The road to the rise of great doctors

Chapter 42 Various Medical People
Zhu Guoliang smiled after hearing this, and said to Liu Dong: "There are not only doctors, nurses, and technicians in the hospital, but also many different roles. For example, if the department wants to carry out clinical research, it needs to do a good job of follow-up. Some hospitals Doctors or nurses call patients for follow-up visits, but because they are not full-time personnel, the recorded data will be sloppy, and when it is actually used, we will find that there are not many uses, which is a pity."

"Some hospitals or departments that are good at clinical research have recruited full-time personnel. In addition to follow-up, sample collection, image collection, etc., they will also establish their own database and enter the follow-up data into the database for backup. Departments with more financial resources, We will apply to establish a research institute and recruit statistics professionals and clinicians to specialize in scientific research."

"In addition, there are field staff, nursing staff, administrative management, finance, etc. in the hospital. Back to the clinical front line, when conducting clinical trials, we encounter more CRC, CRA, CRP, project managers, etc. They will regularly come to the hospital to monitor or audit the data in accordance with the research plan and the requirements of the regulatory agency."

Zhu Guoliang took a sip of water, paused, and continued:
"Look, that cabinet is specially used to store clinical trial materials. That girl is the 'Clinical Research Coordinator', often called 'Little C'. The English abbreviation is 'CRC', which is the researcher's most powerful tool in clinical research. The left and right hands."

"Many of these positions are taken by nursing majors who have not become nurses, or who have changed careers in pharmacy. Generally, they require a basic medical or related professional background. After receiving training, they can take up the position after being authorized by the principal investigator. The main The job is to assist researchers in non-medical judgment work in clinical trials. Of course, different people have different levels and understandings, and the mobility of positions is relatively high, with frequent replacements."

After listening, Liu Dong was still quite shocked.

He knows that many medical conclusions, guidelines, and consensus are based on research results from clinical trials.

Liu Dong was full of interest after hearing about it for the first time.In his mind, these are all components that help clinical practice and enrich disease treatment methods.If a doctor wants to grow quickly and eventually become a "great doctor", he must be good at using all available means, learn more and think more, so that he can stand high and see far. When encountering difficulties, others cannot help him. Preparation may be difficult, but if you are prepared, you may be able to solve it with ease.

That day, after Liu Dong went back, he looked up some information and carefully understood the work content of these "medical personnel" who were not hospital employees:

Medical judgment is the work that doctors should do. Little Cs help deal with non-medical judgment and are very important front-line workers.

For example, when a patient in a clinical trial needs follow-up, she will call or send messages to the patient to arrange the examination items for follow-up. After the results come out, they will be interpreted by the research doctor, and then the results will be recorded, etc.Patients participating in clinical studies can also contact them directly if they have any questions. They will collect the information and provide it to the research doctor in a timely manner, and then reply to the patient with a treatment plan.

Indeed, the clinical work is so busy, if the research doctors do it by themselves, on the one hand, the efficiency will be slow, which will affect the progress of clinical research; on the other hand, the research doctors have no time to answer the phone or reply to messages during operations or outpatient clinics.A lot of work that doesn't require such a professional knowledge reserve is done by doctors, which is not worth it.

It is also in line with the "market economy" to leave key medical judgments to doctors and assistants to do other work.

In addition to checking the information, Liu Dong also talked about this issue with a research doctor who actually participated in the clinical study.

The doctor said meaningfully: "It is because of the diligent work of the little Cs who are fighting on the front line that all clinical trials can run normally. In the hearts of most researchers, they are the well-deserved harem of every clinical trial project. The lord of the palace is the same as the researcher regarding the six palaces of the East and West.”

Liu Dong spread his thoughts and recalled the language used by many medical experts when talking about topics such as "integration of medicine and engineering" and "transformation of medical achievements", and he had some own views and understandings on these.

Clinical trials are a typical example of the integration of medicine and industry in the medical community and industry.The development of modern medicine no longer focuses on working alone, but hopes to achieve breakthroughs in cross-field cooperation, including but not limited to the cooperation of clinical medicine and basic medicine, and the complementarity of medicine and life sciences.
At present, domestic clinical research has just started, and we are still learning from abroad, learning systems, learning cases, and learning ideas.

For new drugs or new devices, clinical trials must be conducted before regulatory approval is obtained for marketing.Excellent data obtained through clinical trials are necessary to support product launch.

The more Liu Dong understands, the more reasonable he feels.This is also very inspiring for his planning of medical development.

Liu Dong was interested in clinical trials, but he also understood that as an intern, he could not participate in much.Understanding more now will be beneficial to future development.In the later stages, you may be able to gradually participate.

Clinical trials are particularly important in cancer or other areas where current treatments are limited.It is also in line with the general direction of national development.

Taking cancer as an example, current cancer is mainly treated with surgery in the early stage, and chemotherapy or radiotherapy in the late stage.For some diseases, targeted drug therapy shows better efficacy data than chemotherapy.

However, the overall efficacy data for advanced cancer are still unsatisfactory.

Among them, after the diagnosis of advanced cancer, the research data on the first-line drug treatment adopted at the beginning is now the most complete.It's easy to understand, because when you get a disease, you have to make a choice about the first treatment. Which one is better and which one can live the longest is the current first-line standard treatment plan.

Of course, what is mentioned here is that the patient's general condition, physical condition, etc. are not bad and can withstand these treatment plans.For advanced cancer, these treatment options are, in a sense, "killing one thousand enemies and damaging oneself eight hundred." Chemotherapy, for example, affects both cancer cells and normal cells.For those who cannot bear these anti-tumor treatment options, they have reached the stage of "running out of oil and lamps". The best way is to provide symptomatic and supportive treatment to reduce pain.

So, now that the first-line treatment has a relatively recognized plan, what about the subsequent treatment plans?It is also gradually improved.Many cancers have standard second-line regimens, and even third-line regimens are recognized as good.

However, there are many that are inconclusive.For those who have a conclusion, just follow the current optimal treatment plan first, and continue treatment until the treatment is ineffective, the disease progresses, or the side effects are too strong and cannot be tolerated.

　Newbie, new book, thank you guys for your attention and love.Please collect, recommend, vote, thank you...

　　


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