Xueba’s medical black technology system

Chapter 101 Drug export, what about the price, hehe
When I returned to school, it was already five o'clock in the afternoon.

Because he didn't have lunch at noon, Lu Liang's stomach began to growl, and he felt endless hunger.

Lu Liang reached out and touched his pocket. He had the student card on him. Lu Liang went straight to the cafeteria without thinking.

After ordering a meal, Lu Liang chose an empty seat and sat down.

But before Lu Liang could grab a few mouthfuls of food, a boy suddenly came over and sat down opposite Lu Liang.

Lu Liang looked up at the other person and found that it was an unfamiliar face, which made Lu Liang feel a little puzzled.

There are not many students in the cafeteria now, and there are so many empty seats around, why does the other party have to sit across from me?
Moreover, he didn't see the other party carrying a plate, so he didn't look like a student coming to eat.

As if aware of Lu Liang's doubts, the boy forced a kind smile on his face: "Classmate, I see that you are relatively weak. Have you ever thought about exercising yourself?"

God is fucking useless, your talents are vain, and your whole family is vain!

Lu Liang rolled his eyes. He didn't know how the other party could tell that he was weak from his 1.8-meter height.

If Lu Liang hadn't considered that it was offensive to expose her breasts in front of a large audience, Lu Liang would have had a frank interview with the person and let him take a good look at what it means to have a natural eight-pack abs.

"So, what do you want to say?" Lu Liang asked calmly, while not forgetting to take a few mouthfuls of rice.

The boy took out a flyer from his back and said with a smile: "Our Figo Gym has recently opened, and we are currently running a special promotion. You can apply for a card at a [-]% discount. Classmates, are you interested in finding out?"

Ha, it turns out that I came here to sell fitness cards.

However, these people no longer sell on the street. Do they go to the canteen to sell?

Lu Liang replied lazily: "I'm not interested in fitness for the time being."

Lu Liang originally thought that his answer was enough to send the other party away, but the fact was beyond Lu Liang's expectation.

After seeing that Lu Liang was not interested in fitness, the man "swiped" and took out a few small leaflets from nowhere.

"It doesn't matter if you're not interested in fitness. I have several hip-hop and guitar studios here that are recruiting students. Are you interested, classmates?"

Lu Liang's eyes twitched. He didn't expect that the other party would have such a move.

So Lu Liang made another random excuse and said in a nonchalant manner: "I'm sorry, I don't have time. My goal is to take the postgraduate entrance examination."

Lu Liang originally thought that if he used the postgraduate entrance examination as an excuse, the other party would give up.

But he never expected that after hearing this, the boy's eyes suddenly lit up, as if he saw some business opportunity.

The boy started talking: "Classmate, let me tell you, if you want to take the postgraduate entrance examination, you should know that English is a very important course!"

"If you don't learn English well, then the postgraduate entrance examination is just nonsense."

"We just happened to have an English interest class recently. There are foreign language teachers in it who specialize in teaching everyone to learn English. The registration fee is reasonable and fair. Are you interested, classmate?"

The boy finally came to his senses and started selling Lu Liang again.

The corners of Lu Liang's eyes twitched wildly. He really underestimated this man's patience.

If it were an ordinary person, they would have no patience to continue selling it, but the other party is like a piece of brown candy, and they can't get rid of it no matter how hard they are.

Lu Liang took a serious look at the boy in front of him for the first time: "Brother, I can't tell, but your business scope is quite broad."

The boy also waved his hand and said modestly: "This is nothing, brother, do you know the Lu Shen of our school?"

Lu Liang was stunned for a moment. Weren't you still selling courses just now? Why did it suddenly involve him? What does this have to do with him?
Lu Liang vaguely felt something was wrong, but he still nodded and asked, "I know, what's wrong?"

The boy started to boast: "Let me tell you, Lu Shen also participated in this English interest class we organized."

When Lu Liang heard this sentence, the look on his face suddenly became strange.

No, when did I attend an English interest class? Why didn’t he, the client, know about it?

Lu Liang asked tentatively: "Brother, is this a bit fake? Are you really sure that he has participated in your English interest class?"

The boy didn't blush at all when he told the lie: "It's absolutely true, brother, let me tell you, Lu Shen's evaluation of our English interest class is not low."

