People in Hongwu, from heavenly master to emperor master

Chapter 535 Artemisinin, they are nothing

In the spring of the tenth year of Hongwu,

Dragon Tiger Mountain.

Zhang Yi checked Lao Zhang's pulse and prescribed some medicine for him.

Lao Zhang's face became a little rosy, but Zhang Yi could still feel his life force gradually passing away.

He hid his sadness, but at the same time he was somewhat relieved.

At least, the situation is better than I imagined.

"You should go..."

Lao Zhang pulled his hand back and smiled gently.

Zhang Yi stayed in Longhu Mountain for nearly half a year this time.

He was able to stay for so long because of himself.

But Zhang Chenggong understood that he could not keep his child.

Zhang Yi nodded silently and said:

"Yes, if I stay any longer, His Majesty will send someone to rush me...

Dad, I will write you another prescription, and together with the medicine I will make for you later, it should have a good effect..."

Zhang Changsheng smiled and said:
"Okay, Pindao still wants to live to see you get married and have children, or..."

His smile moved Zhang Yi even more.

"How about I go see big brother?"

Zhang Yi stood up, said goodbye to Lao Zhang, turned around and left.

He knew where Zhang Yuchu was and walked over.

Zhang Yuchu rarely came out of the Longhu Mountain Research Institute since he knew something was wrong with Lao Zhang.

He was already a famous genius in the history books. After he calmed down and was not disturbed by external things, Zhang Yuchu quickly devoted all his energy to the research of Zhang Yishuo.

When Zhang Yi found Zhang Yuchu, Zhang Yuchu was full of excitement.

"It became..."

"what?"

"The artemisinin you mentioned..."

"Really?"

Zhang Yi's eyes widened in disbelief.

Zhang Yi was conducting research on artemisinin at Longhu Mountain and Chunqiu College at the same time.

With a version of the answer, actually making this drug is a long process of trial and error.

Limited by the technological level of ancient times, their trial and error process was much more difficult than that of later generations.

However, Zhang Yi stands on the shoulders of giants. With a way to rely on, at least he will not be confused or take the wrong path.

But even so, Spring and Autumn College has not yet developed artemisinin. He did not expect that his elder brother had researched it in advance.

"It should be right. If what you said is correct, this is artemisinin!"

Zhang Yi took the sample handed over by Zhang Yuchu and was filled with joy.

"With this thing, the chance of bargaining with His Majesty is much greater..."

Zhang Yi smiled happily, and Zhang Yuchu was confused:
"Isn't it just a medicine? How can I make His Majesty look at me differently?"

"Artemisinin targets malaria... Brother, you are in Longhu Mountain, so naturally you don't know how terrible the mosquito miasma is in the south..."

Malaria had almost no presence in Zhang Yi's later generations.

Even in the south, where ancient people believed that miasma was common, this disease has almost disappeared because of the government's efforts to eliminate the four pests.

But in poorer countries, malaria still kills a large number of people.

It was still an era when medicine was developed, hundreds of years ago in the Ming Dynasty.

The harm of malaria is no less than that of a plague.

Zhang Yi smiled and said:

"The gadgets in our hands may not play a decisive role, but at least they can help Ming attack the Indo-China Peninsula and establish rule, saving a lot of costs!

You don’t know that if you fight in the rainforest, a malaria attack may take away the lives of thousands of people.

With artemisinin, the problem of malaria can be effectively solved!

This will not only benefit the people, but will also be a huge help to our war in the next year! "

In the strategy that Ming Dynasty gave Zhu Yuanzhang, Indochina must be captured.

If placed in a farming society, this place would actually be useless, and the Central Plains dynasty had little interest in it.

The tropical rainforest climate brought infectious diseases that were difficult for ancient people to deal with...

And because of the lack of fertilizers, tropical food production is actually not much higher.

At this time, including India in later generations, it was not considered a very good food site.

The southern region's advantage in grain cultivation only gradually emerged after the emergence of chemical fertilizers.

