bonanza

Chapter 432 The problem of not being able to get out

To be honest, Yang Dongsheng doesn't understand medicine.

But a movie he saw in his previous life let him know that developing new drugs is a long-term, costly, and very low success rate.

Engaging in new drug research and development as soon as you come up is equivalent to challenging the boxing champion just after you become a professional player, and you will almost fail [-]%.

Therefore, Yang Dongsheng temporarily gave up independent research and development of new drugs, and the current main work of the pharmaceutical branch is to produce Chinese patent medicines.

Collect prescriptions from all over the country, verify the effect, and apply for a patent if it is proved to be effective.

Yang Dongsheng didn't want to get stuck in anyone's neck for the time being. Most of these prescriptions are public, but if Yang Dongsheng doesn't apply, in a few years those fake Japanese devils named Watanabe so-and-so, or so-and-so Jingbo will bring their Japanese When the master comes to apply, it will really get stuck in our necks.

These prescriptions will also go to the United States to apply for patents, but they are not applied as medicines, but as health care products.

It is very difficult for traditional Chinese medicine to be approved by the U.S. Food and Drug Administration and enter American pharmacies. Compared with Western medicine, Chinese medicine takes a completely different route. The ingredients are complex, and many pharmacological principles cannot be explained by Western medical principles.

Moreover, American pharmaceutical companies are huge, and North America is their base. They will not allow traditional Chinese medicine to become mainstream in the United States.

In the United States, Chinese medicine practitioners cannot be doctors, but only herbal medicine consultants, and Chinese medicine does not allow intramuscular injection or intravenous drip.

In contrast, it is much simpler to apply for health care products.

In addition to the medicine Yang Dongsheng would take to treat migraines, the pharmaceutical division also produced more than a dozen Chinese patent medicines for treating tonsillitis and colds, strengthening the stomach and eliminating food, and nourishing the kidney.

Yang Dongsheng was watching, and Liang Guoqing, the manager of the Shanghai company, walked in with a group of people. Liang Guoqing saw Yang Dongsheng and nodded slightly at Yang Dongsheng.

Seeing this, Yang Dongsheng quietly followed Liang Guoqing, and those who didn't know thought he was Liang Guoqing's follower.

Liang Guoqing said as he walked, "Our traditional Chinese medicine has a history of thousands of years, and we have accumulated rich experience, but at the same time, we have also created a lot of rumors! Just like a prescription we are testing recently, it contains ginseng, ganoderma, and pearls. powder and several other precious medicinal materials. We compared the collected prescriptions and found that the dosages of other medicinals are very clear, except for the dosage and usage of ginseng, ganoderma lucidum, and pearl powder, which are different from each other. There was no pattern! Later, we simply removed those few herbs, and after the experiment, it didn’t affect the effect. It turns out that what really works for this prescription is the few cheap herbs! Ancient doctors also had to eat!”

An expert smiled when he heard the words, "It's not all for eating! I read the medical books left by a famous medical doctor in the Qing Dynasty. His early prescriptions were very simple, but later he became an imperial doctor. There will always be more ginseng, deer antler and other things for no reason! Think about it, if the prescriptions you give to princes and princesses are the same as those of common people, how can they show the difference?"

"It's good to just add something!" Another old expert sighed, "Like this artemisinin, at first we tried it repeatedly with Artemisia annua, but it didn't work. Then we almost gave up, and suddenly found that according to the medical book According to the recorded characteristics, it is not Artemisia annua at all, it should be Artemisia annua."

"Speaking of our artemisinin, I heard that the output is not stable?" Liang Guoqing remembered something, "I contacted a friend at the University of North Carolina last time, and I heard that they already have a very mature recombinant technology. Using the reproductive characteristics of Escherichia coli, many substances that used to cost a lot of money to extract are produced, and now more precise gene editing technology is being developed. I wonder how our domestic research is going?"

An expert adjusted his glasses, "We have also carried out the synthetic method of producing artemisinin, and we have achieved initial results, but the cost of the current synthetic method is still higher than that of extracting from natural substances."

Yang Dongsheng found that he had underestimated these domestic scientists before. Although they were subject to many restrictions and lagged behind the West in many aspects, they have been working hard to catch up.

"The cost of synthetic artemisinin will sooner or later be lower than the cost of extraction from natural substances, but have you figured out how to go out?" an expert who had been gloomy all of a sudden said.

Several people looked at the expert together, and the expert ignored the eyes around him and continued, "In 1987, when malaria broke out in Nigeria, Mr. Jiao and I were appointed by the institute to treat foreign aid personnel. After we got there, we also Properly treated some local malaria patients. There is an expert group of a German pharmaceutical company next to us, and they are also using their medicine to treat the local people. As a result, our artemether has excellent efficacy, tolerance and acceptability. , overall better than their chloroquine, the local people gradually came to us for treatment. But suddenly one day, the Nigerian media was full of reports about the quality of our medicines, and we were forced to return to the country. Until then Only when a German pharmaceutical company came to buy our patents did we know it was their fault."

"Business competition has always been cruel!" Liang Guoqing turned around and asked, "Have we sold to them?"

"Of course not! In the second year, we established a cooperative relationship with France's Sanofi-Sindela Fort."

"It's not just Germans, even international organizations like the World Health Organization are stuck with us. We can't enter their recommended list for the same medicine. If we replace it with Ciba-Geigy, it will immediately become a recommended medicine!"

"It's the Americans who have stuck with us!"

……

"Mr. Liang, can you tell me how you are going to pass the World Health Organization and the United States?" A person who looked like a leader asked.

"This..." Liang Guoqing was in trouble immediately, he really didn't know how to pass the World Health Organization and the United States.

At this moment, someone ran over and whispered in Liang Guoqing's ear for a while.

Liang Guoqing looked at the crowd and said, "Sorry, we have to finish our visit! We have to prepare to welcome foreign heads of state!"

(End of this chapter)