What the boy said was so serious that Lu Liang himself almost believed it.

After a moment of silence, Lu Liang asked again: "Brother, let me ask you again, are you really sure?"

The boy had no intention of changing his story. He even patted his chest and promised, "Brother, I can still lie to you. If you don't believe it, I can take you to see him another day."

Lu Liang sighed. He didn't expect that one day he would be used to deceive others.

Then, Lu Liang reached into his pocket and took out his student ID card and put it on the table.

Lu Liang's move made the boy a little confused for a moment, but he still subconsciously glanced at Lu Liang's student ID card.

However, when he saw the name on the student ID card, the boy fell silent and the expression on his face became wonderful.

Good guy, the deceiver has tricked the real owner.

The boy didn't expect that he would be hit by such a small chance.

After a moment of silence, the boy forced an awkward smile on his face. He was about to stand up and leave, but was stopped by Lu Liang: "How many people have you enrolled in your English interest class?"

"It's just started, we haven't recruited anyone yet." The boy replied weakly.

Lu Liang nodded. At least no one had been fooled yet. He said again: "I won't cause trouble for you this time, but I won't necessarily do it next time."

The boy breathed a sigh of relief, nodded quickly in assurance, and then trotted away.

After eating, Lu Liang also returned directly to the dormitory.

After arriving at the dormitory, Lu Liang turned on his computer and began to think about the three generations of evil.

There are actually many types of antibiotics, such as beta-lactam antibiotics, macrolides, tetracyclines, etc.

Without exception, these antibiotics are derived from the bacteria themselves and are natural.

With the development of science and technology, a kind of antibiotics has also been born. This kind of antibiotics is artificially synthesized, including oxazolidinone antibiotics.

The mechanism of action of third-generation evil on bacteria is also very simple.

If bacteria want to grow and reproduce, they must continuously synthesize proteins.

The third generation of nitric acid can bind to the 50s ribose subunit of bacteria, making it impossible for bacteria to use normal mRNA as a template for transcription, thereby inhibiting bacterial protein synthesis.

Compared with antibiotics such as penicillin, which have an antibacterial mechanism that destroys bacterial cell walls to achieve their goals.

Because of its brand-new antibacterial mechanism, most of the current Gram-positive bacteria are susceptible to third-generation evil bacteria.

Lu Liang created a new document on ChemDraw, and then began to draw the synthesis route.

The drug needs to use 3, 4-difluoronitrobenzene as raw material, and finally obtain the finished product through a series of reactions such as condensation, reduction, cyclization, hydrazinolysis, and acylation.

First, 3, 4-difluoronitrobenzene is dissolved in ethanol, then sodium carbonate is added and morpholine is added dropwise, and then palladium carbon is added as a catalyst.

After completing the reaction, the palladium on carbon was filtered, isoamyl acetate was added, and the reaction was carried out by raising the temperature and refluxing for 4 hours.

After the reaction is completed, add water, lower the temperature to 0°C, filter, and add dichloromethane, triethylamine and other compounds again to react.

After concentration to obtain the crude product, it was purified, and finally the third generation of evil was obtained.After Lu Liang finished drawing the drug synthesis route, he habitually opened the word document and started writing the patent.

The synthesis route and reaction conditions of the drug are all written in the patent.

By the time Lu Liang looked up from the computer, it was already dark.

Lu Liang rubbed his sore neck and then looked at the time. It was almost ten o'clock now.

It took nearly four or five hours to operate one bucket.

I spent the first hour drawing synthesis routes, and the next three or four hours were spent writing patents.

There is still a template, and it only needs to be modified based on the original one, and it has taken so long.

Lu Liang rubbed his eyes. After submitting the patent application on the website, Lu Liang stretched hard.

Then the next step is the old rule, ask Tian Li to let the factory synthesize some drug samples for testing.

This time, however, the focus of the experiment may have shifted slightly.

Because the medicine this time is antibiotics, animal testing is secondary, and the most important thing is to cultivate bacteria!
Lu Liang carefully recalled his previous experience of raising bacteria.

It feels like... yes, opening a blind box!

Others reap melons if they sow melons, and reap beans if they sow beans.

