Xueba’s medical black technology system

Chapter 136 The horror of lung cancer

At this moment, Ji Hong's voice sounded behind Lu Liang: "Xiao Lu, let's go."

Lu Liang looked back and found that Ji Hong had ended the conversation with the director. Lu Liang nodded and followed Ji Hong's footsteps.

"Goodbye brother."

Before Lu Liang left, the little girl waved to Lu Liang.

Lu Liang waved and then walked into the elevator of the inpatient department with Ji Hong.

After coming out of the inpatient department, the two came to the parking lot. After getting in the car, Lu Liang asked: "Teacher, how are you doing?"

Ji Hong sat in the driver's seat. He did not start the car, but rolled down the window and sighed: "I couldn't help much."

In fact, seeing Ji Hong's appearance, Lu Liangliang probably guessed the final result even if Ji Hong didn't say anything.

Finally, after a long silence, Ji Hong spoke: "Xiao Lu, do you know where the real horror of lung cancer is?"

"Is it because the drugs are expensive?" Lu Liang asked.

Ji Hong shook his head: "It's not a problem with the drugs. On the contrary, among those targeted drugs for treating cancer, drugs for treating lung cancer are already relatively cheap."

"Furthermore, due to medical insurance, most families can still afford lung cancer treatment drugs."

To give the simplest example, the ex-factory price of osimertinib, a third-generation targeted drug targeting EGFR gene mutations, is 15300 yuan per box.

However, after entering the country, after negotiation with medical insurance, the price was close to 5500 per box.

After being reimbursed by medical insurance, basically ordinary families can buy medicines for only about 1500.

For ordinary families, this is still affordable.

"What's the problem?" Lu Liang asked with some confusion.

Ji Hong said: "The really scary thing about lung cancer is its low survival rate. Once 80% of lung cancer patients are diagnosed, they are basically in the late stage of lung cancer."

"Because lung cancer basically doesn't show any symptoms in the early stages. Wait until you feel uncomfortable before going for a check-up. It's basically late stage lung cancer."

"Moreover, the survival rate of lung cancer is extremely low. Even with drug treatment, only a handful of people can survive more than five years."

When he said this, Ji Hong paused, and then said: "Xiao Lu, have you read the white paper report on the quality of life of lung cancer patients?"

A white paper is a formal document issued by the government.

Lu Liang shook his head. He had not read any documents in this regard.

Ji Hong said: "According to the statistics in the white paper, there were 87 new cases of lung cancer and 71 deaths in China last year!"

When he heard this number, Lu Liang's pupils couldn't help but shrink.

There are 81 new cases. This number does not seem to be many, but if one death is added, 71 are added.

It is enough to see how terrible the mortality rate of lung cancer is.

Ji Hong continued: "This is lung cancer. Even on a global scale, lung cancer has always ranked first in the proportion of cancer deaths."

Lu Liang couldn't help but ask: "Is there not enough medicine?"

Ji Hong smiled bitterly and shook his head: "No, the real reason is that lung cancer is more complicated than you imagined. Xiao Lu, you should know about genetic mutations."

Lu Liang nodded, this is common sense that everyone knows.

Gene mutations are the root cause of cancer.

Normal cells directly turn into cancer cells that proliferate and divide wildly after genetic mutations occur.

Ji Hong continued: "Different genetic mutations often mean that different drugs are needed to treat them."

"A drug that treats lung cancer may work in one lung cancer patient, but not in another lung cancer patient because of different genetic mutations in the lung cancer cells in their bodies."

What Ji Hong said next is truly shocking: "According to current statistics, there are more than 20 different genetic mutations in lung cancer!"

"More than 20 kinds?!" Lu Liang looked horrified.

What do more than 20 genetic mutations mean?
Give the simplest example.

Lu Liang once analyzed a drug used to treat cancer, which is a second-generation tyrosinase inhibitor used to treat chronic myelogenous leukemia.

There is only one cause of chronic myelogenous leukemia, and that is a mutation in the Bcr-Abl fusion gene.

In other words, chronic myelogenous leukemia is a disease caused by a genetic mutation.

As long as there is a drug that can solve the problem of Bcr-Abl gene mutation, all patients with chronic myelogenous leukemia can be treated.

But lung cancer?

There are more than 20 genetic mutations.

Every genetic mutation can cause lung cancer.

Each mutation requires a new targeted drug to treat.

In other words, more than 20 different targeted drugs are needed to fully cover the treatment of all lung cancer patients!

Lu Liang suddenly understood why the treatment of lung cancer was so difficult.

Ji Hong started the car and drove slowly towards the school.

Along the way, the atmosphere in the car seemed particularly depressing.

After parking at the school gate, Lu Liang got out of the car and said to Ji Hong in the car: "Teacher Ji, I'm going back to the dormitory first."

Ji Hong nodded: "I've been running all day today, so go back and rest early."

After greeting him, Lu Liang walked towards the school dormitory. On the way back to the dormitory, Lu Liang's mind still echoed what Ji Hong said to him at that time.

More than 20 genetic mutations.

Lu Liang couldn't help but sigh.

After returning to the dormitory, Lu Liang sat down on the chair.

When Cheng Ming and others saw Lu Liang coming back, they immediately said hello: "Old Lu, you are back. Where have you been?"

"Go out for a walk."

Lu Liang didn't want to explain too much, so he said casually. Then he glanced at Cheng Ming and the others: "Where are you going?"

"Let's go to the football match, will we come together?" Liu Qi asked excitedly.

"What ball game?"

"What other ball games, basketball games, school games can there be?" Cheng Ming said.

"Not interested in."

Lu Liang lay on the chair and said with a lack of interest. He was thinking about lung cancer right now, so how could he still have the time to watch a football match?

"Then let's go first." Cheng Ming and a group of people hurriedly walked out.

Lu Liang seemed to have remembered something again. He suddenly looked at Cheng Ming suspiciously: "Don't you understand basketball? Why are you following along to join in the fun?"

In Lu Liang’s impression, Cheng Ming had almost never touched basketball. He didn’t even understand the rules of basketball.
"I'm watching the ball, not the game."

Cheng Ming hurriedly said these words, and then left with Liu Qi.

Lu Haoliang was left in a daze for a while before he came back to his senses.

After Cheng Ming and others left, Lu Liang also sat up straight and started to turn on the computer to inquire about lung cancer.

(End of this chapter)