Hongwu Survival Guide

Chapter 276 It's done, it's done

When Zhu Yuan took the girls around him to try to make dust masks, the courtyard of Houhu Medical University Laboratory on the north bank of Xuanwu Lake was also busy.

Dai Sanchun not only called many students, but even Sun Shouzhen, the Shangshu lord, was here, and he was still operating it himself.

Clear target, extract solid penicillin.

However, the situation was different from what Dai Sanchun discussed with Zhu Yuan before. In the courtyard, a large table and chairs were placed.

Among them, six square tables were surrounded by eight people on each side, each with a cattail leaf fan, waving vigorously.

This was obviously not an easy job, so even though the weather was cold, beads of sweat appeared on the faces of the students fanning the wind.

On the six square tables, there is a one-foot-square glass plate, which is exactly the kind of expensive thin plate used to inlay laboratory windows.

Sun Shouzhen and the others, each holding a cup of concentrated penicillin solution refined in the laboratory, shuttled between several tables to see which glass plate the liquid tended to dry out, then dipped a brush in the solution again, and brushed a thin layer of penicillin solution on it. layer.

so repeatedly.

This is another evolution of the plan given by Zhu Yuan before noon.

Dai Sanchun was impatient, and felt that it would take too much time to wait for the Equipment Bureau under the Ministry of Medicine to make a hair dryer, so he simply used the most stupid method, calling a group of students over, and each distributed a cattail fan.

Fan it!

Dai Sanchun personally had people around him fan the wind, it was very cool and the wind was strong.

enough.

As for the hair dryer, more on that later.

After that, Sun Shouzhen, Minister of the Ministry of Medicine, and Lu Weigong, the judge of the Supreme Hospital, who heard the news, rushed over and asked about Dai Sanchun's specific situation, and they all joined in and kept busy.Not only in the courtyard, but also in the laboratory, many people are collecting penicillium in the greenhouse to make more concentrated penicillin solution for outdoor refining.

Solid penicillin.

Everyone knows Dai Sanchun's previous failed attempts, and everyone knows even more that if he can extract penicillin that can be stored for a long time without deactivation, it will be of great significance to the world.

That means that the human body, regardless of trauma or internal disease, many diseases caused by bacterial infection, will have the possibility of self-healing.

A young man Pingzhang even made an assertion that if this penicillin... or, together with many other similar antibiotics, can be widely used, coupled with the popularization of various medical and health knowledge, the average life expectancy of people in the world will be enough from the current Around 30 years old, raised to over 70 years old.

What kind of merit would it be to let everyone in the world live an extra 40 years? !
Inside the courtyard.

It has been busy for more than an hour in a blink of an eye.

With the help of other people, Dai Sanchun only focused on the last step, which was mainly a cup of penicillin concentrate for each person. When the air-dried penicillin on a square table accumulated several layers, he took it and carefully scraped it off bit by bit with a scraper.

Sun Shouzhen brushed the last bit of concentrated penicillin solution in the glass beaker onto a board, put down the beaker temporarily, and came to Dai Sanchun's residence. There was already a half-inch thick white powder inside, and I was in a daze.

Taking two steps forward, Sun Shouzhen raised his hand and put it down again. He was also excited in his heart, and asked with a trembling voice, "This...is this penicillin?"

Dai Sanchun came back to his senses, and subconsciously shook his head: "My lord, I don't know... I don't know, whether it will work or not."

After all, it has been extracted several times before, and it is also a similar white powder, but...every time, it is inactivated.

this time……

The concentrated penicillin solution was made just this morning, and based on previous experience, Dai Sanchun can guarantee that the penicillin in it is all active.

Now, without going through the previous toss about freezing and preventing, just using the most stupid method of speeding up evaporation by fanning, coupled with the cold outdoor environment, within two hours, these things were extracted... compared to before Several times, Dai Sanchun had a premonition.

This time, it works.

but……

What if not?
In the blink of an eye, Dai Sanchun was worried about gains and losses again, but he quickly put this worry aside.

If not, come again.

