Xueba’s medical black technology system

Chapter 108: Domestic antibiotics not good?
The results of the bacterial sampling and culture came out the next day.

After seeing the results of the bacterial microscopy, Zhu Kang's face suddenly became ugly.

Facts have proved that sometimes, we are just afraid of what will come.

Judging from the microscopic examination, the two elderly people had septicemia caused by Enterococcus faecalis infection.

Due to the abuse of antibiotics in the past, Enterococcus faecalis has already developed drug resistance.

Unlike other bacteria, Enterococcus faecalis has evolved resistance to vancomycin.

This means that even if vancomycin is used now, it is useless.

The only drug that works now is linezolid.

That is, the first generation oxazolidinone antibiotics.

To be honest, Zhu Kang was also scared when he took this drug.

Because linezolid is the last resort against infection, if this drug fails to work, there is really no drug available.

Therefore, Zhu Kang really didn't want to use this last line of insurance until he had to.

But now that the situation is urgent, Zhu Kang can no longer take care of so much.

After getting approval and consent from the director of the infectious disease department, Zhu Kang got the drug linezolid.

Then Zhu Kang rushed to the ICU non-stop again.

After completing the infusion of linezolid through intravenous injection, the breathing of the two elderly people began to become stable.

Watching the vital signs of the two old people return to normal levels.

Zhu Kang couldn't help but let go of the hanging stone in his heart.

Zhu Kang looked at Ms. Wu and Ms. Wang and said, "The patient's condition has stabilized now. If nothing happens, he will be able to fully recover soon."

After hearing Zhu Kang's words, Ms. Wang's face became less worried at this moment: "Thank you, Doctor Zhu.",

"You're welcome, this is what it should be." Zhu Kang said after waving his hand.

However, at this moment, a discordant voice sounded again: "Since this antibiotic is so useful, wouldn't it be enough to use this antibiotic as soon as possible? It has to be delayed until my dad is admitted to the ICU."

Instead of showing any gratitude on her face, Ms. Wu began to complain: "I think your hospital just wants to make more money and deliberately made the disease so serious."

After hearing what Ms. Wu said, Zhu Kang suddenly laughed angrily. If this woman hadn't used antibiotics indiscriminately, the matter would never have gotten so serious.

But now Ms. Wu is accusing him.

Zhu Kangcai was too lazy to argue with Ms. Wu. He let Ms. Wu's chattering voice come from behind and walked into the office to handle his own affairs.

In the next few days, the conditions of the two elderly people improved little by little.

This also made Zhu Kang slightly relieved. If nothing unexpected happens next, the old man can almost be transferred from the ICU to a general ward.

Just when Zhu Kang was thinking about these things.

A nurse hurried into the office: "It's bad, Doctor Zhu, the condition of those two patients has worsened again!"

The sudden news made Zhu Kang's heart suddenly freeze.

What he feared the most had happened.

Linezolid didn’t work!
In other words, bacteria have once again become resistant!
Zhu Kang's face suddenly darkened. He didn't dare to show any slightness. He quickly stood up and rushed toward the ICU anxiously.

When Zhu Kang arrived at the door of the ICU ward, there was already a huge noise in front of the ward.

After seeing Zhu Kang, Ms. Wu immediately shouted: "Can you cure it? If you can't cure it, just tell me earlier. Don't waste my dad's time here."

Zhu Kang suppressed his anger and said, "If you hadn't used antibiotics indiscriminately, this matter would not have been so serious."

Upon hearing Zhu Kang's words, the woman suddenly raised her eyebrows: "It's my fault for saying so. If I can solve it, why would I come to your hospital?"

"Hurry up, is there anything you can do? If there is no other way, I will transfer him to another hospital. You can't cure it, but those foreign-funded hospitals can. Their medical level is much higher than yours."

After listening to Ms. Wu's words, Zhu Kang couldn't help but want to call him a fool.