In such a place, even if the Central Plains Dynasty was conquered, it would be difficult to establish effective rule. ,
In order to control the origin of rubber, Ming Dynasty had to turn this place into its own land.

Rubber, in the early days of the industrial revolution, was industrial gold and a necessary strategic material!

We can't rely on Hainan Island or let vassal countries grow this kind of thing, right?
Rule, rule, must rule.

He also knew that Wang Baobao was already in Hainan, waiting for an opportunity to capture the Indochina Peninsula by sea or land.

It is not easy to conquer this place. Maybe Lao Zhu has not realized it until now.

Infectious diseases such as malaria can take away the lives of Ming soldiers on a large scale.

Not to mention soldiers, no matter how famous your generals are, malaria can be taken away by you equally.

Under Zhang Yi's explanation, Zhang Yuchu also realized the benefits of what he was holding.

"Brother can personally give this gift to His Majesty..."

Zhang Yuchu was shocked when he heard this. He thought Zhang Yi wanted to dedicate this thing to the emperor in exchange for him getting back the title of Heavenly Master.

Who would have thought that Zhang Yi had no intention of using it himself?

“Brother, you also need to build some qualifications for yourself!

His Majesty is different from other emperors in that he also believes in things involving gods and ghosts.

But he values ​​things in reality more, and being able to make real contributions will be of great use to you in taking over your father's position in the future..."

Zhang Yuchu was stunned. Zhang Yi's words were tantamount to telling him that he had no intention of inheriting the mantle of Longhu Mountain?

He glanced at Zhang Yi blankly and found that his expression was calm, and he finally understood Zhang Yi's thoughts.

"it is good……

I'll do an experiment first to make sure everything is safe! "

Zhang Yuchu nodded silently. Between brothers, there are many things that do not need to be thanked.

"This medicine also has some effect on my father's condition, although it is not very effective..."

Zhang Yi reminded Zhang Yuchu in a low voice that artemisinin is the main anti-malarial drug, but it is not just anti-malarial.

It also has an auxiliary effect on diseases such as tumors and diabetes.

For future generations, it may not be the best choice, but when there is no choice, it is always an option...

After making an agreement with Zhang Yuchu, Zhang Yi went back to report to his father.

After hearing that what Zhang Yuchu had created could achieve such great success, Zhang Changsheng was also full of information.

Although his body bones are a bit weaker now, he is not so sick that he cannot walk.

"You go back to the capital first. Later, Pindao will also go to Nanjing in person. When the time comes, he will bring your elder brother with him..."

Lao Zhang is very open-minded about his own affairs.

What he hopes is that the next generation can continue the incense of Longhu Mountain and pass on the things left by their ancestors.

"Don't forget, dad still wants to consummate your marriage!"

"This is not in a hurry!"

"You're not in a hurry, aren't the other girls in a hurry?
Okay, it’s not up to you to arrange this matter..."

After the matter was settled, Lao Zhang blasted Zhang Yi out with a smile.

After Zhang Yi left, his eyes dimmed.

"It's good, no regrets..."

There was only a faint sigh left in the room.

Zhang Yi finally went down the mountain. Zhang Changshang didn't see him off, and he also took his two younger brothers with him.

"Zhang Yi, dad is really..."

Zhang Yuchu was still a little unwilling when he left.

Zhang Yi sighed and shook his head.

"I'm not sure about the method of surgery...

It’s better to let nature take its course! "

He once mentioned Hua Tuo's surgical treatment of bone scraping to Zhang Yuchu, which also ignited Zhang Yuchu's hope.

However, Zhang Yi himself rejected this idea in the end.

Even though he has abnormal muscle memory, he doesn't understand medicine.

What's more, it is such a complicated surgery. In the ancient environment, not to mention the problem of resection, even subsequent infection is likely to take away Lao Zhang.

After it was determined that it would not work, the disappointment on Zhang Yuchu's face was beyond words.

"Okay, leave the house to me. You can take your brother and the others there with you..."

Zhang Yi nodded silently, then turned and left.

Zhang Yuchu watched his carriage and horses disappear at the end of the road. He walked not far away when a team came towards him.