What are you afraid of? !
So he said to Sun Shouzhen: "My lord, I'm an official, I'm an official... use these powders to do a test."

Sun Shouzhen nodded repeatedly: "Hurry up, hurry up, there is an old man watching over here."

Not only this stupid method of extracting penicillin, Dai Sanchun also told Zhu Yuan's previous proposal.

It would be a great achievement if the solid penicillin could be extracted and kept active.

Based on this achievement, I will write a letter to His Majesty tomorrow morning, and after that, Mr. Pingzhang will help to talk about it... There is still need to talk about it. In short, the problem of the "Medical Sage Temple" will definitely be solved.

Not only that, such a great achievement... His Majesty always has to show it.

Therefore, it is conceivable that everyone will have a good life this year.

Although he had expectations, Dai Sanchun was still meticulous. In order to ensure that he would not make any mistakes, he deliberately selected a laboratory with the highest level on the west side of the main room, brought the bottle of penicillin powder extracted just now, and put on a full set of protective clothing. just entered it.

After entering the door, I first found a blank paper and wrote down the experimental records.

Dai Sanchun's apprentice Sanqi and several other doctors who accompanied him in also prepared the staphylococcus culture solution. The name of this bacteria discovered through the microscope was given by Zhu Yuan, and everyone also thought it was very vivid.

According to previous experience, it is best to take one to two days to test whether the extraction solvent is antibacterial through bacteria. However, if it is shortened, it may take six hours to produce results.

Now is the first moment of Shenshi, six hours later, tomorrow's Yinshi, just ready to set off to participate in tomorrow's morning court.

Anyway, because of this matter, everyone in the laboratory is not going to rest tonight.

Dai Sanchun wrote down the basic information of this experiment and began to operate it himself.

Take out the penicillin powder in the glass bottle just now, carefully divide it into six parts with different amounts, dissolve it with the 0.9% normal saline that the adults said, and carefully drop it on the area that has been coated with the bacteria. Six glass Petri dishes.

Six petri dishes with similar conditions are enough to test relatively accurate results.

Of course, as a comparative reference, there are also two staphylococcus petri dishes that have not been dripped with penicillin solution.

Dai Sanchun also knows that the key to this matter is whether the extracted solid penicillin can be stored for a long time at room temperature, not whether it has activity just after extraction.

Solid-state penicillin, which can be preserved for a relatively long period of time without inactivation, is a drug that really has wide application value.

However, one bite does not make a fat man.

The previous problem was that I couldn't even extract the most basic active solid penicillin. Now, what everyone is doing is to take this step.

Even if the activity of this penicillin powder can only last for a day, it is a breakthrough.

As for the subsequent things, we will talk about it in the future.

Sending the first batch of eight petri dishes into the greenhouse by himself, Dai Sanchun didn't stop, hurriedly took off his protective clothing and went outside to continue preparing for the next batch.

I really don't plan to rest tonight.

Dai Sanchun hopes to go forward tomorrow morning, and if he can see the effect, he will do another experiment to see if the penicillin powder that has been placed for six hours is still active. Therefore, the previous pre-experiment is to extract a batch of powder, Also put in the greenhouse.

The temperature of the greenhouse next to the laboratory is 36 degrees, which is equivalent to that of the human body, which is relatively high.

The previous penicillin extract, placed in such a relatively high-temperature environment, usually completely loses its activity within three hours, and no longer has a bactericidal effect.

If solid-state penicillin can last for more than six hours at the same temperature, it is enough to prove the correctness of the theory that solid-state penicillin can be preserved for a relatively long time.

At that time, the temperature will be lower, and theoretically, it will be able to be stored for a longer period of time.

In the courtyard in winter, it was so busy, it was night in a blink of an eye.

Lanterns hang.

No one left, no one complained of being tired, and even Sun Shouzhen felt that he was a little more vigorous. After eating something in a hurry, he threw himself into the continuous work again.

The night of the [-]nd day of the twelfth lunar month in the first year of Hongwu was long and short.

In the laboratory courtyard, which was brightly lit all night, it was already the beginning of Yin on the [-]rd day of the twelfth lunar month.

