I run a clinic in the United States

Chapter 43 Four-Drug Combination of FOLFIRINOX Regimen
Zhou Qiao said: "That's probably what it means! Although this disease is difficult to cure, it requires the patient's close cooperation. At the same time, you must have a strong desire to survive. If you give up on yourself and feel that there is no way to save it, no matter how powerful I am, I can't help it." I can't help you!"

"Well, Doctor Zhou, we will treat you here, please be careful! Thank you!" Mr. Clark said very sincerely.

Mrs. Clark nodded too.

"No problem. In fact, because your condition was discovered in time, there is a certain probability that it can be cured. Let me explain to you the plan and the things you need to pay attention to in the early chemotherapy. After one or two courses of treatment, we Evaluate the effect of chemotherapy, if the effect is good, you can carry out surgical resection.

Of course, after the operation, appropriate chemotherapy and consolidation should be carried out.This is a long process with many physical and psychological challenges, but no matter what, we must have confidence!Believe me, you will be able to overcome the disease! "

"Yeah," Mrs. Clark nodded and said, "If we don't believe you, we won't come back!"

After a group from the University of California Medical Center, Zhou Qiao's superb medical skills have penetrated into their hearts, and their admiration is beyond words.

After all, this is to challenge the existence of the entire expert group by one person.Although, Zhou Qiao looks so young!However, they believe that there is no shortage of geniuses in this world, and it is obvious that Zhou Qiao is such a person!

Then, Zhou Qiao immediately asked Ava to arrange chemotherapy for Mrs. Clarke.

As for the drugs needed for chemotherapy, they can be easily obtained from the supplier.This is an international metropolis, not a remote small clinic in China.

The first floor was too noisy and people came and went, so in the ward on the second floor, I chose a south-facing room for Mrs. Clark to lie down comfortably for chemotherapy.

In the early stage of neoadjuvant chemotherapy, Zhou Qiao chose the FOLFIRINOX regimen, that is, oxaliplatin + irinotecan + leucovorin + 5-fluorouracil, a course of treatment every 2 weeks.

Why should neoadjuvant chemotherapy be given before surgery?
Simply put, it is chemotherapy used before surgery or radiotherapy. Some tumors are difficult to be removed by surgery or eradicated by radiotherapy because of large tumors or obvious adhesions to surrounding tissues. 2 to 3 courses of chemotherapy can be given first to shrink the tumor. Change the unresectable to resectable, or change the radiotherapy range to a relatively small radiotherapy range.

In addition, there are some other reasons, such as surgical resection of the primary tumor may stimulate the growth of remaining tumor cells; after surgery, the blood supply of the tissue around the tumor changes to some extent, and some blood vessels are interrupted, atresia or stenosis, which affects the concentration and effect of chemotherapy drugs.Wait, I won't repeat them one by one.

This chemotherapy regimen has the best effect on pancreatic cancer, but because it uses many drugs and the side effects of each drug are relatively large, it is suitable for patients with relatively good physical fitness.

For example, irinotecan may cause severe diarrhea, and some patients may have watery stools, while fluorouracil and oxaliplatin can easily cause peripheral inflammation.

In addition, this treatment plan is also prone to myelosuppression, such as white blood cells, red blood cells, thrombocytopenia, etc., so when using this chemotherapy plan, it is necessary to pay close attention to the adverse reactions of patients.

The blood routine should be done at least once a week, and the blood routine should be checked the next day after the injection.

The reason why Zhou Qiao chose this plan was naturally after professional evaluation.There are two other alternatives, but they are slightly less effective.

However, with this type of chemotherapy, patients are prone to drug resistance. If the first regimen doesn't work, it is very necessary to switch to the second regimen, or even the third regimen!

Four drugs are used in combination, some are intravenously pushed, some are pumped, such as fluorouracil, which needs to be infused continuously for 46 hours, and then the adverse reactions must be closely monitored during the whole process. Therefore, Mrs. Clark will stay in the ward of the Iris Clinic tonight. .

Ava turned on the TV and took an iPad as a spare. If you get bored watching TV, you can also play small games on the iPad.

"Mrs. Clark, if you are thirsty, remember to drink the hot water in this boiled water bottle. This is specially explained by Dr. Zhou. He said that you can't touch anything cold, especially drinking cold water, eating cold food, and blowing cold wind. Go home Try not to touch the refrigerator afterwards." Ava has blond hair, blue eyes, white skin, wearing a nurse's uniform, like an angel who descended from the sky.

"Why is that?" Mrs. Clark wondered.

Because Americans have never had the habit of drinking hot water.Even if some people drink tea, the kind that is brewed with boiling water, they still put ice cubes in the tea, or put it in the freezer before drinking it.As for cold water instant tea and canned tea, it goes without saying that there is no ice and no joy.

Only the Chinese in Chinatown will boil the water and drink it warm!In particular, some people like to soak wolfberry in a thermos.

Ai Wa smiled and said: "Doctor Zhou said that drinking hot water can cure all diseases." She remembered that when she had her period a few days ago, Zhou Qiao suggested that she drink hot water.

Seeing that both Mr. and Mrs. Clark shook their heads, expressing their disbelief, Ava had no choice but to quote Zhou Qiao’s other explanation: “Well, Dr. Zhou said, it’s actually because the drug oxaliplatin has peripheral nerve toxicity, which will cause Numbness of hands and feet and other extremity sensory disturbances or paresthesias. In severe cases, there will be cramps and even loss of sensation in hands and feet. These symptoms will be aggravated if they encounter cold, so drink plenty of hot water and avoid contact with all cold things. !”

"Oh I got it!"

"If you put it that way, we will understand!"

"It's no wonder that Chinese people like to drink hot water. I couldn't understand it before, but now that I think about it, the wisdom of the ancient Chinese is really hard to fathom."

Mrs. Clark, whose health is important and never drinks hot water, also tasted hot black tea for the first time, and was full of praise.

I was not used to it at first, but after a few sips, I couldn't put it down.It is worth mentioning that since then, Mrs. Clark fell in love with drinking hot water and became an alternative American!
"Mrs. Clark, take it easy. Smile often. A good mood is very helpful to your condition. Well, you are here on vacation. If you need anything or feel uncomfortable, call me anytime! The bell next to the bed will do!"

Ava smiled, and brought a lot of snacks, and then some of today's latest newspapers.

Mr. Clark nodded, this kind of service is really much better than big hospitals, and the total cost is lower.

After Ava went out, Mr. Clark asked, "Deborah, do you want to call our daughter? Why don't you inform her of your serious illness?"

Mrs. Clark took a sip of the steaming black tea and said, "Then give her one."

So Mr. Clark picked up his cell phone and dialed it.

Their daughter, Jessica, is not in San Francisco. After graduating from Harvard University, she went to New York to work for a large multinational company.Although, there are a lot of flights in the United States.

When the phone was connected, Mr. Clark didn't know how to speak for a moment: "Jessica..."

He just called his daughter, and as a result, Jessica's very impatient voice came from the other end of the phone.

　Thanks to the book friends who voted monthly!
　　If you have tickets, I'd be very grateful if I throw in a few.

　　As for the explosive update, I guess we have to wait until it is released.Because the early updates are so fast, it’s easy to be placed on the new book list.
　　
　
(End of this chapter)