What you planted in the petri dish may be E. coli, but what it grows may be Staphylococcus aureus.

In a sense, this is indeed surprising.

But anyway, what has to be done has to be done.

Then he picked up his cell phone and dialed Tian Li's number, preparing to ask Tian Li to synthesize some samples in the factory.

Soon, Tian Li's voice came from the other end of the phone.

"Mr. Lu, it's really rare to see you calling me." Tian Li's laughter came from the other end of the phone.

"I can't help it, I'm quite busy." Lu Liang laughed and fooled him.

Tian Li stopped joking: "Mr. Lu, what happened to you this time?"

"What else can I do?"

Tian Li is also an understanding person. After hearing what Lu Liang said, he immediately knew the purpose of Lu Liang's call this time.

"No problem, Mr. Lu, just send me the things and I will arrange them as soon as possible."

"Then I'm troubling you, Mr. Tian."

Lu Liang clicked his tongue. Tian Li's work efficiency was still high. After communicating about the drug samples, Lu Liang was about to hang up the phone when Tian Li's voice came from the other end of the phone again.

"By the way, Mr. Lu, is there one more thing? I originally wanted to tell you later, but you just called me, so I'll tell you here."

"whats the matter?"

"Mr. Lu, do you have any ideas about our drug export?" Tian Li asked tentatively.

Export, go international?
Lu Liang paused. It was not like he had never thought about this issue.

But then I thought about it, and now I have offended those Western pharmaceutical giants in China.

With those pharmaceutical giants around, it may not be so easy for his drug to be approved by the FDA on the other side of the Atlantic, that is, the Food and Drug Administration of the United States.

Therefore, Lu Liang's attitude has always been to go out if he can, and forget it if he can't, whatever he likes.

But now that Tian Li raised this issue, he obviously had some solution.

So Lu Liang asked: "Mr. Tian, ​​do you have any ideas?"

After hearing Lu Liang's answer, Tian Li felt relieved.

In fact, he didn't know whether Lu Liang's attitude towards drug export was boycott or approval, so he thought of asking Lu Liang's attitude tentatively first.

Judging from Lu Liang's answer, his attitude is obviously in agreement.

Tian Li said excitedly: "That's it, Mr. Lu, a company in the West has found us and said it is willing to cooperate and hopes that we can authorize it to them."

In the field of medicine, the West is far ahead of China, so they have always been importing medicines.

But Tian Li never imagined that one day they would also be able to export drugs to the West.

How could Tian Li not feel excited about this? This was a great improvement.

Tian Li paused and then said: "To put it simply, it is a patent license. They will produce and sell it in the West, and the profits will be shared with us."

Lu Liang scratched his head: "This is not a matter of disagreement. Can they pass the FDA?"

Tian Li said: "They will be responsible for following up and handling this matter, so we don't need to worry."

"That's it."

Lu Liang nodded suddenly. After thinking for a moment, Lu Liang gave his answer: "That's okay, no problem."

Tian Li said: "In this case, I will contact them. After a while, someone will probably come over to discuss more detailed cooperation details."

"When the time comes, Mr. Lu, you can also come over and attend the meeting."

"Okay, I see."

After hanging up the phone, Lu Liang couldn't help but sigh.

He thought that with those Western pharmaceutical giants around, it would be impossible for his drugs to pass the US FDA.
But I didn't expect the turnaround to come so quickly.

Since the other party said that FDA matters will be handled by them, it naturally means that the other party is confident.

But then again, drugs can be sold.

But in terms of price
First of all, one thing that is certain is that the price of drugs must not be based on domestic prices!
After all, there is an old saying: Wei Junjie is the master of Western things.
No, it's crossed.

It should be called, when in Rome, do as the Romans do.

The standard of living on the other side of the Atlantic is high, and that's something the whole world knows.

After all, in the global per capita GDP ranking, the top ten countries are basically concentrated on the land on the other side of the Atlantic.

What does this mean? It means they are rich.

People are not short of money!
If you really sell your medicine so cheaply, wouldn't you be insulting others, thinking that they can't afford the medicine!

Therefore, when it comes to medicine, you have to follow the local customs.

So, the price of the drug.
Hey!

(End of this chapter)