Zhang Yi took a closer look and saw that the man in the flying fish suit was actually a Jin Yiwei.

"Master National Teacher!"

The man leading the Jin Yiwei was none other than Zhang Yi's old acquaintance and friend, Zhou Tong.

Zhang Yi was also happy to see him.

However, the identity of the two people should not be overstated.

He just smiled:
"Master Zhou, why are you here?"

"Returning Master, Your Majesty asked me to invite you back to the capital..."

Zhang Yi was speechless. Sure enough, his guess was right.

He stayed in Longhu Mountain for less than half a year, and the emperor really wanted to let him go back.

If you go down the mountain now, you can take the initiative to return to Beijing, right?
"It's enough for Your Majesty to write a letter. Why do you need Mr. Zhou to come in person?"

Zhang Yi smiled and greeted Zhou Tong.

Who would have known that Zhou Tong said something meaningful:
"Perhaps His Majesty is worried about the safety of the Imperial Guard on the road, right?"

"In the territory of Ming Dynasty..."

Zhang Yi wanted to say something polite, but suddenly shut up.

Is the territory of the Ming Dynasty necessarily safe?

Between the ancient settlements and settlements, there were a large number of uninhabited wild places.

But when Zhou Tong said he was worried, that was definitely not what he was talking about.

Zhang Yi glanced at Zhou Tong meaningfully. The two did not speak. Zhang Yi tacitly asked his team to follow the Jin Yiwei.

Under the escort of Jin Yiwei, they headed towards Yingtian Mansion.

Resisting the urge to ask each other for advice, Zhang Yi and Zhou Tong finally arrived near an inn.

Jin Yiwei went in to control the situation, and Zhang Yi and the people in Longhu Mountain settled down.

At this time, he had the opportunity to ask Zhou Tong.

The two of them were sitting alone, Zhang Yi asked:
"Is the situation outside so bad?"

Zhou Tong smiled bitterly and said:

"Master Zhang, do you still have the nerve to say that?

The matter of rectifying the officialdom has affected the interests of many people!

Not to mention the storm in the court, there are more than a hundred people who regard you as a thorn in their side?
Your Majesty also feels that this Yingtian rumor is wrong, so he specifically asked us to protect you!
Otherwise, if you fall into the water or encounter bandits along the way, no one can tell..."

Zhang Yi: ...

It seems that he has really reached the point of anger and resentment.

However, he also understood that the path he took was still a bit hasty after all.

Zhang Yi has always believed that changes in social relations are rooted in changes in productivity.

As long as it is still an agricultural society, the current social system of Ming Dynasty may not be the optimal solution, but it is at least one of the optimal solutions.

All his reforms are based on the technology he contributed, which has actually affected the operation of social economy.

Just like business tax reform, such as attempts at industrialization.

But Zhang Yi is not sure whether these changes can keep up with the pace of reform.

In his opinion, if it hadn't been for Lao Zhang's incident, Zhang Yi would have spent five to ten years gradually influencing the emperor...

But it was too late to say anything at this time. The arrow was on the string and had to be fired.

"At the imperial court, after the emperor revealed the news, even Mr. Li took the initiative to come to Beijing!

However, Mr. Li's persuasion to His Majesty was in vain. Actually, the emperor and Mr. Li had a quarrel in the imperial study room at that time.

Mr. Li said that His Majesty is a single husband, and that scholar-bureaucrats and kings share the world..."

"Forehead……"

Zhang Yi was quite speechless when he heard this. A scene from the TV series actually happened.

Li Shanchang was really anxious to be forced into this situation.

"Your Majesty's answer is that I share the world with the people?"

"The Imperial Master really knows things well..."

Zhou Tong gave Zhang Yi a thumbs up, and Zhang Yi couldn't laugh or cry either.

History was ruined by him.

Regarding the concept of "people", Wen Yanbo revealed the unspoken rules hidden in the hearts of scholar-officials throughout the ages.

Although the scholar-bureaucrats often threatened the emperor with the support of the people, they also kept the people in mind.