Now that linezolid has no effect, even if a miracle doctor comes, he can only stare at him, let alone a foreign-funded hospital.

At this time, the nurse came over and said to Zhu Kang: "Dr. Zhu, the director called you to a meeting to discuss the plan."

Zhu Kang knew the seriousness of the matter. Now was not the time to talk nonsense with Ms. Wu. He turned to look at the family member of another patient, Ms. Wang.

At this moment, Ms. Wang's face was full of anxiety and worry: "Doctor Zhu, is my dad okay?"

Zhu Kang took a deep breath and tried his best to comfort Ms. Wang: "Don't worry, we will come up with a treatment plan as soon as possible and do our best to treat her."

After speaking, Zhu Kang did not waste any time and walked towards the conference room.

In the conference room, everyone looked serious. The expiration of linezolid, the last line of insurance for infection, meant that things were getting out of control.

The director said: "Everyone is aware of the current situation. Can you please call everyone over and see if there is a solution that can be come up with?"

As the director finished speaking, the conference room fell into dead silence.

Now even linezolid is no longer useful. Even if a god comes, he can only stare blankly at this situation.

"Would you like to try a sulfa drug?"

Finally, the dead silence in the conference room was broken, and someone tried to suggest: "There have been clinical trials and some drug-resistant bacteria have mutated and become sensitive to sulfa drugs, but the specific mechanism is not yet clear."

"No, this kind of thing is too risky. Who knows if there will be any adverse reactions."

"What should I do? Are there any other medicines I can use now?"

Looking at the noisy conference room, Zhu Kang felt a little overwhelmed for a moment. The incurable situation was so difficult and troublesome.

Just when everyone felt that there was nothing they could do, an intern sitting at the end weakly raised his hand.

This scene surprised the director: "Doctor Gu, what can you do now? Tell me."

The intern named Gu stood up at this time.

"That's it, director. I have a classmate who works in the hospital next door. I heard from him that their hospital recently had a new antibiotic undergoing clinical trials. I wonder if I can try it."

But before he finished speaking, he was interrupted by another doctor: "I guess it's not very useful. Now that linezolid is no longer used, what's the use of ordinary antibiotics?"

Other doctors nodded in agreement: "Unless that antibiotic has a completely new mechanism of action, it will not have an impact on this kind of drug-resistant bacteria at all."

Just when Zhu Kang couldn't help but want to give up, the voice of doctor surnamed Gu sounded again.

"But... I heard that it is a new generation of oxazolidinone antibiotics!"

As soon as these words came out, there was a sudden silence in the entire conference room. Everyone looked at the intern doctor surnamed Gu in shock. Zhu Kang subconsciously held his breath.

At this moment, there is only one thought in everyone's mind.

If it is a new generation of oxazolidinone antibiotics.
The first person to react was the director.

"Are you sure the news is true?"

"determine."

"Then you should contact the hospital over there quickly."

After the director finished speaking, he then looked at Zhu Kang next to him: "Dr. Zhu, go and communicate with the patient's family to see if they are willing to accept the drug in clinical trials. Now there is only one drug that has a chance."

The entire meeting took less than half an hour. As the new treatment plan was finalized and things were arranged one by one, the entire infectious disease department became busy.

After coming out of the conference room, Zhu Kang rushed towards the ICU again.

He needed to inform the plan as soon as possible and seek the consent of those two people.

When they rushed back to the entrance of the ICU ward, Ms. Wang and Ms. Wu were still waiting.

After seeing Zhu Kang come back, Ms. Wu couldn't help but ask: "What's going on? Is there anything your hospital can do?"

Zhu Kang's eyes skipped directly from the woman surnamed Wu. He selectively ignored this woman, but looked at Ms. Wang.

"That's right, Ms. Wang, let's have a meeting to discuss it. There is another drug that can treat patients, but that drug is still in clinical trials and will have certain risks."

"If you agree, we can use that experimental drug for treatment."

