Doctor Zhao, help!

Chapter 258 The silver lining

"To put it simply, the sour soup eaten by the patient was left for too long and deteriorated, causing the fermentation of rice yeast acid toxin."

"Riceobactic acid is a toxin produced by Pseudomonas cocotoxin and fermented rice flour subspecies that can cause food poisoning. It is the main cause of poisoning in fermented corn flour products, spoiled fresh white fungus and other spoiled starch products. "

Hua Min explained it carefully.

"Director Hua, if I remember correctly, the toxicity of zymomycin is mainly to increase the affinity between ADP and the inner membrane of mitochondria, blocking the transport of ADP, thereby inhibiting cellular respiration."

When Zhao Sheng heard what Hua Min said, he immediately thought of the main toxic mechanism of rice fermentation acid. Of course, this is not found in ordinary textbooks and is rarely mentioned in special toxicological literature.

"Yes, after rice fermentation acid poisoning, due to the lack of ATP, the ATP-dependent mechanism of the inner mitochondrial membrane stops working, causing water and sodium retention, which causes mitochondria to swell and the cristae to become shorter, blurred, and disappear."

"Mitochondria are an important place for respiration and energy exchange in cells and are the main energy supply organ in cells. The loss of its function will inevitably lead to the death of cells and organisms."

Hua Min looked at Zhao Sheng approvingly, then added something.

"Director Zhao, Director Hua, then the poisoning of this family was indeed caused by improper food preparation?"

Team Wu was confused by the professional terms used by Zhao Sheng and Hua Min, but he still grasped the key point. This rice fermentation acid toxin is indeed caused by bacterial fermentation.

In this way, other possibilities can be ruled out.

"Yes, Pseudomonas cocotoxin was also detected in the samples you sent. This is indeed caused by improper food preparation and preservation."

Hua Min nodded firmly and said.

Hearing Hua Min's affirmative answer, Team Wu and the team members who came with him also breathed a sigh of relief.

"Director Zhao, now that the cause of the poisoning has been determined, is there any way to cure it?"

Team Wu asked Zhao Sheng with another glimmer of hope.

However, at this time, he didn't hold out much hope. After all, four people in a family of six had been poisoned to death, and they didn't even make it to the point where they were sent here.

Therefore, it is hard to say whether the only two remaining people can survive.

"Captain Wu, if the cells of the human body are compared to a car, then the mitochondria are the engine. The main toxicity of rice fermentation acid is to destroy the mitochondria. Once the mitochondria are completely destroyed, the possibility of recovery is very small."

As a toxicology expert, Hua Min couldn't help but explain it to Team Wu.

"Then it's not hopeless..."

Team Wu said with a gloomy expression.

"Not necessarily. If the patient's mitochondria are all inactivated, it will be too late to be sent here."

"Director Hua, I remember that part of the toxic effect of rice fermentation acid is the inactivation of thiolase, so can we use thiol compounds such as L-cysteine ​​to restore the thiolase activity inhibited by rice fermentation acid and alleviate the problem? The toxicity of part of the rice fermentation acid creates time and opportunity for the remaining mitochondria to recover."

An idea flashed in Zhao Sheng's mind, and a document he had read appeared in his mind.

"Theoretically, this is possible, but there are no clinical success stories."

Hua Min thought for a while and said seriously.

"Just the possibility is enough."

Zhao Sheng said very firmly that as a doctor, as long as there is any possibility in clinical practice, he cannot give up.

"Team Wu, Officer Song, I won't accompany you anymore."

After a pause, Zhao Sheng said to Team Wu and Officer Song.

"Okay, Director Zhao, go quickly."

"I'm fine now."

Team Wu said quickly.Now that the cause of the poisoning has been determined and the possibility of man-made causes of this horrific food poisoning incident has been ruled out, his mission has been completed.

Zhao Sheng didn't care about being polite anymore and quickly returned to the ward.

"Director Zhao, is there any news from the Toxicology Department?"

As soon as Zhao Sheng came in, head nurse Zhou Hong asked, and Li Mujia also looked at Zhao Sheng.

"Ah."

"Dr. Li, use cysteine, high dose."

Zhao Sheng nodded and said to Li Mujia.

"The patient is determined to be suffering from rice fermentation acid poisoning. The only hope now is to use large doses of sulfhydryl compounds to reduce the toxicity of rice fermentation acid and wait for the mitochondria to slowly return to normal levels."

After a pause, Zhao Sheng briefly explained to Li Mujia.

"it is good!"

Li Mujia nodded and went quickly.

15 minute later.

After setting up the medicine pumps for both father and son, Zhao Sheng and Li Mujia breathed a sigh of relief. Now they just waited to see if this large dose of cysteine ​​would have an effect.

In fact, this is a bit like treating a dead horse as a living horse, and fighting for a glimmer of hope.

The fact that these two patients were able to be sent here shows that they ate less at that time, received a small dose, and the mitochondria in their bodies were not completely destroyed by toxins.

Therefore, after the toxic reaction is alleviated, perhaps the remaining mitochondria can slowly recover.

There is a damage threshold for mitochondria in the human body. Once the damage exceeds this threshold, the damage is irreversible.

But if the mitochondrial damage is above this threshold, then it is possible to recover. To put it bluntly, it is now a matter of luck and hard work.

Zhao Sheng and Li Mujia just sat beside the hospital bed, observing the changes in the condition of the father and son.

"Dr. Li, you go and take a nap. I'll just keep an eye on you from here."

Zhao Sheng looked at the time and saw that it was already three o'clock in the morning. Although Li Mujia was on duty, staying up all night was still very bad for the body.

It would be best to take a break in between.

"Director Zhao, do you think I can sleep now?"

Li Mujia looked at Zhao Sheng and said.

Although she has been busy since 08:30 in the morning, Li Mujia's face is only slightly tired. It is because of her hard work that she can get out of the small town and have her current work and life.

Although the work is tiring, Li Mujia feels it is worth it compared to being trapped in a small town for the rest of his life.

"That's true. After twelve o'clock, the quality of sleep is actually very poor."

Zhao Sheng nodded.

Waiting now is also waiting. Zhao Sheng couldn't help but study the new function he discovered. When he was doing surgery before, he had a wonderful [connection] state with other doctors, the kind that allowed him to be immersed in the scene. Perceive other operations and then cooperate with them.

But recently, as he has cured more and more seriously ill patients, in addition to physical strengthening, Zhao Sheng has discovered that this [connection] function seems to have a new use, that is, to [connect] him to other people and then share them. Energy and endurance.

In other words, he can act as a humanoid power bank at any time, charging other people, so that others can be energetic at any time.

(End of this chapter)