group to prove that your test is universal.

Only when such research is published will journals accept it.

Lu Liang's plan is to set up separate trials based on the types of lung cancer gene mutations.

For example, one test is conducted for EGFR mutations, and one test is conducted for ALK mutations.
Then seven groups were established for each experiment, namely:

Blank control group.

Low, medium and high dose drug control groups.

Low, medium and high dose test groups.

So there are seven groups in one experiment.

Then add in the number of experiments that need to be carried out
Lu Liang clicked quickly on the calculator, calculating the number of mice needed for this experiment.

However, when he saw the final result, even he was stunned.

You know, when others do experiments, 30 or 40 mice are basically enough.

A batch of experiments involving more than 100 mice is considered a large experiment.

The number of mice needed for his experiment was - 1764!

what is this?
A very large experiment?

(End of this chapter)