Zhu Kang explained his treatment plan to Ms. Wang in detail.

After listening to Zhu Kang's treatment plan, Ms. Wang's face showed hesitation and hesitation, because Zhu Kang made the risks very clear.

This is still a clinical drug. How effective it will be after use and whether it will cause any side effects are all unknown.

But before Ms. Wang could answer, Ms. Wu’s sharp voice rang out first.

"What, clinical trial drugs, are you planning to use my dad as a guinea pig!" Ms. Wu said in a loud voice.

After hearing what Ms. Wu said, Zhu Kang explained: "Ms. Wu, although this drug is still in the clinical trial stage, everything is in compliance with the procedures, and I am asking for your consent now. If you don't agree, we will not use the drug. .”

This slightly softened Ms. Wu's expression: "Then the drug you are talking about, is it imported or domestically produced?"

Zhu Kang replied: "As far as we know, this antibiotic is domestically produced."

"It's still domestically produced. I don't agree. I absolutely disagree. There is no guarantee at all for domestically produced drugs. Who will be responsible if something goes wrong!"

Ms. Wu's voice suddenly rose a little higher, attracting other people in the corridor to look at her.

Zhu Kang took a deep breath and explained patiently: "As far as we know, this drug was developed by Lu Liang, a student of Professor Ji from the Pharmaceutical University. He developed domestic drugs for treating diabetes and leukemia. In terms of drug research and development, they The technology is no less than that of foreign pharmaceutical companies.”

However, Ms. Wu did not listen at all: "I don't care who developed this drug. I only know that imported drugs cannot cure diseases, and it is even more impossible to expect domestic drugs."

"I absolutely disagree with this matter. I want to transfer to the hospital now."

Zhu Kang still wanted to persuade him patiently: "Even if you are transferred to one of those foreign-funded hospitals, there is nothing they can do without medicine."

Ms. Wu sneered: "That's because you are not good enough. Foreign-funded hospitals must have more advanced drugs. If you can't cure it, it doesn't mean that others can't cure it either."

Zhu Kang had already said this when he met Ms. Wu, and Zhu Kang didn't bother to refute it.

This reminded Zhu Kang of a sentence.Let go of the need to help others and respect the fate of others.

Zhu Kang said calmly: "Our hospital will not prevent you from transferring to another hospital. You can go through the transfer procedures now."

After saying this to Ms. Wu, Zhu Kang looked at Ms. Wang: "Ms. Wang, do you think this treatment plan and the risks are acceptable?"

Ms. Wang was still a little worried and asked: "Dr. Zhu, is that medicine really reliable?"

Zhu Kang thought for a moment and then replied: "I think the chance is great."

Zhu Kang had heard more or less about Lu Liang's stories on the Internet. It was those exaggerated deeds that made Zhu Kang somewhat certain and confident about this new antibiotic.

After listening to Zhu Kang's answer, Ms. Wang took a deep breath. She knew nothing about medicine, and she knew that the only thing she could do now was to listen to the doctor.

Ms. Wang nodded: "Okay, then I agree."

With that said, Ms. Wang signed her name on the risk book.

Ms. Wu on the side couldn't help but sneer after seeing this: "How dare you. Experimental drugs are very risky. Considering that your dad and my dad are neighbors, don't blame me for not warning you. "

Ms. Wang ignored Ms. Wu's words, but looked at Zhu Kang and asked, "Dr. Zhu, when can the treatment begin?"

Zhu Kang replied: "Don't worry, I will make arrangements as soon as possible."

Seeing that neither of them paid attention to her, Ms. Wu snorted coldly and turned around to go through the transfer procedures.

Soon, an ambulance drove into the hospital, picked up Ms. Wu's father from the ICU ward, and sent him to a foreign-funded hospital in the city.

That night, the person in charge of the clinical trial from the next city rushed over. After learning the patient's detailed information from Zhu Kang and confirming the patient's infection status, he started drug treatment.