But the so-called popular sentiment is actually the sentiment of the scholar-bureaucrats.

The so-called people are nothing more than the entire elite and gentry class.

The people under them are like dogs, and they are not worthy of the word "min" at all.

Although this sentence has been famous throughout the ages, it is rarely said on people's lips.

No matter whether they are kings or scholar-bureaucrats, everyone knows it well, but they will not reveal the truth.

The common people have never been considered by the ruling class, but Zhu Yuanzhang, the emperor, is an outlier.You say he loves his people like his own children, is that true?
He also exploited people in the history books.Faced with the interests of Lao Zhu's family and the interests of the people, Lao Zhu would definitely choose the former without hesitation...

But if you say he doesn't care at all, you can't say the same.

At least Lao Zhu really wants to work hard to change the living conditions of the people...

No emperor would say to his Zhongcheng that the king and the people share the same world...

"So, the relationship between His Majesty and the monarch and his ministers is now very tense!"

"At least that's the case with Mr. Li. A single word from Mr. Li was equivalent to ending his political future. The emperor originally wanted to kill him, but thinking of his merits, he let him go after all...

However, it was also because of Mr. Li's incident that the discussion on this matter in the court calmed down.

That is, the silence of all the officials made the atmosphere in the capital even more treacherous!
There are even people in Zhejiang revolting...

Although the other party didn't even break through the county seat, they were suppressed!

But because of this incident, the world seems to be like a powder keg.
A little spark and it might explode. "

Silence is the scariest thing...

Zhang Yi nodded silently. No wonder Zhu Yuanzhang sent Jinyi guards to protect him even when he asked him to go back.

Over the years, Lao Zhu cut the sausage bit by bit and gradually gathered his power.

But at this point, it's clear that some people can't stand it anymore.

If it were a future emperor, even Zhu Biao, the throne would probably be unstable at this point.

But Zhu Yuanzhang was the founding emperor, and all of his meritorious generals are still alive.

These civil servants cannot afford to make waves.

Zhang Yi was sweating on his forehead just thinking about the current situation.

Too dangerous……

Zhang Yi understood that once the conflict between the monarch and his ministers intensified to this extent, the situation in the Ming Dynasty would be like a volcano crater.

Either the emperor suppresses the ministers, or the ministers replace the emperor.

In this current situation, there is a high probability that Lao Zhu suppressed them.

However, once the contradiction between monarch and ministers turns into a contradiction between classes, it will be easy to shake the country.

The king's will will ultimately be executed through civil servants!

Once the civil servants fail or fail to cooperate, the world's government affairs can be paralyzed.

But at least so far, it has not reached this level.

It is true that people have classes, but people are also composed of individuals.

It is impossible for everyone to have the same interests, and these contradictions will only erupt over time.

However, if another class can be cultivated, civil servants will not be irreplaceable.

The imperial court is destined to have an advantage in this battle.

Zhang Yi vaguely felt the heavy burden on him.

"It seems that I have to be more careful in my actions in the future, there are probably many people who want me dead...

Especially the gentry in Jiangnan..."

Zhang Yi already knew the situation in the DPRK and understood Zhu Yuanzhang's approach.

He nodded to show that he understood.

"Then, Master Imperial Master, I will go and get busy first!"

Zhou Zhi knew that Zhang Yi was not prepared to continue the conversation, so he left decisively.

Zhang Yi was left alone, sitting alone in the room, thoughtful.

All the way back to Beijing.

Zhang Yi passed through some county towns and state capitals, accompanied by royal guards, and he also went in and out of official inns.

But on the way, perhaps because of Zhou Tong's reminder, he did feel the hostility towards him from the officials around him.

He didn't know whether these people were hostile to him or because of this recent incident.

But Zhang Yi still paid attention to all kinds of details.

Zhu Yuanzhang was right. He could indeed suppress the dissatisfaction of those people, and the other party had nothing to do with the emperor.

But there is no guarantee that they will not anger themselves.

"The left and right are just incompetent and furious..."

As everyone hurried on, Zhang Yi and others finally returned to Yingtian Mansion.

