Traveling through the 80s, the beauties in the courtyard can't be provoked

However, after hearing the news, the head teacher and the subject teacher all came to persuade her.

Even if you can play well, even if you are recognized by everyone in the academic world, the brand is different after all.

Just like the same thing, even if it is produced by the same manufacturer, but with different trademarks, it will give everyone a different feeling.

Li Shenglong's results and choices were really ruined.

Tsinghua University, Peking University, even Tongjin University, all have bonuses.

The amount is quite a lot.

Li Shenglong changed his mind and the bonus was gone.

Li Shenglong bowed deeply to the teachers and said: "Thank you teachers for taking care of me. I know you are doing it for my own good, but my mother is injured and I can't go far."

Everyone was relatively speechless. They started to speak but stopped, and finally sighed helplessly.

The principal patted Li Shenglong on the shoulder and said, "Fortunately, it's not too late. Come on, Shenglong."

it is good.

Come on, she goes.

Where there's a will, there's a way, and Li Huixian will be fine.

After Li Shenglong came out, Wei Yanzhi was holding his bicycle and waiting for her at the school gate.

As soon as Li Shenglong walked up to him, he pulled her into his arms with one hand.

He didn't say anything, but Li Shenglong could feel his warmth and support from his arms.

Li Shenglong left Wei Yanchi's arms and said, "There is no time. We will build a drug research and development laboratory from now on. We will make chemotherapy drugs."

"Chemotherapy drugs? Shall we do it?"

Yes, let alone targeted drugs, they don’t even have chemotherapy drugs now.

Their technology is already very good for producing antibiotics independently.

Being backward is just that.

Therefore, Li Shenglong cannot talk about targeted drugs because no one has this concept.

It can only be said to be chemotherapy drugs.

However, targeted drugs did evolve from chemotherapy drugs.

Chemotherapy drugs work by killing cancer cells but leaving cells that grow slowly.

Because the difference between cancer cells and normal cells is that cancer cells grow and multiply rapidly and will replace normal cells and occupy every corner of the body.

However, there are also normal cells in the human body that grow quickly, and chemotherapy drugs will also kill normal cells that grow quickly.

So hair will fall out during chemotherapy.

Based on this phenomenon, scientists wonder if there is a chemotherapy drug that can accurately attack cancer cells and only attack cancer cells.

Later, with the development of science and technology, biology also became more sophisticated, and scientists modeled the working principles of targeted drugs in computers.

Then the development of targeted drugs began.

Targeted drugs target the identified carcinogenic site at the cellular molecular level. This site can be a protein molecule inside the tumor or a gene fragment.

The principle of targeted drug treatment is that drugs often have to enter the inside of cancer cells, or specific organelles, such as mitochondria, cell membranes...

Sounds simple.

But in the development process, this is the difficulty.

How to get inside the cell?

Modern medicine generally has two methods, passive or active, to bring the drug to the carrier, and the carrier is passively loaded or actively combined with the internal points of the cell.

At this point, it is already difficult, because the scientific and technological power is simply not enough to support such a novel research and development project.

Today, in the country, there is only one NMR instrument that can even perform structural confirmation.

There is only one in Shanghai.

But I can’t take care of that much anymore, so let’s set up the project first.Li Shenglong said: "Yes, if we do it in a pharmaceutical factory, we don't know when the project will be approved, and my mother can't afford to wait."

Although Wei Yanchi nodded, he was worried: "Shenglong, is it too much money? Can we really do it?"

Yeah, can they really?

The country's pharmaceutical industry has always lagged behind. Even in post-modern times, there are very few new drugs available and they are all being copied.

How backward is it?Targeted drugs have been developed abroad, but they can't even get the simulation programs in school textbooks.

The biggest fundamental problem here is money.

Drug research and development requires a huge investment, and even if it is successfully developed, it will take many years of clinical trials before it can be put on the market.

Clinical success is lucky. If the clinical trial fails and the drug cannot be used, hundreds of millions of R&D funds may be wasted.

Few people in the private sector can spend so much money, or are willing to spend so much money, to do such uncertain things.

Therefore, private companies are obsessed with generic drugs.

The so-called generic drugs are drugs whose foreign patents have expired. Their structural formulas are public and can be copied by various countries without the need to pay patent fees.

That is to say, someone else always starts to organize research and development two years before the expiration date, and then develops the finished product. When it is due, they will be the first to apply for approval. Whoever gets the approval first will occupy the market, so that they can make money.

Otherwise, what will the new drugs they develop look like?
For example, acetaminophen, a very mature antipyretic drug, is added to traditional Chinese medicine preparations and given a trade name, and it becomes a new drug.

Otherwise, combine three compound chemicals into one and give it a trade name, like 666, Little Chrysanthemum...

Whatever, it’s a new drug.

I’ve been doing this forever, how can I not fall behind?
But there is no way, private companies really cannot spend hundreds of millions for research and development.

What about state-owned enterprises?
Aren't they obsessed with developing 'new drugs' and changing their trade names?

They have no responsibility, rely on private enterprises and have no money.

In fact, there is another way of research and development, which is university laboratories.

But in the environment of later generations, I don’t know where the money went.

In fact, overall, it is still a relatively good time.

Mr. Zhong can now focus on making vaccines as long as the country supports it.

So they set up the project now, and then they can show the project document to various influential laboratories. Maybe someone has the foresight in this regard and appreciates their project very much.

Once they invest in research and development, they can change the current situation in which the pharmaceutical industry has always lagged behind.

Hope suddenly arose in Li Shenglong's heart. She said: "Both the beverage factory and the plastic factory are profitable. I still have some money in my hand. If it is not enough, I will go to the bank."

"But I have to send my mother to see a doctor first. You can help me choose a factory location, and we'll talk about the rest after I come back."

Wei Yanchi felt that it was quite difficult for them to do this, mainly because there were too few manpower, but it was all serious business, and it was not about eating, drinking, whoring and gambling. What can I do, just do it while you are young.

After Li Shenglong went back, he thought about it and went to find Director Yan.

"Factory director, can you give me a letter of introduction and the title of purchasing director? Don't worry, I don't want the factory to pay me a salary. I'm going to the south this time and want to purchase two experimental instruments."

"What experimental equipment do you want to purchase?"

Li Shenglong himself didn’t know this.

She wants to buy liquid chromatography and infrared chromatography.

I'm afraid none of them are for sale now.

But go give it a try.

Director Yan has heard of it but has never seen it.

He knew the importance of this thing and said to Li Shenglong: "I heard that Shenzhen is changing rapidly. If your mother is not seriously injured, you can also go and have a look to see what advanced equipment their pharmaceutical factory has. Write it down and come back. Give me a report."

I stayed up late yesterday, so I’ll just update one today. Just treat it as the eleventh day and I’ll have a holiday.

Goodnight everybody.