After all, Sun Shouzhen, who was too old and unable to stay up all night, was woken up by the court judge Lu Weigong on the reclining chair in the shabby room. Without the confusion of just waking up, he opened his eyes and asked, "But it's done?"

Lu Weigong was also excited: "My lord, it's done, it's done..."

Sun Shouzhen stretched out his hand: "Quick, quickly help the old man up."

Lu Weigong and Sun Zan, the eldest grandson who came to take care of his father because he didn't come home at night, helped Mr. Shangshu up, and stopped him to put on a fur coat first, and the three of them walked out of the room in the west wing.

Outside a row of laboratories in the north of the courtyard, under the light of lanterns, it was supposed to be the quietest time of the day, but there were a lot of people crowded in. Everyone temporarily stopped the air-drying operation on the square table in the courtyard, and attached it to a window. They were buzzing and discussing.

Seeing Sun Shouzhen approaching, everyone saluted one after another, with joy, surprise, admiration and other expressions on their expressions.

Lu Weigong led Sun Shouzhen to the lowest-level laboratory in the east where everyone gathered, but it turned out that he had already transferred here.

After entering the house, a large area of ​​candles was lit here, making it even brighter, almost daytime.

Several people in the room were surrounding Dai Sanchun who was operating the microscope. When they saw Sun Shouzhen coming in, they saluted again.

Dai Sanchun also raised his head, the joy in his expression far outweighed the tiredness, and he smiled directly at Sun Shouzhen and said, "My lord, please come write and report the good news to Your Majesty."

Sun Shouzhen knew that when it came to medicine, Dai Sanchun's personality was absolutely rigorous, so hearing him say that would be [-]% effective.

Nodding repeatedly, Sun Shouzhen still said: "Old man, take a look first, take a look first."

Dai Sanchun personally brought over the eight petri dishes that were placed on a tray at the side, put them in front of Sun Shouzhen, and introduced them one by one: "My lord, please take a look. Although the time is short, compared with these two dishes that are useless, the others In the six petri dishes, the colony growth of Staphylococcus was obviously inhibited. Take a closer look, my lord, here, here, and here are all prototypes of antibacterial rings."

Although Dai Sanchun was mainly responsible for penicillin, Sun Shouzhen paid no less attention to and understood this drug than Dai Sanchun. He could understand it at a glance, and nodded repeatedly: "Okay, okay, okay..."

Dai Sanchun also continued to smile: "My lord, hurry up and write the memorial. It's the end of the new year. I think our solid-state penicillin is no worse than that auspicious. It's a lucky start."

"Yes, yes," Sun Shouzhen nodded again, looked carefully at the petri dishes again, and said, "I'll write it now, and, who... so who, took the old man's official robe."

Sun Shouzhen's eldest son, Sun Zan, immediately agreed from the outside: "Father, you wrote, the official robe has already been brought, so I won't delay your going to court."

Sun Shouzhen agreed with a smile, and immediately sat down in front of the console beside him.

Dai Sanchun personally presented the pen and paper.

Sun Shouzhen was satisfied after writing more than a thousand words eloquently, revising it, and copying it again.

The time soon came to Yin Shizheng.

Sun Shouzhen's eldest son, Sun Zan, personally took his father to another room to change clothes and wash. Dai Sanchun, Lu Weigong and other medical officials also made preparations.

These days, everyone has suffered so much because of the matter of the 'Medical Xian Temple'. Today, because the solid-state penicillin was successfully produced, everyone understands that this is destined to be the most glorious day for the Ministry of Medicine.

Excited.

Soon, the medical department set off from Houhu Medical College.

The imperial court stipulates that officials of the sixth rank and above are not allowed to be absent from the court meeting if they have nothing to do.

So, today, even some low-level officials of the medical department who are nine ranks have followed up.

Either riding a horse, riding a car or sitting in a sedan chair, accompanied by attendants and servants with lanterns, on the small road leading to the city from the edge of Xuanwu Lake, a long string of bright people stretched out, like dazzling stars falling from the sky, shining brightly. in the world.

(End of this chapter)