When he came back again, he was summoned to the palace by the emperor before he even had time to settle down with his two younger brothers.

Royal study.

Zhang Yi met Zhu Yuanzhang, whom he had not seen for a long time.

After not seeing him for half a year, the emperor still looked energetic.

When he saw Zhang Yi come in, he put down his pen and asked Zhang Yi to sit aside.

"You also know the situation?"

Lao Zhu got straight to the point, and Zhang Yi nodded silently.

"These days, many officials have submitted their resignations to me...

There are many people who are passive and slack in their work!
It’s not like there are no gentry who have rebelled...

I didn't move anything, but their reaction was so big..."

When Zhu Yuanzhang said this, he sneered, and then asked Zhang Yi:
"Do you think I should compromise?"

Zhang Yi thought for a moment and shook his head:
"They are nothing!"

Along the way, he also thought about asking the emperor to compromise.

But I think of the chaos in the Ming Dynasty, and also think of the scene when the Qing Dynasty entered the country.

The background of these literati has been clearly recorded in history books.

After entering the pass, there were great scholars who interpreted the scriptures.

The Manchus never believed in the idea that the king and the scholar-bureaucrats governed the world. Under the butcher's knife of the Eight Banners, there were national heroes who could sing and cry, but more of them were people like Qian Qian and Yishui Tailiang who were just seeking fame.

The things involved in Zhu Yuanzhang's reform have indeed entered deep water areas.

But Lao Zhu also has something similar to the Eight Banners, that is, an invincible army that has experienced blood and fire.

As long as he kills hard enough, sooner or later he will be able to kill those people to death...

Zhu Yuanzhang was very pleased to see the fierceness in Zhang Yi's eyes.

He has also been under a lot of pressure recently, especially in the face of so much pressure. ,
Ever since the debate between Li Shanchang and him, the civil servants in the DPRK seemed to have changed...

Zhu Yuanzhang himself was holding back his anger, and at the same time he was also thinking, should he compromise?
“Your Majesty, literati are not one and the same.

Some people don’t do it, but there are also people who want to do something? "

With Confucianism controlling most of the elites, it would be difficult for an emperor to move forward if the entire class rejected him.

But the Manchus have already beaten him, so it can only be said that Lao Zhu's killing is not ruthless enough.

Of course, even if he didn't kill people, Zhang Yi believed that Ming Dynasty would not be isolated by all Confucian scholars.

Maybe the top group of people are like this, but others may not stand with them.

not to mention……

The calls of those great scholars are no longer what they used to be.

What is popular opinion?

In their understanding, they are the people and the common people are dogs.

In the past, they were the only ones who could herd dogs, so the emperor was afraid that they would give up the job.

But my lord, times have changed.

These people may not be irreplaceable.

"I promoted 11 people from the technocrats of your Spring and Autumn College in one go!
Those people were suddenly at peace!

Just as you said, there are also a group of Confucian scholars who will not respond to the call of the great Confucians..."

Neo-Confucianism.

In fact, many young Confucian scholars agreed with Kong Ne's call.

These people were abruptly separated from the group of Confucian scholars by Zhang Yi.

Since those people in the court can't make any noise, they are no longer irreplaceable.

They have nothing to fear!
"I'm not afraid of them, but there's no guarantee they won't be angry with you!
So, be more careful in the future! "

Zhu Yuanzhang was able to remind himself, proving that the so-called anger had actually happened long ago.

Zhang Yi nodded silently. At this point, he had already been mentally prepared.

"How's your dad's side?"

Zhu Yuanzhang changed the topic and asked about Lao Zhang's situation.

When Zhang Yi heard this, a trace of worry appeared on his face...

Seeing him like this, Lao Zhu also understood that the situation could not be optimistic.

“This is the number of days, don’t force it!

But in this case, you should get married as soon as possible. Maybe it will be a happy occasion and it will have good results...

I have already arranged for someone to arrange your wedding! "

Zhang Yi stood up and saluted the emperor solemnly.

"I have watched you grow up, this world goes by so fast!