Before the treatment, Zhu Kang couldn't help but feel nervous. Although he believed in Lu Liang, this was a drug that was still in the clinical trial stage after all.

It is not clear at all what the specific effect will be.

Fortunately, the person in charge of the clinical trial comforted him: "Don't worry, we have had more complicated and serious clinical cases than this before, but they were all successful in the end."

"Is it really that good?" Zhu Kang asked in disbelief.

The person in charge of the trial nodded: "This drug is a broad-spectrum antibacterial drug, and its antibacterial mechanism is completely new. In other words, no bacteria have yet become resistant to this drug."

This made Zhu Kang couldn't help but click his tongue.

On the first day after taking the medicine, Zhu Kang saw the effect of the medicine. The patient's physical signs gradually stabilized and began to return to normal levels.

The effect of this medicine was better than Zhu Kang imagined, but this did not make Zhu Kang relax his vigilance.

This was also the case when linezolid was used before.

In the first two days after taking the drug, the drug had a slight effect and allowed the patient to recover a little. But when the linezolid expired, the situation took a turn for the worse.

Zhu Kang could only constantly monitor the vital signs displayed on the instrument.

second day, third day
Normal blood pressure, normal heart rate, normal white blood cell count, and normal blood oxygen saturation
After looking at the patient's blood test data, Zhu Kang's tense face finally showed a smile. This time, there was finally no accident.

Judging from the old man's recovery, it is now possible to transfer the old man from the ICU to a general ward for observation. He can even be discharged from the hospital after confirming that there is no problem in a few days.

However, some people are happy and some are sad.

When everything goes well on Zhu Kang's side.

Harmony Hospital.

Ms. Wu followed a doctor anxiously: "Doctor, why hasn't my dad's condition improved at all? What's going on?"

When she was in the city hospital before, Ms. Wu still felt that the foreign-funded hospital was taking care of everything, so she didn't feel anxious when she saw that her father's condition had not improved.

But now, she has been transferred to the best foreign-funded hospital in the city, but she still hasn't seen her father's disease improve.

At this moment, Ms. Wu finally panicked.

The doctor walking in front stopped at this moment. He turned back and said: "I'm sorry, Ms. Wu, your father's drug resistance is very serious at present. We have no medicines available at the moment."

"Impossible, aren't you a foreign-funded hospital? Shouldn't you have more advanced imported medicines?"

Ms. Wu asked subconsciously.

The doctor sighed: "We have already used all the available drugs, including linezolid. In this case, there is nothing we can do!"

Ms. Wu's face suddenly turned pale.

Seeing this, the doctor comforted him: "But don't worry, Ms. Wu, we have sought help from other hospitals, and then we found out that there is currently an antibiotic in the clinical trial stage, and it has achieved a lot of clinical success."

When Ms. Wu heard this sentence, her eyes suddenly lit up: "Is it a new drug from abroad?"

"No, it's just an antibiotic drug developed in your country." The doctor shook his head and replied.

"And there is a clinical trial of a drug in the city hospital. The symptoms are exactly the same as your father's. The condition improved after taking the drug. If you need it, we can arrange to transfer you to the hospital as soon as possible."

Domestic antibiotic drugs?

When she heard the doctor's words, Ms. Wu's head was suddenly hit by a sledgehammer and began to buzz.

She realized in an instant that the domestically produced antibiotic drug that the doctor said was quite effective was the same antibiotic that Zhu Kang had asked her about before she was transferred to the hospital.

However, her choice at that time was to refuse without hesitation and to belittle him.

Now listen to what this means, the effect of the drug is pretty good now.

Ms. Wu's intestines were turning green now, and her face turned red and white.

You know, when she was transferred to the hospital before, her attitude was very arrogant. Now that she is transferred back to the hospital, doesn't she look like a deadbeat?

But when she thought of her dying father lying in the ICU, Ms. Wu could only nod in agreement.

After all, she didn't know how long her father could last.