I looked at the child who spoke freely at first, but now he wants to start a family and start a business!

I hope that after you get married, you can take on the responsibilities of a husband and father..."

When the wedding was mentioned, the emperor's eyes were filled with joy.

He had also hosted several of his sons' weddings, but he was still excited for Zhang Yi.

"Back to Your Majesty, I know!

My family will come over in a while and handle this matter personally..."

Longhu Mountain is too far away from the capital, so the wedding will most likely be held in the capital.

Zhang Yi added:

"Your Majesty, Wei Chen hopes to focus on Longhu Mountain in the past two years and spend more time with you..."

There was a trace of hesitation on Lao Zhu's face.

From the perspective of the Son of Man, he should agree with Zhang Yi's idea.

It's just that Zhang Yi has too much use value, so it would be a pity for him to waste two years in Longhu Mountain.

"The capital is not far from Longhu Mountain. In fact, you don't have to be like this..."

Lao Zhu calculated it, if Zhang Yi returned to Longhu Mountain to fulfill his filial piety, he would have been away for who knows how many years.

In addition to observing filial piety, there is a high probability that this kid will not be seen for four to five years after leaving.

Now that the reforms he was promoting were at a critical moment, he didn't want Zhang Yi to disappear for so long.

Zhang Yi smiled bitterly when he heard this.

Lao Zhu is indeed not authentic enough in this regard.

He had read Zhang Yi's original fate in history books and knew that his request for leave would most likely be rejected.

He said:

"Actually, Yao Guangxiao can help me handle everything, and even if I am in Longhu Mountain, I will not do nothing...

No, when Brother Chen comes down in a while, he may bring a generous gift to Daming! "

He downplayed it and transferred the matter of asking for leave to other places.

Lao Zhu also let nature take its course and did not mention that matter.

"What kind of gift is it?"

"A medicine! A medicine that can reduce the casualties of Ming soldiers on a large scale..."

"Oh!"

Lao Zhu became interested. The last drug Zhang Yi invented, the one who dared to say this, was allicin.

The emergence of antibiotics has indeed saved many soldiers.

However, due to the high cost, large-scale application of allicin on the battlefield is not possible for the time being.

Zhang Yi said that it can reduce the casualties of soldiers on a large scale. This must be a drug that is at least comparable to allicin.

"What is it?"

Zhang Yi did not directly answer Lao Zhu's words, but asked:

"Your Majesty, during these years when we attacked Yunnan and Guizhou and other places, when we continued to move south, did a large number of soldiers die of diseases due to acclimatization?"

Lao Zhu's face changed slightly. Speaking of this matter, it was indeed the case.

The land of Yunnan and Guizhou has many mountains and forests.

Miasma in the mountains, poisonous insects in the south.

In this era, it is a very troublesome existence.

The soldiers were not accustomed to the local environment, and even if they could capture the city, it would be difficult to establish effective rule.

However, death due to miasma cannot be counted as ordinary battle damage.
It's something that cannot be changed.

Lao Zhu never paid attention to such things that were beyond human control before, because they were things that he could not change no matter how hard he tried.

So, Zhang Yi has a solution?
Regarding Lao Zhu's questions, Zhang Yi did not give in. He told Zhu Yuanzhang about the efficacy and functions of artemisinin.

Zhu Yuanzhang was confused at first, but gradually turned into ecstasy as Zhang Yi explained.

"It turns out that the so-called miasma is also composed of many diseases...

If what you say is valid, the promotion of artemisinin may allow many immigrants to survive in the south..."

Zhu Yuanzhang was really happy.

If you want to turn a place into the territory of the Ming Dynasty, conquering it is only the first step.

How to establish effective governance is the key.

Elsewhere, according to the past practices of the Central Plains Dynasty.

Immigrating a group of people can indeed establish effective rule.

But the first prerequisite for this move is to ensure that there is farmland in the local area.

Second, we must ensure that immigrants can survive locally.

At least Zhang Yi can solve the first problem.

As for the second question...

Lao Zhu looked at Zhang Yi with interest. (End of chapter)

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