After seeing Ms. Wu's agreement, the doctor nodded: "Don't worry, we have contacted the hospital over there, and medical staff will send you there in a while."

When he said this, the doctor paused and said, "In addition, Ms. Wu, please settle the medical expenses here in cash."

"Oh, alright."

Ms. Wu said as she took the bill from the doctor's hand.

However, when she saw a string of zeros at the back of the bill, Ms. Wu's eyes nearly popped out of her head, and she spoke in shock.

"No, doctor, are you mistaken? 15, only a few days?"

Ms. Wu asked in astonishment: "A bottle of normal saline costs more than 200 yuan, but the hospital outside only costs a few dozen!"

The doctor couldn't help but frowned: "We are a foreign-funded hospital, and the charges are different from those of public hospitals outside. Don't you know, Ms. Wu?"

"But haven't you cured my dad's disease?"

The doctor said calmly: "We have tried our best."

Ms. Wu suddenly looked aggrieved. She had only heard that these foreign-funded hospitals were expensive, but she never thought they were so expensive!

But now, Ms. Wu can only break her teeth and swallow them. After all, she was transferred to the hospital herself.

Zhu Kang looked at the test results in his hands and breathed a sigh of relief.

Judging from the current situation, all physical indicators of Ms. Wang's father have returned to normal, and he is now very energetic.

After a few days of observation in the general ward, the patient can be discharged after confirming that there is no problem.

It's all down to a new antibiotic.

Thinking of this, Zhu Kang couldn't help but clicked his tongue.

He couldn't figure out how this antibiotic was developed. Not only was it powerful and effective against bacteria, but most importantly, it was a broad-spectrum antibiotic.

This is almost equivalent to another barrier after vancomycin.

But precisely because of this, Zhu Kang is certain that once this antibiotic comes out, it will become the last trump card in various hospitals to deal with bacterial infections.

It is precisely because of this that its use is strictly restricted by major hospitals.

It is absolutely impossible for major hospitals to use it except as a last resort.

After all, this is the last line of insurance after replacing linezolid.

Zhu Kang sorted out the test results in his hand and walked out of the office. He was now going to the ward to check on the patient's condition.

However, as soon as he walked out of the office, Zhu Kang saw a familiar figure.

When he saw this figure, Zhu Kang simply chose to ignore it, turned around and left.

Ms. Wu's smile suddenly froze on her face, but she still chased after her bravely: "Doctor Zhu, Dr. Zhu, calm down, it was my problem before, I had a bad attitude, I admit my mistake. "

"Don't dare, don't dare. I'm just a little quack. If you don't complain to me, I'll be thankful." Zhu Kang curled his lips.

Ms. Wu pursed her lips, and the smile on her lips was a little bitter, but she could only continue to plead: "Dr. Zhu, I'm really sorry. I was wrong. Please save my dad."

Zhu Kang said without looking back: "Foreign-funded hospitals can save her, so why come to us? Our medical level is not as high as that of foreign-funded hospitals."

Ms. Wu suddenly blushed. These words were all said by her before, but now they came from Zhu Kang's mouth, and the sarcasm was not too obvious.

But Ms. Wu could only force a smile on her face: "But they don't have any medicine, and I heard that the domestic medicine is really effective."

"It's just so-so. It's not as effective as the imported medicines from abroad. I suggest you use those imported medicines." Zhu Kang's answer was still neither salty nor bland.

Ms. Wu was so anxious that she was about to burst into tears: "Doctor Zhu, please do well. My dad is really dying. He has been transferred to another hospital and is lying in the ICU."

Zhu Kang stopped just now. He turned back and glanced at Ms. Wu: "Have you registered?"

Ms. Wu seemed to realize something. She quickly bowed and nodded: "Thank you Dr. Zhu, thank you Dr. Zhu. I'm going to hang up right now. Now."

With that said, Ms. Wu did not dare to show any slightness and hurriedly ran to register.

(End of this chapter)